The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A First Version of the Caenorhabditis elegans Promoterome
Open accessAbstract
An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such “localizome” maps should provide information on where (in what cells or tissues) and when (at what stage of development or under what conditions) genes are expressed. They should also indicate in what cellular compartments the corresponding proteins are localized. Caenorhabditis elegans is particularly suited for the development of a localizome map since all its 959 adult somatic cells can be visualized by microscopy, and its cell lineage has been completely described. Here we address one of the challenges of C. elegans localizome mapping projects: that of obtaining a genome-wide resource of C. elegans promoters needed to generate transgenic animals expressing localization markers such as the green fluorescent protein (GFP). To ensure high flexibility for future uses, we utilized the newly developed MultiSite Gateway system. We generated and validated “version 1.1” of the Promoterome: a resource of ∼6000 C. elegans promoters. These promoters can be transferred easily into various Gateway Destination vectors to drive expression of markers such as GFP, alone (promoter::GFP constructs), or in fusion with protein-encoding open reading frames available in ORFeome resources (promoter::ORF::GFP).
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Cites
Network biology: understanding the cell's functional organization
Barabási, A.-L., & Oltvai, Z. N. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1272 · Cited by 7,903
Global analysis of protein localization in budding yeast
Huh, W.-K., Falvo, J. V., Gerke, L. C., Carroll, A. S., Howson, R. W., Weissman, J. S., & O'Shea, E. K. (2003) · Nature · doi:10.1038/nature02026 · Cited by 4,248 · cited 1×
“Such GFP-based localizome data have already proven extremely valuable in yeast (Kumar et al. 2002; Huh et al. 2003).”
BackgroundTranscriptional Regulatory Networks in Saccharomyces cerevisiae
Lee, T. I., Rinaldi, N. J., Robert, F., Odom, D. T., Bar-Joseph, Z., Gerber, G. K., Hannett, N. M., Harbison, C. T., Thompson, C. M., Simon, I., et al. (2002) · Science · doi:10.1126/science.1075090 · Cited by 2,956
A N EW A PPROACH TO D ECODING L IFE : Systems Biology
Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.2.1.343 · Cited by 1,664
Cited by
Transcriptional enhancers: from properties to genome-wide predictions
Shlyueva, D., Stampfel, G., & Stark, A. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3682 · Cited by 1,356
Single-copy insertion of transgenes in Caenorhabditis elegans
Frøkjær-Jensen, C., Wayne Davis, M., Hopkins, C. E., Newman, B. J., Thummel, J. M., Olesen, S.-P., Grunnet, M., & Jorgensen, E. M. (2008) · Nature Genetics · doi:10.1038/ng.248 · Cited by 1,163
The model organism as a system: integrating 'omics' data sets
Joyce, A. R., & Palsson, B. Ø. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1857 · Cited by 785
Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans
Dupuy, D., Bertin, N., Hidalgo, C. A., Venkatesan, K., Tu, D., Lee, D., Rosenberg, J., Svrzikapa, N., Blanc, A., Carnec, A., et al. (2007) · Nature Biotechnology · doi:10.1038/nbt1305 · Cited by 286
Self-citationAn elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans
Budovskaya, Y. V., Wu, K., Southworth, L. K., Jiang, M., Tedesco, P., Johnson, T. E., & Kim, S. K. (2008) · Cell · doi:10.1016/j.cell.2008.05.044 · Cited by 253
Metadata
- Authors
- Dupuy, D., Li, Q.-R., Deplancke, B., Boxem, M., Hao, T., Lamesch, P., Sequerra, R., Bosak, S., Doucette-Stamm, L., Hope, I. A., Hill, D. E., Walhout, A. J. M., & Vidal, M.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2004-10-15
- Volume
- 14
- Issue
- 10b
- Pages
- 2169-2175
- ISSN
- 1088-9051 (ISSN-L)
- OpenAlex
- W2104011136
- Cited by
- 176
- References
- 4
- Type
- posted content
- Language
- en
- Open access
- bronze
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- Dupuy, D., Li, Q.-R., Deplancke, B., Boxem, M., Hao, T., Lamesch, P., Sequerra, R., Bosak, S., Doucette-Stamm, L., Hope, I. A., Hill, D. E., Walhout, A. J. M., & Vidal, M. (2004). A First Version of the Caenorhabditis elegans Promoterome. Genome Research. https://doi.org/10.1101/gr.2497604
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