The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Corticosteroid therapy in drug‐induced liver injury: Pros and cons
Abstract
Drug‐induced liver injury (DILI) is a liver toxicity induced by a drug or its metabolite. The incidence of DILI continues to increase and it has been an enormous challenge worldwide, while the prognosis is not optimistic. Currently, the most effective treatment for DILI is to suspend the offending drug(s) and to avoid re‐exposure, with no definitive therapy available for idiosyncratic DILI with or without acute liver failure. Given the anti‐inflammatory effects of corticosteroids, they have been widely used in DILI in clinical practice, although their efficacy remains controversial. Several studies have shown their beneficial effects but a few reports have refuted the efficacy of corticosteroids in treating patients with DILI. In this review, we summarized the history and current status of corticosteroid use in liver diseases and the pros and cons of corticosteroid treatment in DILI, and we explored the DILI candidates who may benefit from corticosteroid therapy, the administration route and dosage, and the adverse effects related to corticosteroid use.
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In the case of DI-ALH, steroid dosage is usually determined based on the principal investigator's personal experience.
“In the case of DI-ALH, steroid dosage is usually determined based on the principal investigator’s personal experience.”
From Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report (2023) · cites this paper as [74]
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Andrade, R. J., Aithal, G. P., de Boer, Y. S., Liberal, R., Gerbes, A., Regev, A., Terziroli Beretta-Piccoli, B., Schramm, C., Kleiner, D. E., De Martin, E., et al. (2023) · Journal of Hepatology · doi:10.1016/j.jhep.2023.04.033 · Cited by 166
Biologic and checkpoint inhibitor‐induced liver injury: a systematic literature review
Shah, P., Sundaram, V., & Björnsson, E. (2020) · Hepatology Communications · doi:10.1002/hep4.1465 · Cited by 64
Metadata
- Authors
- Hu, P. F., & Xie, W. F.
- Affiliations
- Department of Gastroenterology Changzheng Hospital, Second Military Medical University Shanghai China
- ORCID
- Xie, Wei Fen
- Venue
- Journal of Digestive Diseases
- Publisher
- Wiley
- Published
- 2019-01-24
- Volume
- 20
- Issue
- 3
- Pages
- 122-126
- ISSN
- 1751-2972
- 1751-2980
- Cited by
- 56
- References
- 3
- Language
- en
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