The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
The prevention and treatment of postpartum haemorrhage: what do we know, and where do we go to next?
Abstract
Postpartum haemorrhage (PPH) remains a major cause of maternal deaths worldwide, and is estimated to cause the death of a woman every 10 minutes. This review presents the latest clinical advice, including new evidence on controlled cord traction, misoprostol, and oxytocin. The controversy around the diagnosis of PPH, the limitations of universal prophylaxis, and novel ways to provide obstetric first aid are also presented. It ends with a call to develop high‐quality front‐line obstetric services that can deal rapidly with unexpected haemorrhages as well as minimising blood loss at critical times: major abruption, placenta praevia, and caesarean for prolonged labour.
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“Oxytocin is given at much higher doses to prevent post‐partum haemorrhage 59, but this action appears to be mediated not by oxytocin receptors but by V1a receptors on the uterine artery 60.”
From Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers (2016) · cites this paper as [59]
Citations
Cites
Global causes of maternal death: a WHO systematic analysis
Say, L., Chou, D., Gemmill, A., Tunçalp, Ö., Moller, A.-B., Daniels, J., Gülmezoglu, A. M., Temmerman, M., & Alkema, L. (2014) · The Lancet Global Health · doi:10.1016/s2214-109x(14)70227-x · Cited by 6,582
Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes
McDonald, S. J., Middleton, P., Dowswell, T., & Morris, P. S. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004074.pub3 · Cited by 890
Carroli, G., & Mignini, L. E. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000081.pub2 · Cited by 788
Prevention and Management of Postpartum Haemorrhage
(2016) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14178 · Cited by 785
Knight, M., Callaghan, W. M., Berg, C. J., Alexander, S., Bouvier‐Colle, M., Ford, J. B., Joseph, K. S., Lewis, G., Liston, R. M., Roberts, C. L., et al. (2009) · BMC Pregnancy and Childbirth · doi:10.1186/1471-2393-9-55 · Cited by 701
St Anthony's fire and living ligatures: a short history of ergometrine
Costa, C. M. D. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08658-0 · Cited by 459
Active versus expectant management for women in the third stage of labour
Begley, C., Gyte, G. M., Devane, D., McGuire, W. L., & Weeks, A. D. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007412.pub4 · Cited by 448
Self-citationSheldon, W. R., Blum, J., Vogel, J. P., Souza, J. P., Gülmezoglu, A. M., & Winikoff, B. (2014) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.12636 · Cited by 378
Active Management of the Third Stage of Labour: Prevention and Treatment of Postpartum Hemorrhage
Leduc, D. C., Senikas, V., Lalonde, A. B., Leduc, D. C., Ballerman, C., Biringer, A. B., Delaney, M., Duperron, L., Girard, I., Jones, D., et al. (2009) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)34329-8 · Cited by 369
Uterine compression sutures: surgical management of postpartum hemorrhage
Hayman, R. G. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(01)01643-x · Cited by 357
Research works printed but not linked: 3
- Confidential Enquiry into Maternal and Child Health (CEMACH), 2006, Saving Mothers' Lives 2003‐2005
- World Health Organization, 2012, WHO Recommendations for the Prevention and Treatment of Postpartum Haemorrhage
- National Collaborating Centre for Women's and Children's Health (NCCWCH), 2007, Intrapartum Care
Cited by
Sorted by citations
FIGO recommendations on the management of postpartum hemorrhage 2022
Escobar, M. F., Nassar, A. H., Theron, G. B., Barnea, E. R., Nicholson, W. K., Ramašauskaitė, D., Lloyd, I., Chandraharan, E., Miller, S., Burke, T. F., et al. (2022) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.14116 · Cited by 413
Cai, J., Ribkoff, J., Olson, S. R., Raghunathan, V. M., Al-Samkari, H. T., DeLoughery, T. G., & Shatzel, J. J. (2019) · European Journal Of Haematology · doi:10.1111/ejh.13348 · Cited by 258
Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers
Leng, G., & Sabatier, N. (2016) · Journal of Neuroendocrinology · doi:10.1111/jne.12413 · Cited by 237
“Oxytocin is given at much higher doses to prevent post-partum haemorrhage (59), but this action appears to be mediated not by oxytocin receptors but by V1a receptors on the uterine artery (60).”
BackgroundKaraca, Z., Laway, B. A., Dökmetaş, H. S., Atmaca, H., & Keleştimur, F. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.92 · Cited by 117
Progress in understanding electro-mechanical signalling in the myometrium
Wray, S., Burdyga, T. V., Noble, D., Noble, K., Borysova, L., & Arrowsmith, S. (2014) · Acta Physiologica · doi:10.1111/apha.12431 · Cited by 69
“…be described as a perturbation in the normal progression of labour due to inefficient uterine action (Wray 2007) Likely, mechanisms involve an increase in lactate, a decrease in pH and reduced Ca entry into the myometrial cells (Crichton et al. 1993, Quenby et al. 2004, Wiberg-Itzel et al. 2008).”
Background
Metadata
- Authors
- Weeks, A.
- Affiliations
- University of Liverpool (GB)
- Corresponding author
- Weeks, A
- ORCID
- Weeks, A
- Venue
- BJOG: An International Journal of Obstetrics & Gynaecology
- Publisher
- Wiley
- Published
- 2014-10-07
- Volume
- 122
- Issue
- 2
- Pages
- 202-210
- ISSN
- 0306-5456 (ISSN-L)
- 1470-0328
- 1471-0528
- OpenAlex
- W1984295142
- Cited by
- 192
- References
- 63
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 11 · 2023: 17 · 2022: 27 · 2021: 21 · 2020: 24 · 2019: 21 · 2018: 12 · 2017: 12 · 2016: 16 · 2015: 7 · 2014: 1
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Gynuity Health Projects (MamaMiso)
- NIHR (II-LA-0712-20007)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Health Sciences › Medicine › Hematology › Blood transfusion and management
- Keywords
- postpartum hemorrhage, maternal mortality, controlled cord traction, misoprostol, oxytocin, placental abruption, placenta previa, bleeding prevention
- MeSH terms
- Blood Transfusion, Delivery of Health Care, Female, Postpartum Hemorrhage, Home Childbirth, Humans, Labor Stage, Third, Oxytocics, Pregnancy, Compression Bandages
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