The DOI matches its Crossref record.
High-Resolution Imaging of Single Fluorescent Molecules with the Optical Near-Field of a Metal Tip
Abstract
We show that a concentration of light at a metal tip allows near-field optical imaging of single fluorescent dye molecules at very high resolution, despite strong quenching effects. Details as small as 10 nm were observed in the fluorescence patterns of single Cy-3 dyes bound to the termini of DNA. Data evaluation by model fitting determines the positions of the dyes to an accuracy even better than 1 nm and also yields their 3D orientation. The metal tip simultaneously provides high-resolution topographic imaging complementing the optical signal for a detailed surface examination.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Enhancement and Quenching of Single-Molecule Fluorescence
Anger, P., Bharadwaj, P., & Novotny, L. (2006) · Physical Review Letters · doi:10.1103/physrevlett.96.113002 · Cited by 3,158
Novotny, L., & van Hulst, N. (2011) · Nature Photonics · doi:10.1038/nphoton.2010.237 · Cited by 2,649
Effective Wavelength Scaling for Optical Antennas
Novotny, L. (2007) · Physical Review Letters · doi:10.1103/physrevlett.98.266802 · Cited by 1,121
Optical antennas direct single-molecule emission
Taminiau, T. H., Stefani, F. D., Segerink, F. B., & van Hulst, N. F. (2008) · Nature Photonics · doi:10.1038/nphoton.2008.32 · Cited by 718
Fort, E., & Grésillon, S. (2008) · Journal of Physics D: Applied Physics · doi:10.1088/0022-3727/41/1/013001 · Cited by 697
Metadata
- Authors
- Frey, H. G., Witt, S., Felderer, K., & Guckenberger, R.
- Venue
- Physical Review Letters
- Publisher
- American Physical Society (APS)
- Published
- 2004-11-10
- Volume
- 93
- Issue
- 20
- Pages
- 200801-200801
- ISSN
- 0031-9007 (ISSN-L)
- 1079-7114
- OpenAlex
- W2125236261
- Cited by
- 238
- References
- 0
- FWCI
- 12.62
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: High-Resolution Imaging of Single Fluorescent Molecules with the Optical Near-Field of a Metal Tip. https://app.cochat.ai/papers/10.1103/physrevlett.93.200801
- The paper
- Frey, H. G., Witt, S., Felderer, K., & Guckenberger, R. (2004). High-Resolution Imaging of Single Fluorescent Molecules with the Optical Near-Field of a Metal Tip. Physical Review Letters. https://doi.org/10.1103/physrevlett.93.200801
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
