The DOI matches its Crossref record; 132 of the 132 references it cites were found in a registry or an index.
Malaria rapid diagnostic tests: challenges and prospects
Open accessAbstract
In the last decade, there has been an upsurge of interest in developing malaria rapid diagnostic test (RDT) kits for the detection of Plasmodium species. Three antigens –Plasmodiumfalciparum histidine-rich protein 2 (Pf HRP2), plasmodial aldolase and plasmodial lactate dehydrogenase (pLDH) – are currently used for RDTs. Tests targeting HRP2 contribute to more than 90 % of the malaria RDTs in current use. However, the specificities, sensitivities, numbers of false positives, numbers of false negatives and temperature tolerances of these tests vary considerably, illustrating the difficulties and challenges facing current RDTs. This paper describes recent developments in malaria RDTs, reviewing RDTs detecting Pf HRP2, pLDH and plasmodial aldolase. The difficulties associated with RDTs, such as genetic variability in the Pfhrp2 gene and the persistence of antigens in the bloodstream following the elimination of parasites, are discussed. The prospect of overcoming the problems associated with current RDTs with a new generation of alternative malaria antigen targets is also described.
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Cites
Weltgesundheitsorganisation (2005) · Cited by 3,799
The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum
Bozdech, Z., Llinás, M., Pulliam, B. L., Wong, E. D., Zhu, J., & DeRisi, J. L. (2003) · PLoS Biology · doi:10.1371/journal.pbio.0000005 · Cited by 1,728
Rapid Diagnostic Tests for Malaria Parasites
Moody, A. (2002) · Clinical Microbiology Reviews · doi:10.1128/cmr.15.1.66-78.2002 · Cited by 1,418
The Biology of heat shock proteins and molecular chaperones.
Morimoto, R. I., Tissieres, A., & Georgopoulos, C. P. (1994) · Cold Spring Harbor Laboratory eBooks · Cited by 1,243
The biology of heat shock proteins and molecular chaperones
Buchner, J. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90065-5 · Cited by 1,205
The neglected burden of Plasmodium vivax malaria
Mendis, K., Sina, B., Marchesini, P., & Carter, R. (2001) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2001.64.97 · Cited by 970
A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test (RDT)
Wongsrichanalai, C., Barcus, M. J., Muth, S., Sutamihardja, A., & Wernsdorfer, W. H. (2007) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2007.77.119 · Cited by 939
MacPherson, G. G., Warrell, M. J., White, N. J., Looareesuwan, S., & Warrell, D. A. (1985) · PubMed Central · Cited by 825
Parasite Lactate Dehydrogenase as an Assay for Plasmodium falciparum Drug Sensitivity
Makler, M. T., Ries, J. M., Williams, J. A., Bancroft, J. E., Piper, R. C., Gibbins, B. L., & Hinrichs, D. J. (1993) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1993.48.739 · Cited by 740
Biochemistry of Plasmodium (malarial parasites)
Sherman, I. W. (1979) · Microbiological Reviews · doi:10.1128/mmbr.43.4.453-495.1979 · Cited by 639
Cited by
Phillips, M. A., Burrows, J. N., Manyando, C., van Huijsduijnen, R. H., Van Voorhis, W. C., & Wells, T. N. C. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.50 · Cited by 649
Larsen, D. A., Bennett, A., Silumbe, K., Hamainza, B., Yukich, J. O., Keating, J., Littrell, M., Miller, J. M., Steketee, R. W., & Eisele, T. P. (2015) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.14-0347 · Cited by 108
Malaria diagnostic methods with the elimination goal in view
Oyegoke, O. O., Maharaj, L., Akoniyon, O. P., Kwoji, I., Roux, A. T., Adewumi, T. S., Maharaj, R., Oyebola, B. T., Adeleke, M. A., & Okpeku, M. (2022) · Parasitology Research · doi:10.1007/s00436-022-07512-9 · Cited by 82
Metadata
- Authors
- Mouatcho, J. C., & Goldring, J. P. D.
- Venue
- Journal of Medical Microbiology
- Publisher
- Microbiology Society
- Published
- 2013-10-01
- Volume
- 62
- Issue
- 10
- Pages
- 1491-1505
- ISSN
- 0022-2615 (ISSN-L)
- 1473-5644
- OpenAlex
- W1987713777
- Cited by
- 291
- References
- 132
- FWCI
- 18.59
- Type
- journal article
- Language
- en
- Open access
- hybrid
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