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A Novel Class of Gibberellin 2-Oxidases Control Semidwarfism, Tillering, and Root Development in Rice
Open accessAbstract
Gibberellin 2-oxidases (GA2oxs) regulate plant growth by inactivating endogenous bioactive gibberellins (GAs). Two classes of GA2oxs inactivate GAs through 2β-hydroxylation: a larger class of C19 GA2oxs and a smaller class of C20 GA2oxs. In this study, we show that members of the rice (Oryza sativa) GA2ox family are differentially regulated and act in concert or individually to control GA levels during flowering, tillering, and seed germination. Using mutant and transgenic analysis, C20 GA2oxs were shown to play pleiotropic roles regulating rice growth and architecture. In particular, rice overexpressing these GA2oxs exhibited early and increased tillering and adventitious root growth. GA negatively regulated expression of two transcription factors, O. sativa homeobox 1 and TEOSINTE BRANCHED1, which control meristem initiation and axillary bud outgrowth, respectively, and that in turn inhibited tillering. One of three conserved motifs unique to the C20 GA2oxs (motif III) was found to be important for activity of these GA2oxs. Moreover, C20 GA2oxs were found to cause less severe GA-defective phenotypes than C19 GA2oxs. Our studies demonstrate that improvements in plant architecture, such as semidwarfism, increased root systems and higher tiller numbers, could be induced by overexpression of wild-type or modified C20 GA2oxs.
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Cites
The neighbor-joining method: a new method for reconstructing phylogenetic trees.
(1987) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040454 · Cited by 59,715
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
Tamura, K., Dudley, J., Nei, M., & Kumar, S. (2007) · Molecular Biology and Evolution · doi:10.1093/molbev/msm092 · Cited by 28,730
Pahlich, E., & Gerlitz, C. (1980) · Phytochemistry · doi:10.1016/0031-9422(80)85004-7 · Cited by 10,599
‘Green revolution’ genes encode mutant gibberellin response modulators
Peng, J., Richards, D. E., Hartley, N. M., Murphy, G. P., Devos, K. M., Flintham, J. E., Beales, J., Fish, L. J., Worland, A. J., Pelica, F., et al. (1999) · Nature · doi:10.1038/22307 · Cited by 2,252
Gibberellin Metabolism and its Regulation
Yamaguchi, S. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092804 · Cited by 2,194
The small, versatilepPZP family ofAgrobacterium binary vectors for plant transformation
Hajdukiewicz, P., Svab, Z., & Maliga, P. (1994) · Plant Molecular Biology · doi:10.1007/bf00014672 · Cited by 1,525
Li, X., Qian, Q., Fu, Z., Wang, Y., Xiong, G., Zeng, D., Wang, X., Liu, X., Teng, S., Hiroshi, F., et al. (2003) · Nature · doi:10.1038/nature01518 · Cited by 1,235
Gibberellin metabolism: new insights revealed by the genes
Hedden, P., & Phillips, A. L. (2000) · Trends in Plant Science · doi:10.1016/s1360-1385(00)01790-8 · Cited by 1,047
Gibberellin Signaling: Biosynthesis, Catabolism, and Response Pathways
Olszewski, N., Sun, T.-P., & Gubler, F. (2002) · The Plant Cell · doi:10.1105/tpc.010476 · Cited by 1,023
Semidwarf ( sd-1 ), “green revolution” rice, contains a defective gibberellin 20-oxidase gene
Spielmeyer, W., Ellis, M. H., & Chandler, P. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.132266399 · Cited by 920
Research works printed but not linked: 17
