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The RNA Code and Protein Synthesis
Abstract
Many properties of the RNA code which were discussed at the 1963 Cold Spring Harbor meeting were based on information obtained with randomly ordered synthetic polynucleotides. Most questions concerning the code which were raised at that time related to its fine structure, that is, the order of the bases within RNA codons. After the 1963 meetings a relatively simple means of determining nucleotide sequences of RNA codons was devised which depends upon the ability of trinucleotides of known sequence to stimulate AA-sRNA binding to ribosomes (Nirenberg and Leder, 1964). In this paper, information obtained since 1963 relating to the following topics will be discussed:
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Cited by
Chambers, I., Frampton, J., Goldfarb, P., Affara, N., McBain, W., & Harrison, P. R. (1986) · The EMBO Journal · doi:10.1002/j.1460-2075.1986.tb04350.x · Cited by 667
Efficient translation initiation dictates codon usage at gene start
Bentele, K., Saffert, P., Rauscher, R., Ignatova, Z., & Blüthgen, N. (2013) · Molecular Systems Biology · doi:10.1038/msb.2013.32 · Cited by 309
Harada, F., & Nishimura, S. (1972) · Biochemistry · doi:10.1021/bi00752a024 · Cited by 259
Dual functions of codons in the genetic code
Lobanov, A. V., Turanov, A. A., Hatfield, D. L., & Gladyshev, V. N. (2010) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409231003786094 · Cited by 64
Self-citation
Metadata
- Authors
- Nirenberg, M., Caskey, T., Marshall, R., Brimacombe, R., Kellogg, D., Doctor, B., Hatfield, D., Levin, J., Rottman, F., Pestka, S., Wilcox, M., & Anderson, F.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1966-01-01
- Volume
- 31
- Issue
- 0
- Pages
- 11-24
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W1991396713
- Cited by
- 196
- References
- 0
- Type
- posted content
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: The RNA Code and Protein Synthesis. https://app.cochat.ai/papers/10.1101/sqb.1966.031.01.008
- The paper
- Nirenberg, M., Caskey, T., Marshall, R., Brimacombe, R., Kellogg, D., Doctor, B., Hatfield, D., Levin, J., Rottman, F., Pestka, S., Wilcox, M., & Anderson, F. (1966). The RNA Code and Protein Synthesis. Cold Spring Harbor Symposia on Quantitative Biology. https://doi.org/10.1101/sqb.1966.031.01.008
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
