The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Interactions between Plasma Membrane Aquaporins Modulate Their Water Channel Activity
Open accessAbstract
Plant plasma membrane intrinsic proteins (PIPs) cluster in two evolutionary subgroups, PIP1 and PIP2, with different aquaporin activities when expressed in Xenopus oocytes. Maize ZmPIP1;1 and ZmPIP1;2 do not increase the osmotic water permeability coefficient (Pf), whereas ZmPIP2;1, ZmPIP2;4, and ZmPIP2;5 do. Here, we show that coexpression of the nonfunctional ZmPIP1;2 and the functional ZmPIP2;1, ZmPIP2;4, or ZmPIP2;5 resulted in an increase in Pf that was dependent on the amount of injected ZmPIP1;2 complementary RNA. Confocal analysis of oocytes expressing ZmPIP1;2-green fluorescent protein (GFP) alone or ZmPIP1;2-GFP plus ZmPIP2;5 showed that the amount of ZmPIP1;2-GFP present in the plasma membrane was significantly greater in coexpressing cells. Nickel affinity chromatography purification of ZmPIP2;1 fused to a His tag coeluted with ZmPIP1;2-GFP demonstrated physical interaction and heteromerization of both isoforms. Interestingly, coexpression of ZmPIP1;1 and ZmPIP2;5 did not result in a greater increase in Pf than did the expression of ZmPIP2;5 alone, but coexpression of the ZmPIP1;1 and ZmPIP1;2 isoforms induced a Pf increase, indicating that PIP1 isoform heteromerization is required for both of them to act as functional water channels. Mutational analysis demonstrated the important role of the C-terminal part of loop E in PIP interaction and water channel activity induction. This study has revealed a new mechanism of plant aquaporin regulation that might be important in plant water relations.
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Cites
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Specific Aquaporins Facilitate the Diffusion of Hydrogen Peroxide across Membranes
Bienert, G. P., Møller, A. L. B., Kristiansen, K. A., Schulz, A., Møller, I. M., Schjoerring, J. K., & Jahn, T. P. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m603761200 · Cited by 1,306
Maurel, C., Boursiac, Y., Luu, D.-T., Santoni, V., Shahzad, Z., & Verdoucq, L. (2015) · Physiological Reviews · doi:10.1152/physrev.00008.2015 · Cited by 940
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In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning
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Zelazny, E., Borst, J. W., Muylaert, M., Batoko, H., Hemminga, M. A., & Chaumont, F. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701180104 · Cited by 323
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Metadata
- Authors
- Fetter, K., Van Wilder, V., Moshelion, M., & Chaumont, F.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-12-11
- Volume
- 16
- Issue
- 1
- Pages
- 215-228
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2050679273
- Cited by
- 451
- References
- 44
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- green
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