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Cited by 679

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.

Open access
Bier, E, Vaessin, H, Shepherd, S, Lee, K, McCall, K, Barbel, S, Ackerman, L, Carretto, R, Uemura, T, Grell, E·1989·Genes & Development

Abstract

A P-element vector has been constructed and used to generate lines of flies with single autosomal P-element insertions. The lines were analyzed in two ways: (1) the identification of cis-acting patterning information within the Drosophila genome, as revealed by a lacZ reporter gene within the P element, and (2) the isolation of lethal mutations. We examined 3768 independent lines for the expression of lacZ in embryos and looked among these lines for lethal mutations affecting embryonic neurogenesis. This type of screen appears to be an effective way to find new loci that may play a role in the development of the Drosophila nervous system.

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Metadata

Authors
Bier, E., Vaessin, H., Shepherd, S., Lee, K., McCall, K., Barbel, S., Ackerman, L., Carretto, R., Uemura, T., & Grell, E.
Venue
Genes & Development
Published
1989-09
Volume
3
Issue
9
Pages
1273-1287
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2155970893
Cited by
679
References
1
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. https://app.cochat.ai/papers/10.1101/gad.3.9.1273
The paper
Bier, E., Vaessin, H., Shepherd, S., Lee, K., McCall, K., Barbel, S., Ackerman, L., Carretto, R., Uemura, T., & Grell, E. (1989). Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. Genes & Development. https://doi.org/10.1101/gad.3.9.1273

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