The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Transcription Factor CBF4 Is a Regulator of Drought Adaptation in Arabidopsis
Open accessAbstract
In plants, low temperature and dehydration activate a set of genes containing C-repeat/dehydration-responsive elements in their promoter. It has been shown previously that the Arabidopsis CBF/DREB1 transcription activators are critical regulators of gene expression in the signal transduction of cold acclimation. Here, we report the isolation of an apparent homolog of the CBF/DREB1 proteins (CBF4) that plays the equivalent role during drought adaptation. In contrast to the three already identified CBF/DREB1 homologs, which are induced under cold stress, CBF4 gene expression is up-regulated by drought stress, but not by low temperature. Overexpression of CBF4 in transgenic Arabidopsis plants results in the activation of C-repeat/dehydration-responsive element containing downstream genes that are involved in cold acclimation and drought adaptation. As a result, the transgenic plants are more tolerant to freezing and drought stress. Because of the physiological similarity between freezing and drought stress, and the sequence and structural similarity of the CBF/DREB1 and the CBF4 proteins, we propose that the plant's response to cold and drought evolved from a common CBF-like transcription factor, first through gene duplication and then through promoter evolution.
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Cites
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Self-citationPlant cis-acting regulatory DNA elements (PLACE) database: 1999
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Self-citationArabidopsis CBF1 Overexpression Induces COR Genes and Enhances Freezing Tolerance
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Role of DREB transcription factors in abiotic and biotic stress tolerance in plants
Agarwal, P. K., Agarwal, P., Reddy, M. K., & Sopory, S. K. (2006) · Plant Cell Reports · doi:10.1007/s00299-006-0204-8 · Cited by 1,050
Physiological and molecular changes in plants grown at low temperatures
Theocharis, A., Clément, C., & Barka, E. A. (2012) · Planta · doi:10.1007/s00425-012-1641-y · Cited by 773
Dai, X., Xu, Y., Ma, Q., Xu, W., Wang, T., Xue, Y., & Chong, K. (2007) · Plant Physiology · doi:10.1104/pp.106.094532 · Cited by 594
Transcriptional regulation of drought response: a tortuous network of transcriptional factors
Singh, D., & Laxmi, A. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00895 · Cited by 462
Zhang, X., Fowler, S. G., Cheng, H., Lou, Y., Rhee, S. Y., Stockinger, E. J., & Thomashow, M. F. (2004) · The Plant Journal · doi:10.1111/j.1365-313x.2004.02176.x · Cited by 448
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Metadata
- Authors
- Haake, V., Cook, D., Riechmann, J., Pineda, O., Thomashow, M. F., & Zhang, J. Z.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-10-01
- Volume
- 130
- Issue
- 2
- Pages
- 639-648
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2143741189
- Cited by
- 760
- References
- 47
- FWCI
- 28.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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