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Cited by 171

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A novel cell-to-cell trafficking assay indicates that the KNOX homeodomain is necessary and sufficient for intercellular protein and mRNA trafficking

Open access
Kim, Jae-Yean, Rim, Yeonggil, Wang, Jing, Jackson, David·2005·Genes & Development

Abstract

Cell-to-cell trafficking of regulatory proteins is a novel mechanism for communication during cell fate specification in plants. Although several developmental proteins traffic cell-to-cell, no signals that are both necessary and sufficient for this function in developmental proteins have been described. We developed a novel trafficking assay using trichome rescue in Arabidopsis . Fusion to KNOTTED1 (KN1) conferred gain-of-trafficking function to the cell-autonomous GLABROUS1 (GL1) protein. We show that the KNOX homeodomain (HD) is necessary and sufficient for intercellular trafficking, identifying a novel function for the HD as the minimal sequence required for trafficking of KN1 and its associated mRNA.

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Metadata

Authors
Kim, J.-Y., Rim, Y., Wang, J., & Jackson, D.
Venue
Genes & Development
Published
2005-04-01
Volume
19
Issue
7
Pages
788-793
ISSN
  • 0890-9369 (ISSN-L)
  • 1549-5477
OpenAlex
W2161166267
Cited by
171
References
1
Type
posted content
Language
en
Open access
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CoChat. (2026). Citation check: A novel cell-to-cell trafficking assay indicates that the KNOX homeodomain is necessary and sufficient for intercellular protein and mRNA trafficking. https://app.cochat.ai/papers/10.1101/gad.332805
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Kim, J.-Y., Rim, Y., Wang, J., & Jackson, D. (2005). A novel cell-to-cell trafficking assay indicates that the KNOX homeodomain is necessary and sufficient for intercellular protein and mRNA trafficking. Genes & Development. https://doi.org/10.1101/gad.332805

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