The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cucurbiturils: Molecular Nanocapsules for Time-Resolved Fluorescence-Based Assays
Abstract
A new fluorescent host-guest system based on the inclusion of the fluorophore 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) into the cavity of the molecular container compound cucurbit[7]uril (CB7) has been designed which possesses an exceedingly long-lived emission (690 ns in aerated water). The large binding constant of (4 +/- 1) x 10(5) M(-1) along with the resistance of the CB7.DBO complex toward external fluorescence quenchers allow the use of CB7 as an enhancer in time-resolved fluorescence-based assays, e.g., to screen enzyme activity or inhibition by using DBO-labeled peptides as substrates. The response of CB7.DBO to different environmental conditions and possible quenchers are described.
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Cites
Introduction and General Overview of Cyclodextrin Chemistry
Szejtli, J. (1998) · Chemical Reviews · doi:10.1021/cr970022c · Cited by 5,016
Cited by
Taylor, R. W., Lee, T.-C., Scherman, O. A., Esteban, R., Aizpurua, J., Huang, F. M., Baumberg, J. J., & Mahajan, S. (2011) · ACS Nano · doi:10.1021/nn200250v · Cited by 355
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Metadata
- Authors
- Marquez, C., Huang, F., & Nau, W. M.
- Venue
- IEEE Transactions on Nanobioscience
- Published
- 2004-03
- Volume
- 3
- Issue
- 1
- Pages
- 39-45
- ISSN
- 1536-1241 (ISSN-L)
- OpenAlex
- W2101184693
- Cited by
- 162
- References
- 1
- FWCI
- 4.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Marquez, C., Huang, F., & Nau, W. M. (2004). Cucurbiturils: Molecular Nanocapsules for Time-Resolved Fluorescence-Based Assays. IEEE Transactions on Nanobioscience. https://doi.org/10.1109/tnb.2004.824269
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