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MYB20, MYB42, MYB43, and MYB85 Regulate Phenylalanine and Lignin Biosynthesis during Secondary Cell Wall Formation
Open accessAbstract
Lignin is a phenylpropanoid-derived polymer that functions as a major component of cell walls in plant vascular tissues. Biosynthesis of the aromatic amino acid Phe provides precursors for many secondary metabolites, including lignins and flavonoids. Here, we discovered that MYB transcription factors MYB20, MYB42, MYB43, and MYB85 are transcriptional regulators that directly activate lignin biosynthesis genes and Phe biosynthesis genes during secondary wall formation in Arabidopsis (Arabidopsis thaliana). Disruption of MYB20, MYB42, MYB43, and MYB85 resulted in growth development defects and substantial reductions in lignin biosynthesis. In addition, our data showed that these MYB proteins directly activated transcriptional repressors that specifically inhibit flavonoid biosynthesis, which competes with lignin biosynthesis for Phe precursors. Together, our results provide important insights into the molecular framework for the lignin biosynthesis pathway.
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Metadata
- Authors
- Geng, P., Zhang, S., Liu, J., Zhao, C., Wu, J., Cao, Y., Fu, C., Han, X., He, H., & Zhao, Q.
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2019-12-23
- Volume
- 182
- Issue
- 3
- Pages
- 1272-1283
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- OpenAlex
- W2997396447
- Cited by
- 325
- References
- 52
- FWCI
- 8.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: MYB20, MYB42, MYB43, and MYB85 Regulate Phenylalanine and Lignin Biosynthesis during Secondary Cell Wall Formation. https://app.cochat.ai/papers/10.1104/pp.19.01070
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- Geng, P., Zhang, S., Liu, J., Zhao, C., Wu, J., Cao, Y., Fu, C., Han, X., He, H., & Zhao, Q. (2020). MYB20, MYB42, MYB43, and MYB85 Regulate Phenylalanine and Lignin Biosynthesis during Secondary Cell Wall Formation. Plant Physiology. https://doi.org/10.1104/pp.19.01070
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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