The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Ethylene Signaling Negatively Regulates Freezing Tolerance by Repressing Expression of CBF and Type-A ARR Genes in Arabidopsis
Open accessAbstract
The phytohormone ethylene regulates multiple aspects of plant growth and development and responses to environmental stress. However, the exact role of ethylene in freezing stress remains unclear. Here, we report that ethylene negatively regulates plant responses to freezing stress in Arabidopsis thaliana. Freezing tolerance was decreased in ethylene overproducer1 and by the application of the ethylene precursor 1-aminocyclopropane-1-carboxylic acid but increased by the addition of the ethylene biosynthesis inhibitor aminoethoxyvinyl glycine or the perception antagonist Ag+. Furthermore, ethylene-insensitive mutants, including etr1-1, ein4-1, ein2-5, ein3-1, and ein3 eil1, displayed enhanced freezing tolerance. By contrast, the constitutive ethylene response mutant ctr1-1 and EIN3-overexpressing plants exhibited reduced freezing tolerance. Genetic and biochemical analyses revealed that EIN3 negatively regulates the expression of CBFs and type-A Arabidopsis response regulator5 (ARR5), ARR7, and ARR15 by binding to specific elements in their promoters. Overexpression of these ARR genes enhanced the freezing tolerance of plants. Thus, our study demonstrates that ethylene negatively regulates cold signaling at least partially through the direct transcriptional control of cold-regulated CBFs and type-A ARR genes by EIN3. Our study also provides evidence that type-A ARRs function as key nodes to integrate ethylene and cytokinin signaling in regulation of plant responses to environmental stress.
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Cites
PLANT COLD ACCLIMATION: Freezing Tolerance Genes and Regulatory Mechanisms
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Cold stress regulation of gene expression in plants
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Arabidopsis CBF1 Overexpression Induces COR Genes and Enhances Freezing Tolerance
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The role of gibberellin signalling in plant responses to abiotic stress
Colebrook, E. H., Thomas, S. G., Phillips, A. L., & Hedden, P. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.089938 · Cited by 1,082
Diverse roles of jasmonates and ethylene in abiotic stress tolerance
Kazan, K. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2015.02.001 · Cited by 854
Protein kinases in plant responses to drought, salt, and cold stress
Chen, X., Ding, Y., Yang, Y., Song, C., Wang, B., Yang, S., Guo, Y., & Gong, Z. (2021) · Journal of Integrative Plant Biology · doi:10.1111/jipb.13061 · Cited by 608
Self-citationLi, H., Ye, K., Shi, Y., Cheng, J., Zhang, X., & Yang, S. (2017) · Molecular Plant · doi:10.1016/j.molp.2017.01.004 · Cited by 426
Self-citationSong, S., Huang, H., Gao, H., Wang, J., Wu, D., Liu, X., Yang, S., Zhai, Q., Li, C., Qi, T., et al. (2014) · The Plant Cell · doi:10.1105/tpc.113.120394 · Cited by 401
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Metadata
- Authors
- Shi, Y., Tian, S., Hou, L., Huang, X., Zhang, X., Guo, H., & Yang, S.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-06
- Volume
- 24
- Issue
- 6
- Pages
- 2578-2595
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2108855886
- Cited by
- 709
- References
- 67
- FWCI
- 30.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Shi, Y., Tian, S., Hou, L., Huang, X., Zhang, X., Guo, H., & Yang, S. (2012). Ethylene Signaling Negatively Regulates Freezing Tolerance by Repressing Expression of CBF and Type-A ARR Genes in Arabidopsis. The Plant Cell. https://doi.org/10.1105/tpc.112.098640
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