Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery
Sienski, Grzegorz, Batki, Julia, Senti, Kirsten-André, Dönertas, Derya, Tirian, Laszlo, Meixner, Katharina, Brennecke, Julius·2015·Genes & Development
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- Retrotransposons and telomeresAlla I. Kalmykova, Olesya A. Sokolova · 2023 · Biochemistry (Moscow)
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- Heritable generational epigenetic effects through small noncoding RNAJohn M. Schoelz, Nicole C. Riddle · 2019 · Elsevier eBooks
- Germline gene de-silencing by a transposon insertion is triggered by an altered landscape of local piRNA biogenesisDanny E. Miller, Kelley Van Vaerenberghe, Angela Li, Emily K. Grantham, Celeste Cummings, Marilyn Barragan, Rhonda Egidy, Allison R. Scott, Kate Hall, Anoja G. Perera et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Diptera-specific Daedalus controls Zucchini endonucleolysis in piRNA biogenesis independent of exonucleasesYuica Koga, Shigeki Hirakata, Mayu Negishi, Hiroya Yamazaki, Mikiko C. Siomi · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- RNA decay via the nuclear exosome is essential for Piwi-mediated transposon silencingChangwei Yu, Toni Manolova, László Tirián, Dominik Handler, Ulrich Hohmann, Filip Nemčko, Júlia Portell i de Montserrat, Guillaume Giraud Collet, Jakob Schnabl, Ellie Blake et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- The Piwi Pathway in Bovine Gametes and Preimplantation EmbryosStewart J. Russell · 2016 · The Atrium (University of Guelph)
- The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells by repressing expression of key spermatogenesis genesAnne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Drosophila small ovary gene ensures germline stem cell maintenance and differentiation by silencing transposons and organising heterochromatinFerenc Jankovics, Melinda Bence, Rita Sinka, Anikó Faragó, László Bodai, Aladár Pettkó‐Szandtner, Karam Ibrahim, Zsanett Takács, Alexandra Brigitta Szarka-Kovács, Miklós Erdélyi · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Understanding Nuage-mitochondrial Coupling in Drosophila piRNA BiogenesisTianfang Ge · 2018 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
- An RNA exporter that enforces a no-export policyDavid Homolka, Ramesh S. Pillai · 2019 · Nature Structural & Molecular Biology
- A SUMO-dependent regulatory switch connects the piRNA pathway to the heterochromatin machinery in DrosophilaVeselin I. Andreev, Changwei Yu, Juncheng Wang, Jakob Schnabl, László Tirián, Maja Gehre, Dominik Handler, Peter Duchek, Maria Novatchkova, Lisa Baumgartner et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- The interplay of Piwi and heterochromatin proteins in transposable element silencing in the germline of Drosophila melanogaster2018 · 11-ая Международная конференция по биоинформатике регуляции и структуры геномов и системной биологии
- The interplay of Piwi and heterochromatin proteins in transposable element silencing in the germline of Drosophila melanogaster2018
- Faculty Opinions recommendation of Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila.Mary Grace Goll · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in Caenorhabditis elegans.Alla Grishok, Ekaterina S. Gushchanskaia · 2017 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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- Non-Coding RNAs: Overview and Roles in ToxicologyGail M. Nelson, Tyler L. Bissoondial, Colette N. Miller, Brian N. Chorley · 2025 · Elsevier eBooks
- Epigenetics and Transposable ElementsClémentine Vitte, Séverine Chambeyron, Cristina P Vieira · 2025 · Wiley eBooks
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- Piwi and piRNAs repress transcription of aberrant rRNA genes containing retrotransposon fragmentsElena A. Fefelova, Aleksei S. Shatskikh, Elena A. Mikhaleva, Yuri A. Abramov, Sergey A Lavrov, Сергей Анатольевич Пирогов, Valentin A. Poltorachenko, Artem A. Ilin, Phillip D. Zamore, Mikhail S. Klenov · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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- A second genetic screen for gurken mRNA mislocalisation uncovers novel phenotypes of piRNA pathway mutants in DrosophilaSophie J. Liddell, Rahnya Taghi, Jessie-Siling Li, Sejal Sathe, Shashank Chary, Azusa Hayashi, S. Mark Wainwright, Sheena M. Pinchin, David Ish‐Horowicz, Rippei Hayashi · 2025 · Biology Open
- Transposable Elements as Drivers of Age-Related Neurodegenerative DiseaseChiara Scopa, Megan Muench, Davide Trotti · 2025 · Epigenetics and human health
- putzig safeguards genome integrity by contributing to the Piwi-mediated repression of transposon activity in the female germline of Drosophila in a two-tiered fashionLea Hüttinger, Ludmilla Kober, Mirjam Zimmermann, Sebastian Schlensog, Marc Engelhart, Anja C. Nagel · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
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- Étude de l'impact de la perte de répression des rétrovirus endogènes sur l'intégrité du génome chez la drosophile.Marianne El Barouk · 2016 · theses.fr (ABES)
- Régulations épigénétiques des éléments transposables au cours de l’ovogenèse de Drosophila melanogasterEmmanuelle Théron · 2017 · theses.fr (ABES)
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