Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence: Ibudilast and alcohol

Bell, Richard L., Lopez, Marcelo F., Cui, Changhai, Egli, Mark, Johnson, Kirk W., Franklin, Kelle M., Becker, Howard C.·2015·Addiction Biology
DOI 10.1111/adb.12106

Cited by (138)

Items 101–138 of 138

  1. Transcriptional Regulators as Targets for Alcohol Pharmacotherapies
    Antonia M. Savarese, Amy W. Lasek · 2018 · Handbook of experimental pharmacology
  2. Transcriptomic analysis reveals moderate modulation of macrophage migration inhibitory factor superfamily genes in alcohol use disorders
    Maria Cristina Petralia, Emanuela Mazzon, Katia Mangano, Paolo Fagone, Roberto Di Marco, Luca Falzone, Maria Sofia Basile, Ferdinando Nicoletti, Eugenio Cavalli · 2020 · Experimental and Therapeutic Medicine
  3. Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking
    Kyle T. Brown, Sophia C. Levis, Casey E. O’Neill, Catherine L. Levy, Kenner C. Rice, Linda R. Watkins, Ryan K. Bachtell · 2023 · Psychopharmacology
  4. Approved, Promising, and Experimental Medications for Treatment of Alcohol Use Disorder
    András H. Lékó, Mehdi Farokhnia, Lorenzo Leggio · 2023 · Springer eBooks
  5. Therapeutic perspectives on PDE4B inhibition in adipose tissue dysfunction and chronic liver injury
    Dalton W. Staller, Robert G. Bennett, Ram I. Mahato · 2024 · Expert Opinion on Therapeutic Targets
  6. Repurposing Tigecycline for the Treatment of Alcohol Use Disorder
    Alfredo Oliveros, Doo‐Sup Choi · 2017 · Alcoholism Clinical and Experimental Research
  7. Contribution of Visceral Systems to the Development of Substance Use Disorders: Translational Aspects of Interaction between Central and Peripheral Mechanisms
    Danil Peregud, Natalia V. Gulyaeva · 2024 · Biochemistry (Moscow)
  8. Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice
    Jing Shi, Huaxia Liu, Jianchun Pan, Jie Chen, Nianping Zhang, Kaiping Liu, Ning Fei, James M. O’Donnell, Han‐Ting Zhang, Ying Xu · 2018 · Psychopharmacology
  9. The FDA-approved drug apremilast suppresses alcohol intake: clinical and pre-clinical validation
    Kolter B. Grigsby, Regina A. Mangieri, Amanda J. Roberts, Marcelo J Lopez, Alexander Tran, Evan J. Firsick, Kayla G. Townsley, Alan Beneze, Jessica Bess, Toby K. Eisenstein et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Morphine self-administration is inhibited by the antioxidant N‐acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration
    Marı́a Elena Quintanilla, Paola Morales, Daniela Santapau, Javiera Gallardo, Rocío Rebolledo, Gabriel Riveras, Tirso Acuña, Mario Herrera‐Marschitz, Yedy Israel, Fernando E. Ezquer · 2024 · PLoS ONE
  11. An assessment of the utilization of the preclinical rodent model literature in clinical trials of putative therapeutics for the treatment of alcohol use disorders
    Ashley M. Barajaz, Christopher L. Kliethermes · 2017 · Drug and Alcohol Dependence
  12. Clinical Treatment of Addictive Disorders with N-Acetylcysteine
    Gregory L. Powell, Erin A. McClure, Michael Foster Olive, Cassandra D. Gipson · 2018 · Springer eBooks
  13. Identifying drug targets for schizophrenia through gene prioritization
    Julia Kraft, Alice Braun, Swapnil Awasthi, Georgia Panagiotaropoulou, Marijn Schipper, Nathaniel Y. Bell, Daniëlle Posthuma, Antonio F. Pardiñas, Stephan Ripke, Karl Heilbron · 2024 · medRxiv
  14. Neuroimmune modulators as novel pharmacotherapies for substance use disorders
    Erica N. Grodin · 2024 · Brain Behavior & Immunity - Health
  15. Targeting Phosphodiesterases in Pharmacotherapy for Substance Dependence
    Rui-Ting Wen, Jian‐Hui Liang, Han‐Ting Zhang · 2017 · Advances in neurobiology
  16. Cannabidiol dose dependently reduces alcohol intake in mice via a non‐5‐HT1A receptor mechanism: Exploration of other potential receptor targets
    Connie J. Badolato, Erin A. Lynch, Jonathon Carl Arnold, Iain S. McGregor, Michael T. Bowen · 2025 · British Journal of Pharmacology
  17. Effects of the Phosphodiesterase 10A Inhibitor MR1916 on Alcohol Self-Administration and Striatal Gene Expression in Post-Chronic Intermittent Ethanol-Exposed Rats
    Luísa Becker Bertotto, Dolly Lampson-Stixrud, Anushka Sinha, Nicki K. Rohani, Isabella Myer, Eric P. Zorrilla · 2024 · Cells
