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Minisatellites: Mutability and Genome Architecture
Open accessAbstract
Minisatellites have been found in association with important features of human genome biology such as gene regulation, chromosomal fragile sites, and imprinting. Our knowledge of minisatellite biology has greatly increased in the past 10 years owing to the identification and careful analysis of human hypermutable minisatellites, experimental models in yeast, and recent in vitro studies of minisatellite recombination properties. In parallel, minisatellites have been put forward as potential biomarkers for the monitoring of genotoxic agents such as ionizing radiation. We summarize and discuss recent observations on minisatellites. In addition we take advantage of recent whole chromosome sequence data releases to provide a unifying view which may facilitate the annotation of tandem repeat sequences.
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Cites
Tandem repeats finder: a program to analyze DNA sequences
Benson, G. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.2.573 · Cited by 9,374
Cited by
A common sequence motif associated with recombination hot spots and genome instability in humans
Myers, S., Freeman, C., Auton, A., Donnelly, P., & McVean, G. (2008) · Nature Genetics · doi:10.1038/ng.213 · Cited by 447
Tørresen, O. K., Star, B., Mier, P., Andrade-Navarro, M. A., Bateman, A., Jarnot, P., Gruca, A., Grynberg, M., Kajava, A. V., Promponas, V. J., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz841 · Cited by 347
Bacterial strain typing in the genomic era
Li, W., Raoult, D., & Fournier, P.-E. (2009) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2009.00182.x · Cited by 340
Lindstedt, B. (2005) · ELECTROPHORESIS · doi:10.1002/elps.200500096 · Cited by 329
Le Flèche, P., Hauck, Y., Onteniente, L., Prieur, A., Denoeud, F., Ramisse, V., Sylvestre, P., Benson, G., Ramisse, F., & Vergnaud, G. (2001) · BMC Microbiology · doi:10.1186/1471-2180-1-2 · Cited by 270
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Metadata
- Authors
- Vergnaud, G., & Denoeud, F.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2000-07-01
- Volume
- 10
- Issue
- 7
- Pages
- 899-907
- ISSN
- 1088-9051 (ISSN-L)
- 1549-5469
- OpenAlex
- W2029572737
- Cited by
- 208
- References
- 1
- Type
- posted content
- Language
- en
- Open access
- bronze
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