The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Stress modulates the use of spatial versus stimulus-response learning strategies in humans
Open accessAbstract
Animal studies provided evidence that stress modulates multiple memory systems, favoring caudate nucleus-based “habit” memory over hippocampus-based “cognitive” memory. However, effects of stress on learning strategy and memory consolidation were not differentiated. We specifically address the effects of psychosocial stress on the applied learning strategy in humans. We designed a spatial learning task that allowed differentiating spatial from stimulus-response learning strategies during acquisition. In 13 subsequent trials, participants (88 male and female students) had to locate a “win” card out of four placed at a fixed location in a 3D model of a room. Relocating one cue in the last trial allowed inferring the applied learning strategy. Half of them participated first in the “Trier Social Stress Test.” Salivary cortisol and heart rate measurements were taken. Stressed participants used a stimulus-response strategy significantly more often than controls. Subsequent verbal report revealed that spatial learners had a more complete awareness of response options than stimulus-response learners. Importantly, learning performance was not affected by stress. Taken together, stress prior to learning facilitated simple stimulus-response learning strategies in humans—at the expense of a more cognitive learning strategy. Depending on the context, we consider this as an adaptive response.
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Cited by
Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test
Allen, A. P., Kennedy, P. J., Cryan, J. F., Dinan, T. G., & Clarke, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.11.005 · Cited by 734
Stress effects on memory: An update and integration
Schwabe, L., Joëls, M., Roozendaal, B., Wolf, O. T., & Oitzl, M. S. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.07.002 · Cited by 714
Self-citationHPA axis activation by a socially evaluated cold-pressor test
Schwabe, L., Haddad, L., & Schachinger, H. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.001 · Cited by 696
Self-citationStress prompts habit behavior in humans
Schwabe, L., & Wolf, O. T. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0979-09.2009 · Cited by 606
Self-citationStress and the HPA axis: role of glucocorticoids in alcohol dependence
Stephens, M. (2012) · Alcohol Research: Current Reviews · doi:10.35946/arcr.v34.4.11 · Cited by 571
Metadata
- Authors
- Schwabe, L., Oitzl, M. S., Philippsen, C., Richter, S., Bohringer, A., Wippich, W., & Schachinger, H.
- Venue
- Learning & Memory
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2007-01
- Volume
- 14
- Issue
- 1-2
- Pages
- 109-116
- ISSN
- 1072-0502 (ISSN-L)
- 1549-5485
- OpenAlex
- W1989330193
- Cited by
- 302
- References
- 51
- Type
- posted content
- Language
- en
- Open access
- diamond
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