Regulation of Protein Degradation.

Cyclin is degraded by the ubiquitin pathway

Glotzer, M., Murray, A. W., & Kirschner, M. W. (1991) · Nature · doi:10.1038/349132a0 · Cited by 2,357

Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution

Löwe, J., Stock, D., Jap, B., Zwickl, P., Baumeister, W., & Huber, R. (1995) · Science · doi:10.1126/science.7725097 · Cited by 1,525

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction.

Takeshige, K., Baba, M., Tsuboi, S., Noda, T., & Ohsumi, Y. (1992) · The Journal of cell biology · doi:10.1083/jcb.119.2.301 · Cited by 1,264

Seed storage proteins: structures and biosynthesis.

Shewry, P. R., Napier, J. A., & Tatham, A. S. (1995) · The Plant Cell · doi:10.1105/tpc.7.7.945 · Cited by 1,058

Nitrate: nutrient and signal for plant growth.

Crawford, N. M. (1995) · The Plant Cell · doi:10.1105/tpc.7.7.859 · Cited by 1,010

Maize polyubiquitin genes: structure, thermal perturbation of expression and transcript splicing, and promoter activity following transfer to protoplasts by electroporation

Christensen, A. H., Sharrock, R. A., & Quail, P. H. (1992) · Plant Molecular Biology · doi:10.1007/bf00020010 · Cited by 1,005

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

Schwob, E. (1994) · Cell · doi:10.1016/0092-8674(94)90193-7 · Cited by 890

Proteasome from Thermoplasma acidophilum : a Threonine Protease

Seemüller, E., Lupas, A., Stock, D., Löwe, J., Huber, R., & Baumeister, W. (1995) · Science · doi:10.1126/science.7725107 · Cited by 634

Molecular and Cellular Biology Associated with Endosperm Mobilization in Germinating Cereal Grains

Fincher, G. B. (1989) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.pp.40.060189.001513 · Cited by 623

Proteolysis, proteasomes and antigen presentation

Goldberg, A. L., & Rock, K. L. (1992) · Nature · doi:10.1038/357375a0 · Cited by 568

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

Holloway, S. L., Glotzer, M., King, R. W., & Murray, A. W. (1993) · Cell · doi:10.1016/0092-8674(93)90364-v · Cited by 561

Developmental and age-related processes that influence the longevity and senescence of photosynthetic tissues in arabidopsis.

Hensel, L. L., Grbić, V, Baumgarten, D. A., & Bleecker, A. B. (1993) · The Plant Cell · doi:10.1105/tpc.5.5.553 · Cited by 520

Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins.

Seufert, W., & Jentsch, S. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb08141.x · Cited by 508

Hydrolytic Enzymes in the Central Vacuole of Plant Cells

Boller, T., & Kende, H. (1979) · PLANT PHYSIOLOGY · doi:10.1104/pp.63.6.1123 · Cited by 497

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

Seufert, W., Futcher, B., & Jentsch, S. (1995) · Nature · doi:10.1038/373078a0 · Cited by 495

The multicatalytic and 26 S proteases.

Rechsteiner, M., Hoffman, L., & Dubiel, W. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)53218-x · Cited by 466

The multicatalytic proteinase complex, a major extralysosomal proteolytic system

Orlowski, M. (1990) · Biochemistry · doi:10.1021/bi00497a001 · Cited by 457

The mechanism and functions of ATP‐dependent proteases in bacterial and animal cells

GOLDBERG, A. L. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb19822.x · Cited by 450

Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival.

Heinemeyer, W., Kleinschmidt, J. A., Saidowsky, J., Escher, C., & Wolf, D. H. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07982.x · Cited by 418

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

Ghislain, M., Udvardy, A., & Mann, C. (1993) · Nature · doi:10.1038/366358a0 · Cited by 414

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor

Chen, P., Johnson, P., Sommer, T., Jentsch, S., & Hochstrasser, M. (1993) · Cell · doi:10.1016/0092-8674(93)90426-q · Cited by 394

Proteasomes: multicatalytic proteinase complexes

Rivett, A. J. (1993) · Biochemical Journal · doi:10.1042/bj2910001 · Cited by 391

Turgor-responsive gene transcription and RNA levels increase rapidly when pea shoots are wilted. Sequence and expression of three inducible genes

Guerrero, F. D., Jones, J. T., & Mullet, J. E. (1990) · Plant Molecular Biology · doi:10.1007/bf00017720 · Cited by 370

PHYTOCHROME: A Light-activated Molecular Switch that Regulates Plant Gene Expression