- 1989, Proc. Natl. Acad. Sci. USA, 86, 9692, 10.1073/pnas.86.24.9692 · doi:10.1073/pnas.86.24.9692
- 1995, Biosci. Biotechnol. Biochem., 59, 285, 10.1271/bbb.59.285 · doi:10.1271/bbb.59.285
- 2007, Plant Physiol., 144, 121, 10.1104/pp.107.096586 · doi:10.1104/pp.107.096586
- 2008, Plant Cell Rep., 27, 463, 10.1007/s00299-007-0471-z · doi:10.1007/s00299-007-0471-z
- 1987, Phytochem. Bull., 19, 11
- 1995, Plant Physiol., 108, 475, 10.1104/pp.108.2.475 · doi:10.1104/pp.108.2.475
- 2007, Plant Mol. Biol., 63, 351, 10.1007/s11103-006-9093-z · doi:10.1007/s11103-006-9093-z
- 1993, FEBS Lett., 334, 365, 10.1016/0014-5793(93)80713-5 · doi:10.1016/0014-5793(93)80713-5
- 2002, Plant Physiol., 130, 2085, 10.1104/pp.008581 · doi:10.1104/pp.008581
- 2005, Plant Physiol., 138, 243, 10.1104/pp.104.056499 · doi:10.1104/pp.104.056499
- 1999, Plant Physiol., 121, 775, 10.1104/pp.121.3.775 · doi:10.1104/pp.121.3.775
- 1993, Plant Cell, 5, 1039
- 1987, Mol. Biol. Evol., 4, 406
- 2003, J. Plant Res., 116, 161, 10.1007/s10265-003-0080-z · doi:10.1007/s10265-003-0080-z
- 2002, Funct. Plant Biol., 29, 547, 10.1071/PP01205 · doi:10.1071/pp01205
- 2007, Plant Cell Physiol., 48, 555, 10.1093/pcp/pcm023 · doi:10.1093/pcp/pcm023
- 1993, Proc. Natl. Acad. Sci. USA, 90, 7401, 10.1073/pnas.90.15.7401 · doi:10.1073/pnas.90.15.7401
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Adventitious Roots and Lateral Roots: Similarities and Differences
Bellini, C., Pacurar, D. I., & Perrone, I. (2014) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050213-035645 · Cited by 624
Molecular mechanism of strigolactone perception by DWARF14
Nakamura, H., Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Fukui, K., Shi, X., Ito, E., Ito, S., Park, S.-H., et al. (2013) · Nature Communications · doi:10.1038/ncomms3613 · Cited by 378
The interaction between OsMADS57 and OsTB1 modulates rice tillering via DWARF14
Guo, S., Xu, Y., Liu, H., Mao, Z., Zhang, C., Ma, Y., Zhang, Q., Meng, Z., & Chong, K. (2013) · Nature Communications · doi:10.1038/ncomms2542 · Cited by 367
Multiple pathways regulate shoot branching
Rameau, C., Bertheloot, J., Leduc, N., Andrieu, B., Foucher, F., & Sakr, S. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2014.00741 · Cited by 357
Strigolactones stimulate internode elongation independently of gibberellins
de Saint Germain, A., Ligerot, Y., Dun, E. A., Pillot, J.-P., Ross, J. J., Beveridge, C. A., & Rameau, C. (2013) · Plant Physiology · doi:10.1104/pp.113.220541 · Cited by 166
Metadata
- Authors
- Lo, S.-F., Yang, S.-Y., Chen, K.-T., Hsing, Y.-I., Zeevaart, J. A. D., Chen, L.-J., & Yu, S.-M.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-10-01
- Volume
- 20
- Issue
- 10
- Pages
- 2603-2618
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2108918635
- Cited by
- 522
- References
- 38
- FWCI
- 10.41
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: A Novel Class of Gibberellin 2-Oxidases Control Semidwarfism, Tillering, and Root Development in Rice. https://app.cochat.ai/papers/10.1105/tpc.108.060913
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- Lo, S.-F., Yang, S.-Y., Chen, K.-T., Hsing, Y.-I., Zeevaart, J. A. D., Chen, L.-J., & Yu, S.-M. (2008). A Novel Class of Gibberellin 2-Oxidases Control Semidwarfism, Tillering, and Root Development in Rice. The Plant Cell. https://doi.org/10.1105/tpc.108.060913
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