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The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.

Bacterial strain typing in the genomic era

Open access
Li, Wenjun, Raoult, Didier, Fournier, Pierre-Edouard·2009·FEMS Microbiology Reviews

Abstract

Bacterial strain typing, or identifying bacteria at the strain level, is particularly important for diagnosis, treatment, and epidemiological surveillance of bacterial infections. This is especially the case for bacteria exhibiting high levels of antibiotic resistance or virulence, and those involved in nosocomial or pandemic infections. Strain typing also has applications in studying bacterial population dynamics. Over the last two decades, molecular methods have progressively replaced phenotypic assays to type bacterial strains. In this article, we review the current bacterial genotyping methods and classify them into three main categories: (1) DNA banding pattern-based methods, which classify bacteria according to the size of fragments generated by amplification and/or enzymatic digestion of genomic DNA, (2) DNA sequencing-based methods, which study the polymorphism of DNA sequences, and (3) DNA hybridization-based methods using nucleotidic probes. We described and compared the applications of genotyping methods to the study of bacterial strain diversity. We also discussed the selection of appropriate genotyping methods and the challenges of bacterial strain typing, described the current trends of genotyping methods, and investigated the progresses allowed by the availability of genomic sequences.

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Crossref · 10.1111/j.1574-6976.2009.00182.x

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Metadata

Authors
Li, W., Raoult, D., & Fournier, P.-E.
Venue
FEMS Microbiology Reviews
Published
2009-09
Volume
33
Issue
5
Pages
892-916
ISSN
  • 0168-6445 (ISSN-L)
  • 1574-6976
OpenAlex
W2013547178
Cited by
340
References
148
FWCI
9.45
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Bacterial strain typing in the genomic era. https://app.cochat.ai/papers/10.1111/j.1574-6976.2009.00182.x
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Li, W., Raoult, D., & Fournier, P.-E. (2009). Bacterial strain typing in the genomic era. FEMS Microbiology Reviews. https://doi.org/10.1111/j.1574-6976.2009.00182.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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