The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Rice P1B-Type Heavy-Metal ATPase, OsHMA9, Is a Metal Efflux Protein
Open accessAbstract
P1B-type heavy-metal ATPases (HMAs) are transmembrane metal-transporting proteins that play a key role in metal homeostasis. Despite their importance, very little is known about their functions in monocot species. We report the characterization of rice (Oryza sativa) OsHMA9, a member of the P1B-type ATPase family. Semiquantitative reverse transcription-polymerase chain reaction analyses of seedlings showed that OsHMA9 expression was induced by a high concentration of copper (Cu), zinc (Zn), and cadmium. We also determined, through promoter∷β-glucuronidase analysis, that the main expression was in the vascular bundles and anthers. The OsHMA9:green fluorescence protein fusion was localized to the plasma membrane. Heterologous expression of OsHMA9 partially rescued the Cu sensitivity of the Escherichia coli copA mutant, which is defective in Cu-transporting ATPases. It did not rescue the Zn sensitivity of the zntA mutant, which is defective in Zn-transporting ATPase. To further elucidate the functional roles of OsHMA9, we isolated two independent null alleles, oshma9-1 and oshma9-2, from the T-DNA insertion population. Mutant plants exhibited the phenotype of increased sensitivity to elevated levels of Cu, Zn, and lead. These results support a role for OsHMA9 in Cu, Zn, and lead efflux from the cells. This article is the first report on the functional characterization of a P1B-type metal efflux transporter in monocots.
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“This gene helps to sequester the toxic metals, including Pb in roots, therefore detoxifying and mitigating the adverse impacts of Pb in plants (Lee et al., 2007).”
From Integrative biochar and melatonin application mitigates lead toxicity in rice by modulating antioxidant activities and iron plaque formation and downregulating the expression of metal uptake genes (2025) · cites this paper as Lee et al., 2007
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“OsHMA9, is identified as a key transporter gene involved in the uptake and bioaccumulation of Pb64.”
From Silicon and iron nanoparticles protect rice against lead (Pb) stress by improving oxidative tolerance and minimizing Pb uptake (2024) · cites this paper as [64]
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Arnon, D. I. (1949) · Plant Physiology · doi:10.1104/pp.24.1.1 · Cited by 22,451
GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants.
Jefferson, R. A., Kavanagh, T. A., & Bevan, M. W. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02730.x · Cited by 9,844
A Draft Sequence of the Rice Genome ( Oryza sativa L. ssp. indica )
Yu, J., Hu, S., Wang, J., Wong, G. K.-S., Li, S., Liu, B., Deng, Y., Dai, L., Zhou, Y., Zhang, X., et al. (2002) · Science · doi:10.1126/science.1068037 · Cited by 4,208
The map-based sequence of the rice genome
International Rice Genome Sequencing Project, & Sasaki, T. (2005) · Nature · doi:10.1038/nature03895 · Cited by 3,797
A Draft Sequence of the Rice Genome ( Oryza sativa L. ssp. japonica )
Goff, S. A., Ricke, D., Lan, T.-H., Presting, G., Wang, R., Dunn, M., Glazebrook, J., Sessions, A., Oeller, P., Varma, H., et al. (2002) · Science · doi:10.1126/science.1068275 · Cited by 2,838
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Schutzendubel, A. (2002) · Journal of Experimental Botany · doi:10.1093/jexbot/53.372.1351 · Cited by 1,990
A draft sequence of the rice genome (Oryza sativa L. ssp. indica) : The rice genome
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Molecular mechanisms of plant metal tolerance and homeostasis
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Cited by
White, P. J., & Broadley, M. R. (2009) · New Phytologist · doi:10.1111/j.1469-8137.2008.02738.x · Cited by 2,178
Copper in plants: acquisition, transport and interactions
Yruela, I. (2009) · Functional Plant Biology · doi:10.1071/fp08288 · Cited by 912
The OsHMA2 transporter is involved in root‐to‐shoot translocation of Zn and Cd in rice
TAKAHASHI, R., ISHIMARU, Y., SHIMO, H., OGO, Y., SENOURA, T., NISHIZAWA, N. K., & NAKANISHI, H. (2012) · Plant, Cell & Environment · doi:10.1111/j.1365-3040.2012.02527.x · Cited by 647
Approaches for enhanced phytoextraction of heavy metals
Bhargava, A., Carmona, F. F., Bhargava, M., & Srivastava, S. (2012) · Journal of Environmental Management · doi:10.1016/j.jenvman.2012.04.002 · Cited by 586
Implications of metal accumulation mechanisms to phytoremediation
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Metadata
- Authors
- Lee, S., Kim, Y.-Y., Lee, Y., & An, G.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-09-07
- Volume
- 145
- Issue
- 3
- Pages
- 831-842
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2083796290
- Cited by
- 289
- References
- 49
- FWCI
- 6.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Lee, S., Kim, Y.-Y., Lee, Y., & An, G. (2007). Rice P1B-Type Heavy-Metal ATPase, OsHMA9, Is a Metal Efflux Protein. Plant Physiology. https://doi.org/10.1104/pp.107.102236
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