Extracellular Recording of Entire Neural Networks Using a Dual-Mode Microelectrode Array With 19 584 Electrodes and High SNR
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in the AP band and eight stimulation units. The capacity to simultaneously perform full-frame and high-SNR recordings endows the presented DM-MEA with great flexibility for various applications in neuroscience and pharmacology.
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Devices implemented using active structures have enabled channel counts orders of magnitude larger than passive interface structures, ranging up to tens of thousands of channels on a single probe.
“Devices implemented using active structures have enabled channel counts orders of magnitude larger than that of passive interface structures [37], ranging up to tens of thousands of channels on a single probe [38].”
From Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review (2024) · cites this paper as [38]
The Electrical Characterization section reports 19,584 active-pixel-sensor readout channels, supporting the cited claim’s count in the tens of thousands. The Measurement Setup describes a packaged microelectrode-array chip, however, not a single neural probe. The comparison with passive structures is attached to a different citation [37]. (LLM, conf=0.86)
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References 36 · Cited by 50
Research works printed but not linked: 1
- [29]Muller R Gambini S Rabaey JM A 0.013 mm25μW, DC-coupled neural signal acquisition IC with 0.5 V supply IEEE J Solid-State Circuits 2012 1 47 232 243
- Authors
- Yuan, X., Hierlemann, A., & Frey, U.
- Affiliations
- ETH Zurich (CH)
- Corresponding author
- Yuan, Xinyue
- Venue
- IEEE Journal of Solid-State Circuits
- Published
- 2021-08
- Volume
- 56
- Issue
- 8
- Pages
- 2466-2475
- ISSN
- 0018-9200 (ISSN-L)
- 1558-173X
- PMC
- PMC7611388
- OpenAlex
- W3137004510
- Cited by
- 50
- References
- 36
- Citations by year
- 2026: 7 · 2025: 11 · 2024: 10 · 2023: 8 · 2022: 9 · 2021: 5
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- IEEE Journal of Solid-State Circuits (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- European Research Council Advanced (694829 “neuroXscales”)
- Corresponding Proof-of-Concept (875609 “HD-Neu-Screen,”)
- Swiss National Science Foundation (205320_188910/1)
- European Union’s Horizon 2020 Research and Innovation Programme (863245 (NEUREKA))
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced MEMS and NEMS Technologies
- Keywords
- extracellular recording, artificial neural networks, stimulation, high signal-to-noise ratio
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