The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
Open accessAbstract
GATA-family transcription factors are critical to the development of diverse tissues. In particular, GATA-4 has been implicated in formation of the vertebrate heart. As the mouse Gata-4 knock-out is early embryonic lethal because of a defect in ventral morphogenesis, the in vivo function of this factor in heart development remains unresolved. To search for a requirement for Gata4 in heart development, we created mice harboring a single amino acid replacement in GATA-4 that impairs its physical interaction with its presumptive cardiac cofactor FOG-2. Gata4ki/ki mice die just after embryonic day (E) 12.5 exhibiting features in common with Fog2−/− embryos as well as additional semilunar cardiac valve defects and a double-outlet right ventricle. These findings establish an intrinsic requirement for GATA-4 in heart development. We also infer that GATA-4 function is dependent on interaction with FOG-2 and, very likely, an additional FOG protein for distinct aspects of heart formation.
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Cites
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.
Molkentin, J. D., Lin, Q., Duncan, S. A., & Olson, E. N. (1997) · Genes & Development · doi:10.1101/gad.11.8.1061 · Cited by 1,150
Self-citationGATA4 transcription factor is required for ventral morphogenesis and heart tube formation.
Kuo, C. T., Morrisey, E. E., Anandappa, R., Sigrist, K., Lu, M. M., Parmacek, M. S., Soudais, C., & Leiden, J. M. (1997) · Genes & Development · doi:10.1101/gad.11.8.1048 · Cited by 1,037
The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6
Molkentin, J. D. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.r000029200 · Cited by 880
Self-citationTumour predisposition in mice heterozygous for a targeted mutation in Nf1
Jacks, T., Shih, T. S., Schmitt, E. M., Bronson, R. T., Bernards, A., & Weinberg, R. A. (1994) · Nature Genetics · doi:10.1038/ng0794-353 · Cited by 778
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Self-citationArceci, R. J., King, A. A., Simon, M. C., Orkin, S. H., & Wilson, D. B. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.4.2235 · Cited by 704
Self-citationFamilial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
Nichols, K. E., Crispino, J. D., Poncz, M., White, J. G., Orkin, S. H., Maris, J. M., & Weiss, M. J. (2000) · Nature Genetics · doi:10.1038/73480 · Cited by 515
Self-citationZinc fingers are sticking together
Mackay, J. P., & Crossley, M. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(97)01168-7 · Cited by 473
The transcription factor GATA6 is essential for early extraembryonic development
Koutsourakis, M., Langeveld, A., Patient, R., Beddington, R., & Grosveld, F. (1999) · Development · doi:10.1242/dev.126.4.723 · Cited by 461
Tevosian, S. G., Deconinck, A. E., Tanaka, M., Schinke, M., Litovsky, S. H., Izumo, S., Fujiwara, Y., & Orkin, S. H. (2000) · Cell · doi:10.1016/s0092-8674(00)80885-5 · Cited by 418
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Cited by
Tevosian, S. G., Albrecht, K. H., Crispino, J. D., Fujiwara, Y., Eicher, E. M., & Orkin, S. H. (2002) · Development · doi:10.1242/dev.129.19.4627 · Cited by 369
Self-citationDevelopment of heart valves requires Gata4 expression in endothelial-derived cells
Rivera-Feliciano, J., Lee, K.-H., Kong, S. W., Rajagopal, S., Ma, Q., Springer, Z., Izumo, S., Tabin, C. J., & Pu, W. T. (2006) · Development · doi:10.1242/dev.02519 · Cited by 190
Compton, L. A., Potash, D. A., Mundell, N. A., & Barnett, J. V. (2006) · Developmental Dynamics · doi:10.1002/dvdy.20629 · Cited by 112
Qian, Y., Xiao, D., Guo, X., Chen, H., Hao, L., Ma, X., Huang, G., Ma, D., & Wang, H. (2017) · Journal of Translational Medicine · doi:10.1186/s12967-017-1173-0 · Cited by 24
Metadata
- Authors
- Crispino, J. D., Lodish, M. B., Thurberg, B. L., Litovsky, S. H., Collins, T., Molkentin, J. D., & Orkin, S. H.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2001-04-01
- Volume
- 15
- Issue
- 7
- Pages
- 839-844
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2128265565
- Cited by
- 316
- References
- 31
- Type
- posted content
- Language
- en
- Open access
- diamond
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- Crispino, J. D., Lodish, M. B., Thurberg, B. L., Litovsky, S. H., Collins, T., Molkentin, J. D., & Orkin, S. H. (2001). Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes & Development. https://doi.org/10.1101/gad.875201
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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