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Cited by 414

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Trapping of DNA by Thermophoretic Depletion and Convection

Braun, Dieter, Libchaber, Albert·2002·Physical Review Letters

Abstract

Thermophoresis depletes DNA from a heated spot. We quantify for the first time the thermal diffusion constant ${D}_{T}=0.4\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}8}\text{ }{\mathrm{c}\mathrm{m}}^{2}/\mathrm{s}\text{ }\mathrm{K}$ for DNA, using fluorescent dyes and laser heating. For 5 kB DNA we extrapolate a 1000-fold depletion from a temperature difference of 50 K. Surprisingly, convection generated by the same heating can turn the depletion into trapping of DNA. Trapped DNA can form point geometries $20\text{ }\ensuremath{\mu}\mathrm{m}$ in diameter with more than 1000-fold enhanced concentrations. The accumulation is driven only by temperature gradients and offers a new approach to biological microfluidics and replicating systems in prebiotic evolution.

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Metadata

Authors
Braun, D., & Libchaber, A.
Venue
Physical Review Letters
Published
2002-10-14
Volume
89
Issue
18
Pages
188103-188103
ISSN
  • 0031-9007 (ISSN-L)
  • 1079-7114
OpenAlex
W2049657380
Cited by
414
References
11
FWCI
15.31
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Trapping of DNA by Thermophoretic Depletion and Convection. https://app.cochat.ai/papers/10.1103/physrevlett.89.188103
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Braun, D., & Libchaber, A. (2002). Trapping of DNA by Thermophoretic Depletion and Convection. Physical Review Letters. https://doi.org/10.1103/physrevlett.89.188103

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