The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Bioavailability and bioaccessibility of food bioactive compounds; overview and assessment by in vitro methods
Abstract
Oral bioavailability is the key to the bioefficiency of food bioactive ingredients; it evaluates the relationship between foods and their health benefits. The analysis of the main factors limiting the oral bioavailability (bioaccessibility, absorption, and transformation) has led to the proposal of classification systems for pharmaceuticals and nutraceuticals (Biopharmaceuticals Classification System and Nutraceutical Bioavailability Classification Scheme). Based on the relevant studies published in the last decade, this review presents the essential aspects regarding the factors limiting the oral bioavailability of the biocomponents and different in vitro methods used to investigate the mechanisms involved in the digestion, absorption, and metabolism of biocomponents, particularly encapsulated bioactive compounds. Oral bioavailability investigated by in vitro studies provides the food and drug manufacturers with information to formulate delivery systems more efficiently and to determine the dosage of biocomponents for increase the health benefits and avoid or reduce the risk of toxicity.
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Cites
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Simulated Biological Fluids with Possible Application in Dissolution Testing
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Cited by
Sorasitthiyanukarn, F. N., Muangnoi, C., Rojsitthisak, P., & Rojsitthisak, P. (2022) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2021.107246 · Cited by 115
Metadata
- Authors
- Dima, C., Assadpour, E., Dima, S., & Jafari, S. M.
- Venue
- Comprehensive Reviews in Food Science and Food Safety
- Publisher
- Wiley
- Published
- 2020-08-31
- Volume
- 19
- Issue
- 6
- Pages
- 2862-2884
- ISSN
- 1541-4337 (ISSN-L)
- OpenAlex
- W3082962150
- Cited by
- 304
- References
- 82
- FWCI
- 9.85
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
