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MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments
Open accessAbstract
The design and features of a beamline control software system for macromolecular crystallography (MX) experiments developed at the European Synchrotron Radiation Facility (ESRF) are described. This system, MxCuBE, allows users to easily and simply interact with beamline hardware components and provides automated routines for common tasks in the operation of a synchrotron beamline dedicated to experiments in MX. Additional functionality is provided through intuitive interfaces that enable the assessment of the diffraction characteristics of samples, experiment planning, automatic data collection and the on-line collection and analysis of X-ray emission spectra. The software can be run in a tandem client-server mode that allows for remote control and relevant experimental parameters and results are automatically logged in a relational database, ISPyB. MxCuBE is modular, flexible and extensible and is currently deployed on eight macromolecular crystallography beamlines at the ESRF. Additionally, the software is installed at MAX-lab beamline I911-3 and at BESSY beamline BL14.1.
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Cited by
Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin
Mueller, U., Darowski, N., Fuchs, M. R., Förster, R., Hellmig, M., Paithankar, K. S., Pühringer, S., Steffien, M., Zocher, G., & Weiss, M. S. (2012) · Journal of Synchrotron Radiation · doi:10.1107/s0909049512006395 · Cited by 396
Mueller, U., Förster, R., Hellmig, M., Huschmann, F. U., Kastner, A., Malecki, P., Pühringer, S., Röwer, M., Sparta, K., Steffien, M., et al. (2015) · The European Physical Journal Plus · doi:10.1140/epjp/i2015-15141-2 · Cited by 299
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling
de Araujo, M. E. G., Naschberger, A., Fürnrohr, B. G., Stasyk, T., Dunzendorfer-Matt, T., Lechner, S., Welti, S., Kremser, L., Shivalingaiah, G., Offterdinger, M., et al. (2017) · Science · doi:10.1126/science.aao1583 · Cited by 134
Degtjarik, O., Golovenko, D., Diskin-Posner, Y., Abrahmsén, L., Rozenberg, H., & Shakked, Z. (2021) · Nature Communications · doi:10.1038/s41467-021-27142-6 · Cited by 78
Hugouvieux, V., Blanc-Mathieu, R., Janeau, A., Paul, M., Lucas, J., Xu, X., Ye, H., Lai, X., Le Hir, S., Guillotin, A., et al. (2024) · The Plant Cell · doi:10.1093/plcell/koae151 · Cited by 26
Metadata
- Authors
- Gabadinho, J., Beteva, A., Guijarro, M., Rey-Bakaikoa, V., Spruce, D., Bowler, M. W., Brockhauser, S., Flot, D., Gordon, E. J., Hall, D. R., Lavault, B., McCarthy, A. A., McCarthy, J., Mitchell, E., Monaco, S., Mueller-Dieckmann, C., Nurizzo, D., Ravelli, R. B. G., Thibault, X., Walsh, M. A., Leonard, G. A., & McSweeney, S. M.
- Venue
- Journal of Synchrotron Radiation
- Published
- 2010-07-13
- Volume
- 17
- Issue
- 5
- Pages
- 700-707
- ISSN
- 0909-0495 (ISSN-L)
- OpenAlex
- W2009084519
- Cited by
- 229
- References
- 0
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Gabadinho, J., Beteva, A., Guijarro, M., Rey-Bakaikoa, V., Spruce, D., Bowler, M. W., Brockhauser, S., Flot, D., Gordon, E. J., Hall, D. R., Lavault, B., McCarthy, A. A., McCarthy, J., Mitchell, E., Monaco, S., Mueller-Dieckmann, C., Nurizzo, D., Ravelli, R. B. G., Thibault, X., . . . McSweeney, S. M. (2010). MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments. Journal of Synchrotron Radiation. https://doi.org/10.1107/s0909049510020005
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