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Monte Carlo modeling of light propagation in highly scattering tissues. II. Comparison with measurements in phantoms
Abstract
Measurements of the fluence-depth distributions and of the diffuse reflectance of 633 nm light have been made in liquid media with optical properties similar to soft tissues. The results are compared with predictions of Monte Carlo computer calculations in order to test the adequacy of Monte Carlo modeling of light transport in tissue. Except at extremely high albedo, the experimental data and the Monte Carlo results agree well for the depth dependence of the fluence as a function of incident light beam diameter and optical absorption and scattering, and for the dependence of the diffuse reflectance on the albedo. The absolute experimental values for the fluence must be renormalized by a factor which varies with the albedo in order to match the model values, and the possible sources of this discrepancy are discussed.
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Citations
Cited by
MCML—Monte Carlo modeling of light transport in multi-layered tissues
Wang, L., Jacques, S. L., & Zheng, L. (1995) · Computer Methods and Programs in Biomedicine · doi:10.1016/0169-2607(95)01640-f · Cited by 3,324
HomER: A review of time-series analysis methods for near-infrared spectroscopy of the brain
Huppert, T. J., Diamond, S. G., Franceschini, M. A., & Boas, D. A. (2009) · Applied Optics · doi:10.1364/ao.48.00d280 · Cited by 1,817
PATHOLOGIC ANALYSIS OF PHOTOTHERMAL AND PHOTOMECHANICAL EFFECTS OF LASER–TISSUE INTERACTIONS
Thomsen, S. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb09897.x · Cited by 585
Flock, S. T., Patterson, M. S., Wilson, B. C., & Wyman, D. R. (1989) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.1989.1173624 · Cited by 489
Self-citationMeglinski, I. V., & Matcher, S. J. (2002) · Physiological Measurement · doi:10.1088/0967-3334/23/4/312 · Cited by 408
Metadata
- Authors
- Flock, S. T., Wilson, B. C., & Patterson, M. S.
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 1989
- Volume
- 36
- Issue
- 12
- Pages
- 1169-1173
- ISSN
- 0018-9294 (ISSN-L)
- OpenAlex
- W2086379021
- Cited by
- 177
- References
- 0
- FWCI
- 3.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Flock, S. T., Wilson, B. C., & Patterson, M. S. (1989). Monte Carlo modeling of light propagation in highly scattering tissues. II. Comparison with measurements in phantoms. IEEE Transactions on Biomedical Engineering. https://doi.org/10.1109/10.42107
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