The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle
Open accessAbstract
To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein abundance levels for seven different stages of the parasite life cycle. A moderately high positive relationship between mRNA and protein abundance was observed for these stages; the most common discrepancy was a delay between mRNA and protein accumulation. Potentially post-transcriptionally regulated genes are identified, and families of functionally related genes were observed to share similar patterns of mRNA and protein accumulation.
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Cited by
On the Dependency of Cellular Protein Levels on mRNA Abundance
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Global signatures of protein and mRNA expression levels
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Metadata
- Authors
- Le Roch, K. G., Johnson, J. R., Florens, L., Zhou, Y., Santrosyan, A., Grainger, M., Yan, S. F., Williamson, K. C., Holder, A. A., Carucci, D. J., Yates, J. R., & Winzeler, E. A.
- Venue
- Genome Research
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2004-11
- Volume
- 14
- Issue
- 11
- Pages
- 2308-2318
- ISSN
- 1088-9051 (ISSN-L)
- OpenAlex
- W2164312318
- Cited by
- 447
- References
- 45
- Type
- posted content
- Language
- en
- Open access
- bronze
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- Le Roch, K. G., Johnson, J. R., Florens, L., Zhou, Y., Santrosyan, A., Grainger, M., Yan, S. F., Williamson, K. C., Holder, A. A., Carucci, D. J., Yates, J. R., & Winzeler, E. A. (2004). Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle. Genome Research. https://doi.org/10.1101/gr.2523904
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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