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Cited by 290

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Procedure for Identifying Nonsense Mutations

Open access
Berkowitz, David, Hushon, Judith M., Whitfield, Harvey J., Roth, John, Ames, Bruce N.·1968·Journal of Bacteriology

Abstract

A method has been devised for the rapid identification of nonsense mutations (UAG, UAA, UGA codons) in Salmonella . The mutations to be tested are reverted, and the revertants are replica-printed onto lactose plates spread with lawns of tester strains. These tester strains contain F′ lac episomes with nonsense mutations in the episomal Z gene. The revertants are infected with the episome from the tester strain lawn. Because S. typhimurium is unable to ferment lactose, only those revertants which have nonsense suppressors are able to grow on lactose. If colonies appear on the lactose plate, it may be concluded that the original strain carries a nonsense mutation, since nonsense suppressors suppress the mutant phenotype.

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Crossref · 10.1128/jb.96.1.215-220.1968

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Metadata

Authors
Berkowitz, D., Hushon, J. M., Whitfield, H. J., Roth, J., & Ames, B. N.
Venue
Journal of Bacteriology
Published
1968-07
Volume
96
Issue
1
Pages
215-220
ISSN
  • 0021-9193 (ISSN-L)
  • 1098-5530
OpenAlex
W1547139981
Cited by
290
References
14
FWCI
10.79
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Procedure for Identifying Nonsense Mutations. https://app.cochat.ai/papers/10.1128/jb.96.1.215-220.1968
The paper
Berkowitz, D., Hushon, J. M., Whitfield, H. J., Roth, J., & Ames, B. N. (1968). Procedure for Identifying Nonsense Mutations. Journal of Bacteriology. https://doi.org/10.1128/jb.96.1.215-220.1968

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.