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Molecular and Phylogenetic Analyses of the Complete MADS-Box Transcription Factor Family in Arabidopsis

Open access
Par̆enicová, Lucie, de Folter, Stefan, Kieffer, Martin, Horner, David S., Favalli, Cristina, Busscher, Jacqueline, Cook, Holly E., Ingram, Richard M., Kater, Martin M., Davies, Brendan, Angenent, Gerco C., Colombo, Lucia·2003·The Plant Cell

Abstract

MADS-box transcription factors are key regulators of several plant development processes. Analysis of the complete Arabidopsis genome sequence revealed 107 genes encoding MADS-box proteins, of which 84% are of unknown function. Here, we provide a complete overview of this family, describing the gene structure, gene expression, genome localization, protein motif organization, and phylogenetic relationship of each member. We have divided this transcription factor family into five groups (named MIKC, Mα, Mβ, Mγ, and Mδ) based on the phylogenetic relationships of the conserved MADS-box domain. This study provides a solid base for functional genomics studies into this important family of plant regulatory genes, including the poorly characterized group of M-type MADS-box proteins. MADS-box genes also constitute an excellent system with which to study the evolution of complex gene families in higher plants.

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Metadata

Authors
Par̆enicová, L., de Folter, S., Kieffer, M., Horner, D. S., Favalli, C., Busscher, J., Cook, H. E., Ingram, R. M., Kater, M. M., Davies, B., Angenent, G. C., & Colombo, L.
Venue
The Plant Cell
Published
2003-07-01
Volume
15
Issue
7
Pages
1538-1551
ISSN
  • 1040-4651 (ISSN-L)
  • 1532-298X
OpenAlex
W2136383371
Cited by
926
References
4
FWCI
42.06
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Molecular and Phylogenetic Analyses of the Complete MADS-Box Transcription Factor Family in Arabidopsis. https://app.cochat.ai/papers/10.1105/tpc.011544
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Par̆enicová, L., de Folter, S., Kieffer, M., Horner, D. S., Favalli, C., Busscher, J., Cook, H. E., Ingram, R. M., Kater, M. M., Davies, B., Angenent, G. C., & Colombo, L. (2003). Molecular and Phylogenetic Analyses of the Complete MADS-Box Transcription Factor Family in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.011544

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