The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Rapid Transcriptome Changes Induced by Cytosolic Ca2+ Transients Reveal ABRE-Related Sequences as Ca2+-Responsive cis Elements in Arabidopsis
Open accessAbstract
The regulation of gene expression by cellular calcium is crucial for plant defense against biotic and abiotic stresses. However, the number of genes known to respond to specific transient calcium signals is limited, and as yet there is no definition of a calcium-responsive cis element in plants. Here, we generated specific cytosolic calcium transients in intact Arabidopsis thaliana seedlings and linked them to early transcriptome changes, followed by bioinformatic analysis of the responsive genes. A cytosolic calcium transient induced by calmodulin antagonists and blocked by lanthanides was characterized using aequorin-based luminometry and photon imaging. Analysis of transcriptome changes revealed 230 calcium-responsive genes, of which 162 were upregulated and 68 were downregulated. These include known early stress-responsive genes as well as genes of unknown function. Analysis of their upstream regions revealed, exclusively in the upregulated genes, a highly significant occurrence of a consensus sequence (P < 10−13) comprising two abscisic acid–specific cis elements: the abscisic acid–responsive element (ABRE; CACGTG[T/C/G]) and its coupling element ([C/A]ACGCG[T/C/A]). Finally, we show that a tetramer of the ABRE cis element is sufficient to confer transcriptional activation in response to cytosolic Ca2+ transients. Thus, at least for some specific Ca2+ transients and motif combinations, ABREs function as Ca2+-responsive cis elements.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures
Murashige, T., & Skoog, F. (1962) · Physiologia Plantarum · doi:10.1111/j.1399-3054.1962.tb08052.x · Cited by 67,392
Floral dip: a simplified method forAgrobacterium‐mediated transformation ofArabidopsis thaliana
Clough, S. J., & Bent, A. F. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00343.x · Cited by 21,934
Systematic determination of genetic network architecture
Tavazoie, S., Hughes, J. D., Campbell, M. J., Cho, R. J., & Church, G. M. (1999) · Nature Genetics · doi:10.1038/10343 · Cited by 2,507
Binary Agrobacterium vectors for plant transformation
Bevan, M. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.22.8711 · Cited by 2,166
Seki, M., Narusaka, M., Ishida, J., Nanjo, T., Fujita, M., Oono, Y., Kamiya, A., Nakajima, M., Enju, A., Sakurai, T., et al. (2002) · The Plant Journal · doi:10.1046/j.1365-313x.2002.01359.x · Cited by 1,924
ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis
Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.-H., Hong, X., Agarwal, M., & Zhu, J.-K. (2003) · Genes & Development · doi:10.1101/gad.1077503 · Cited by 1,673
ABFs, a Family of ABA-responsive Element Binding Factors
Choi, H.-I., Hong, J.-H., Ha, J.-O., Kang, J.-Y., & Kim, S. Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.3.1723 · Cited by 1,218
Calcium: A Central Regulator of Plant Growth and Development
Hepler, P. K. (2005) · The Plant Cell · doi:10.1105/tpc.105.032508 · Cited by 1,189
Knight, M. R., Campbell, A. K., Smith, S. M., & Trewavas, A. J. (1991) · Nature · doi:10.1038/352524a0 · Cited by 1,169
Self-citationRole of arabidopsis MYC and MYB homologs in drought- and abscisic acid-regulated gene expression.
Abe, H., Yamaguchi-Shinozaki, K., Urao, T., Iwasaki, T., Hosokawa, D., & Shinozaki, K. (1997) · The Plant Cell · doi:10.1105/tpc.9.10.1859 · Cited by 1,049
Cited by
The Language of Calcium Signaling
Dodd, A. N., Kudla, J., & Sanders, D. (2010) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-070109-104628 · Cited by 1,317
Research on plant abiotic stress responses in the post‐genome era: past, present and future
Hirayama, T., & Shinozaki, K. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04124.x · Cited by 1,215
Fujita, Y., Yoshida, T., & Yamaguchi‐Shinozaki, K. (2013) · Physiologia Plantarum · doi:10.1111/j.1399-3054.2012.01635.x · Cited by 623
Song, J., & Wang, B. (2015) · Annals of Botany · doi:10.1093/aob/mcu194 · Cited by 409
Chemical signaling under abiotic stress environment in plants
Tuteja, N., & Sopory, S. K. (2008) · Plant Signaling & Behavior · doi:10.4161/psb.3.8.6186 · Cited by 288
Metadata
- Authors
- Kaplan, B., Davydov, O., Knight, H., Galon, Y., Knight, M. R., Fluhr, R., & Fromm, H.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-09-15
- Volume
- 18
- Issue
- 10
- Pages
- 2733-2748
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2107714731
- Cited by
- 309
- References
- 53
- FWCI
- 16.65
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Rapid Transcriptome Changes Induced by Cytosolic Ca2+ Transients Reveal ABRE-Related Sequences as Ca2+-Responsive cis Elements in Arabidopsis. https://app.cochat.ai/papers/10.1105/tpc.106.042713
- The paper
- Kaplan, B., Davydov, O., Knight, H., Galon, Y., Knight, M. R., Fluhr, R., & Fromm, H. (2006). Rapid Transcriptome Changes Induced by Cytosolic Ca2+ Transients Reveal ABRE-Related Sequences as Ca2+-Responsive cis Elements in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.106.042713
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
