Cited by 462Plant tissue culture and regenerationPlant biochemistry and biosynthesisTransgenic Plants and Applications

Plant tissue culture as a perpetual source for production of industrially important bioactive compounds

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Chandran, Hema, Meena, Mukesh, Barupal, Tansukh, Sharma, Kanika·2020·Biotechnology Reports

Abstract

Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.

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  1. [44]Gorelick J. Bernstein N. Elicitation: An underutilized tool in the development of medicinal plants as a source of therapeutic secondary metabolites Sparks D.L. Advances in Agronomy 124 2014 Elsevier Amsterdam, The Netherlands 201 230
  2. [71]Latchman D.S. Eucaryotic transcription factors 2003 Academic Press San Diego
  3. [115]Naeem M. Aftab T. Masroor K.M.A. Catharanthus Roseus. Current Research and Future Prospects 2017 Springer India 412 10.1007/978-3-319-51620-2 · DOI
  4. [138]Jordan A. Hadfield J.A. Lawrence N.J. McGown A.T. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle Med. Res Rev. 18 1998 259 296 9664292
  5. [143]Christen A.A. Bland J. Gibson G.M. Cell cultures as a means to produce taxol Proc. Amer. Assoc. Canc. Res. 30 1989 566

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Authors
Chandran, H., Meena, M., Barupal, T., & Sharma, K.
Affiliations
Mohanlal Sukhadia University (IN)
Corresponding author
Meena, Mukesh
Venue
Biotechnology Reports
Publisher
Elsevier BV
Published
2020-06
Volume
26
Pages
e00450
ISSN
2215-017X (ISSN-L)
OpenAlex
W3019219369
Cited by
462
References
147
Citations by year
2026: 44 · 2025: 78 · 2024: 92 · 2023: 102 · 2022: 83 · 2021: 52 · 2020: 11
FWCI
5.94
Type
journal article
Language
en
Open access
Locations
  • Biotechnology Reports (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
University Grants Committee
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
Keywords
plant tissue culture, secondary metabolites, bioactive compounds, bioreactors, mass production, medicinal plants, phytochemicals

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