The DOI matches its Crossref record.
A Direct Approach to the Structure of Eukaryotic Chromosomes
Abstract
The higher orders of organization of eukaryotic genomes, both structural and with respect to specific DNA sequences, are not yet clear. One of the most intriguing problems about which little is known is the organization of chromosomes in the interphase nucleus. During interphase, replication of the DNA takes place and, in addition, specific transcription directed by developmentally controlled patterns oc-curs. It is likely that in the interphase nucleus truc-ture and function are coordinated in a carefully or-chestrated manner, and the interphase nucleus should be capable of dynamic hanges. Two extremes in model interphase systems can be considered for study. One of these is the polytene system in Dros-ophila, where early in development a group of cells
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Organization of the mitotic chromosome
Naumova, N., Imakaev, M., Fudenberg, G., Zhan, Y., Lajoie, B. R., Mirny, L. A., & Dekker, J. (2013) · Science · doi:10.1126/science.1236083 · Cited by 976
ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells
Ou, H. D., Phan, S., Deerinck, T. J., Thor, A., Ellisman, M. H., & O’Shea, C. C. (2017) · Science · doi:10.1126/science.aag0025 · Cited by 868
Kimura, K., & Hirano, T. (1997) · Cell · doi:10.1016/s0092-8674(00)80524-3 · Cited by 383
Belmont, A. S., & Bruce, K. (1994) · The Journal of cell biology · doi:10.1083/jcb.127.2.287 · Cited by 340
Lin, Y. C., Benner, C., Mansson, R., Heinz, S., Miyazaki, K., Miyazaki, M., Chandra, V., Bossen, C., Glass, C. K., & Murre, C. (2012) · Nature Immunology · doi:10.1038/ni.2432 · Cited by 281
Metadata
- Authors
- Sedat, J., & Manuelidis, L.
- Venue
- Cold Spring Harbor Symposia on Quantitative Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 1978-01-01
- Volume
- 42
- Issue
- 0
- Pages
- 331-350
- ISSN
- 0091-7451 (ISSN-L)
- 1943-4456
- OpenAlex
- W2163991860
- Cited by
- 255
- References
- 0
- Type
- posted content
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Direct Approach to the Structure of Eukaryotic Chromosomes. https://app.cochat.ai/papers/10.1101/sqb.1978.042.01.035
- The paper
- Sedat, J., & Manuelidis, L. (1978). A Direct Approach to the Structure of Eukaryotic Chromosomes. Cold Spring Harbor Symposia on Quantitative Biology. https://doi.org/10.1101/sqb.1978.042.01.035
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