Quail, P. H. (1991) · Annual Review of Genetics · doi:10.1146/annurev.ge.25.120191.002133 · Cited by 338

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

Orlowski, M., Cardozo, C., & Michaud, C. (1993) · Biochemistry · doi:10.1021/bi00057a022 · Cited by 321

Structure and expression of two genes that encode distinct drought-inducible cysteine proteinases in Arabidopsis thaliana

Koizumi, M., Yamaguchi-Shinozaki, K., Tsuji, H., & Shinozaki, K. (1993) · Gene · doi:10.1016/0378-1119(93)90266-6 · Cited by 305

p34 Cdc28 -Mediated Control of Cln3 Cyclin Degradation

Yaglom, J., Linskens, M. H. K., Sadis, S., Rubin, D. M., Futcher, B., & Finley, D. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.2.731 · Cited by 291

Clp P represents a unique family of serine proteases.

Maurizi, M. R., Clark, W. P., Kim, S. H., & Gottesman, S. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38379-6 · Cited by 288

Intracellular Calcium-Dependent Proteolysis

Mellgren, R. L. (2019) · CRC Press eBooks · doi:10.1201/9781351073813 · Cited by 285

Protein Degradation in Plants

Vierstra, R. (1993) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.44.1.385 · Cited by 282

Regulated degradation of the transcription factor Gcn4.

Kornitzer, D., Raboy, B., Kulka, R. G., & Fink, G. R. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06948.x · Cited by 263

In vivo degradation of a transcriptional regulator: The yeast α2 repressor

Hochstrasser, M., & Varshavsky, A. (1990) · Cell · doi:10.1016/0092-8674(90)90481-s · Cited by 238

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit

Gordon, C., McGurk, G., Dillon, P., Rosen, C., & Hastie, N. D. (1993) · Nature · doi:10.1038/366355a0 · Cited by 236

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

Zwickl, P., Grziwa, A., Puehler, G., Dahlmann, B., Lottspeich, F., & Baumeister, W. (1992) · Biochemistry · doi:10.1021/bi00119a004 · Cited by 232

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

Hershko, A., Ganoth, D., Sudakin, V., Dahan, A., Cohen, L. H., Luca, F. C., Ruderman, J. V., & Eytan, E. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37636-6 · Cited by 229

Rapid degradation of unassembled ribulose 1,5-bisphosphate carboxylase small subunits in chloroplasts

Schmidt, G. W., & Mishkind, M. L. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.9.2632 · Cited by 227

Red light-induced formation of ubiquitin-phytochrome conjugates: Identification of possible intermediates of phytochrome degradation

Shanklin, J., Jabben, M., & Vierstra, R. D. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.2.359 · Cited by 224

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

Deshaies, R. J., Chau, V., & Kirschner, M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07004.x · Cited by 211

Molecular cloning and gibberellin-induced expression of multiple cysteine proteinases of rice seeds (oryzains).

Watanabe, H., Abe, K., Emori, Y., Hosoyama, H., & Arai, S. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55387-4 · Cited by 211

Covalent modification reactions are marking steps in protein turnover

Stadtman, E. R. (1990) · Biochemistry · doi:10.1021/bi00479a001 · Cited by 210

The ubiquitin‐mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins

Ciechanover, A., & Schwartz, A. L. (1994) · The FASEB Journal · doi:10.1096/fasebj.8.2.8119489 · Cited by 202

Posttranslational Regulation of Nitrate Reductase in Higher Plants

Kaiser, W. M., & Huber, S. C. (1994) · Plant Physiology · doi:10.1104/pp.106.3.817 · Cited by 186

Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

Wenzel, T., Eckerskorn, C., Lottspeich, F., & Baumeister, W. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00665-2 · Cited by 176

A multicomponent system that degrades proteins conjugated to ubiquitin. Resolution of factors and evidence for ATP-dependent complex formation.

Ganoth, D., Leshinsky, E., Eytan, E., & Hershko, A. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)37771-8 · Cited by 160

Degradation of Mos by the N‐terminal proline (Pro2)‐dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

Nishizawa, M., Furuno, N., Okazaki, K., Tanaka, H., Ogawa, Y., & Sagata, N. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06080.x · Cited by 128

Rapid degradation of apoplastocyanin in Cu(II)-deficient cells of Chlamydomonas reinhardtii.

