The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
A Conserved Network of Transcriptional Activators and Repressors Regulates Anthocyanin Pigmentation in Eudicots
Open accessAbstract
Plants require sophisticated regulatory mechanisms to ensure the degree of anthocyanin pigmentation is appropriate to myriad developmental and environmental signals. Central to this process are the activity of MYB-bHLH-WD repeat (MBW) complexes that regulate the transcription of anthocyanin genes. In this study, the gene regulatory network that regulates anthocyanin synthesis in petunia (Petunia hybrida) has been characterized. Genetic and molecular evidence show that the R2R3-MYB, MYB27, is an anthocyanin repressor that functions as part of the MBW complex and represses transcription through its C-terminal EAR motif. MYB27 targets both the anthocyanin pathway genes and basic-helix-loop-helix (bHLH) ANTHOCYANIN1 (AN1), itself an essential component of the MBW activation complex for pigmentation. Other features of the regulatory network identified include inhibition of AN1 activity by the competitive R3-MYB repressor MYBx and the activation of AN1, MYB27, and MYBx by the MBW activation complex, providing for both reinforcement and feedback regulation. We also demonstrate the intercellular movement of the WDR protein (AN11) and R3-repressor (MYBx), which may facilitate anthocyanin pigment pattern formation. The fundamental features of this regulatory network in the Asterid model of petunia are similar to those in the Rosid model of Arabidopsis thaliana and are thus likely to be widespread in the Eudicots.
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Naing, A. H., & Kim, C. K. (2018) · Plant Molecular Biology · doi:10.1007/s11103-018-0771-4 · Cited by 322
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Metadata
- Authors
- Albert, N. W., Davies, K. M., Lewis, D. H., Zhang, H., Montefiori, M., Brendolise, C., Boase, M. R., Ngo, H., Jameson, P. E., & Schwinn, K. E.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-03
- Volume
- 26
- Issue
- 3
- Pages
- 962-980
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2096172188
- Cited by
- 800
- References
- 80
- FWCI
- 12.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Albert, N. W., Davies, K. M., Lewis, D. H., Zhang, H., Montefiori, M., Brendolise, C., Boase, M. R., Ngo, H., Jameson, P. E., & Schwinn, K. E. (2014). A Conserved Network of Transcriptional Activators and Repressors Regulates Anthocyanin Pigmentation in Eudicots. The Plant Cell. https://doi.org/10.1105/tpc.113.122069
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