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The Histidine Operon

Ames, B. N., Hartman, P. E.·1963·Cold Spring Harbor Symposia on Quantitative Biology

Abstract

A series of ten enzymes in Salmonella typhimurium convert the 5-carbon chain of phosphoribosyl pyrophosphate to the 5-carbon chain of histidine (Fig. 1). The pathway of histidine biosynthesis has no branches giving rise to other essential metabolites. Most of the intermediates of the pathway have been characterized and assays for 8 of the 10 enzymes are in routine use.

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Metadata

Authors
Ames, B. N., & Hartman, P. E.
Venue
Cold Spring Harbor Symposia on Quantitative Biology
Published
1963-01-01
Volume
28
Issue
0
Pages
349-356
ISSN
  • 0091-7451 (ISSN-L)
  • 1943-4456
OpenAlex
W2030129916
Cited by
282
References
0
Type
posted content
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Histidine Operon. https://app.cochat.ai/papers/10.1101/sqb.1963.028.01.049
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Ames, B. N., & Hartman, P. E. (1963). The Histidine Operon. Cold Spring Harbor Symposia on Quantitative Biology. https://doi.org/10.1101/sqb.1963.028.01.049

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.