Merchant, S., & Bogorad, L. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)66641-4 · Cited by 120

PRE5 and PRE6, the Last Missing Genes Encoding 20S Proteasome Subunits from Yeast? Indication for a Set of 14 Different Subunits in the Eukaryotic Proteasome Core

Heinemeyer, W., Troendle, N., Albrecht, G., & Wolf, D. H. (1994) · Biochemistry · doi:10.1021/bi00206a028 · Cited by 120

Characterization of a polyubiquitin gene from Arabidopsis thaliana

Burke, T. J., Callis, J., & Vierstra, R. D. (1988) · Molecular and General Genetics MGG · doi:10.1007/bf00339613 · Cited by 117

Characterization and sequencing of the active site of 1-aminocyclopropane-1-carboxylate synthase.

Yip, W. K., Dong, J. G., Kenny, J. W., Thompson, G. A., & Yang, S. F. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.20.7930 · Cited by 103

Characterization of a cDNA clone encoding a chloroplast-targeted Clp homologue

Moore, T., & Keegstra, K. (1993) · Plant Molecular Biology · doi:10.1007/bf00028809 · Cited by 98

Tracing intracellular proteolytic pathways. Proteolysis of fatty acid synthase and other cytoplasmic proteins in the yeast Saccharomyces cerevisiae.

Egner, R., Thumm, M., Straub, M., Simeon, A., Schüller, H., & Wolf, D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74245-8 · Cited by 83

The Ubc3 (Cdc34) Ubiquitin-Conjugating Enzyme Is Ubiquitinated and Phosphorylated In Vivo

Goebl, M. G., Goetsch, L., & Byers, B. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.5.3022 · Cited by 78

Purification and characterization of the 26 S proteasome from spinach leaves.

Fujinami, K., Tanahashi, N., Tanaka, K., Ichihara, A., Cejka, Z., Baumeister, W. P., Miyawaki, M., Sato, T., & Nakagawa, H. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47331-0 · Cited by 58

Molecular And Cellular Biology Associated With Endosperm Mobilization In Germinating Cereal Grains

Fincher, G. B. (1989) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.40.1.305 · Cited by 49

Homologs of the essential ubiquitin conjugating enzymes UBC1, 4, and 5 in yeast are encoded by a multigene family in Arabidopsis thaliana

Girod, P., Carpenter, T. B., van Nocker, S., Sullivan, M. L., & Vierstra, R. D. (1993) · The Plant Journal · doi:10.1046/j.1365-313x.1993.03040545.x · Cited by 48

Regulatory Proteins of the Proteasome

Demartino, G., & Slaughter, C. A. (2017) · Enzyme and Protein · doi:10.1159/000468689 · Cited by 46

Studies on the Yeast Proteasome Uncover Its Basic Structural Features and Multiple in vivo Functions

Hilt, W., Heinemeyer, W., & Wolf, D. H. (2017) · Enzyme and Protein · doi:10.1159/000468678 · Cited by 40

Irradiation-enhanced Phytochrome Pelletability

Quail, P. H., & Briggs, W. R. (1978) · PLANT PHYSIOLOGY · doi:10.1104/pp.62.5.773 · Cited by 38

Homologues of wheat ubiquitin-conjugating enzymes - TaUBC1 and TaUBC4 are encoded by small multigene families in Arabidopsis thaliana

Sullivan, M. L., Carpenter, T. B., & Vierstra, R. D. (1994) · Plant Molecular Biology · doi:10.1007/bf00023561 · Cited by 35

An Arabidopsis gene homologous to mammalian and insect genes encoding the largest proteasome subunit

Shirley, B. W., & Goodman, H. M. (1993) · Molecular and General Genetics MGG · doi:10.1007/bf00279901 · Cited by 25

The role of the proteasome in cellular protein degradation.

Driscoll, J. J. (1994) · PubMed · Cited by 25

[Autophagy in yeast].

Ohsumi, Y., Ohsumi, M., & Baba, M. (1993) · PubMed · Cited by 16

A cut above the rest: the regulatory function of plant proteases

Schaller, A. (2004) · Planta · doi:10.1007/s00425-004-1407-2 · Cited by 384

Cardosin A, an abundant aspartic proteinase, accumulates in protein storage vacuoles in the stigmatic papillae of Cynara cardunculus L.

Ramalho-Santos, M., Pissarra, J., Veríssimo, P., Pereira, S., Salema, R., Pires, E., & Faro, C. J. (1997) · Planta · doi:10.1007/s004250050183 · Cited by 88

Dubiumin, a chymotrypsin-like serine protease from the seeds of Solanum dubium Fresen

Mohamed Ahmed, I. A., Morishima, I., Babiker, E. E., & Mori, N. (2009) · Phytochemistry · doi:10.1016/j.phytochem.2009.01.016 · Cited by 71