  18. Could immunotherapy be a hope for addiction treatment?
    Maria Carolina Machado da Silva, Luiz Philipe de Souza Ferreira, Amanda Della Giustina · 2024 · Clinics
  19. Drug Repurposing Patent Applications January–March 2015
    Hermann AM Mucke · 2015 · Assay and Drug Development Technologies
  20. Effects of entinostat, quisinostat, and tubastatin-A on alcohol consumption in male high ethanol consuming rats
    Sheketha R. Hauser, Laura B. Ferguson, Tiebing Liang, Erin Jarvis, Roy Dayne Mayfield, Richard L. Bell · 2025 · Frontiers in Epigenetics and Epigenomics
  21. Neuroglia in substance use disorders
    Emily M. Castro, Shahrdad Lotfipour, Frances M. Leslie · 2025 · Handbook of clinical neurology
  22. Ibudilast attenuates the association between pain intensity and heavy drinking in alcohol use disorder: A secondary analysis of a randomized clinical trial
    Steven J. Nieto, Erica N. Grodin, Lara A. Ray · 2025 · Alcohol
  23. Childhood trauma and the prevalence of alcohol dependence in adulthood
    Karolina Kosecka, Ewa Stelmach · 2020 · Current Problems of Psychiatry
  24. Mesenchymal stem cells as a promising therapy for alcohol use disorder
    Javiera Gallardo, Pablo Berríos‐Cárcamo, Fernando E. Ezquer · 2024 · International review of neurobiology
  25. Neuromolecular and behavioral effects of ethanol deprivation in Drosophila
    Natalie M. D’Silva, Katie S. McCullar, Ashley Mae Conard, Tyler Blackwater, Reza Azanchi, Ulrike Heberlein, Erica Larschan, Karla R. Kaun · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Pituitary adenylate cyclase-activating polypeptide regulates excessive alcohol consumption
    Andrew Kim · 2015 · OpenBU (Boston University)
  27. Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity
    Joshua C. Gray, Mikela A. Murphy, Lorenzo Leggio · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Alcohol
    2021 · Elsevier eBooks
  29. Brain-Immune Mechanisms in Alcohol Use Disorder Targeting Neuroimmune Signaling in Alcohol Use Disorder: Opportunities for Translation
    Erica N. Grodin, Lindsay R. Meredith, Elizabeth M. Burnette, Lara A. Ray · 2023 · Springer eBooks
  30. Drug Repurposing Patent Applications: January–March 2015
    Hermann AM Mucke · 2015 · Drug Repurposing Rescue and Repositioning
  31. Ibudilast perpetuates stress-induced anxiety-like behavior and fear memory expression in adult Sprague-Dawley rats
    Rachel M. Enga, Aurian O. Naderi, Emily M. Scott, Kilana D. Coachman, Gabriella M. Silva, Elizabeth M. Bergman, Matthew D. May, Andrew Batuure, Nicole S Fenlon, James C. DeMar et al. · 2025 · Journal of Pharmacology and Experimental Therapeutics
  32. Proteomic analysis of central amygdala systems regulated by mifepristone in the context of alcohol dependence
    Sumin Lee, Laura Monteagudo Romero, John W. Lammons, Jennifer M. Klein, Kimberly N. Edwards, Jessie J. Guidry, Scott Edwards · 2025 · Neuropharmacology
  33. Additional file 2 of Ibudilast for alcohol use disorder: study protocol for a phase II randomized clinical trial
    Elizabeth M. Burnette, Baskerville, Wave-Ananda, Erica N. Grodin, Lara A. Ray · 2020 · Figshare
  34. Additional file 1 of Ibudilast for alcohol use disorder: study protocol for a phase II randomized clinical trial
    Elizabeth M. Burnette, Baskerville, Wave-Ananda, Erica N. Grodin, Lara A. Ray · 2020 · Figshare
  35. Identifying drug targets for schizophrenia through gene prioritization
    Julia Kraft, Alice Braun, Swapnil Awasthi, Georgia Panagiotaropoulou, Marijn Schipper, Nathaniel Bell, Daniëlle Posthuma, Antonio F. Pardiñas, Stephan Ripke, Karl Heilbron · 2026 · Translational Psychiatry
  36. Reductions in cigarette and cannabis use during a randomized clinical trial for alcohol use disorder
    Malia A. Belnap, Kaitlin R. McManus, Dylan E. Kirsch, Erica N. Grodin, Lara A. Ray · 2026 · Alcohol and Alcoholism
  37. Microglial activation and neuroinflammation: implications for neuropsychiatric symptoms
    Taslim Uddin, Chandrima Halder, Afia Asma, Anika Zaheen, Azrin Nahian, Rhea Sarkar Nipun, Jannatul Ferdous, Rakhee Sarker, Maisha Maliha Misha, Sadia Tasnim et al. · 2026 · Exploration of Neuroprotective Therapy
  38. Research advances in the mechanisms of neuroinflammatory in substance addiction
    Jiahui ZHOU, Zhiting Zou, Tonghe Pan, Yu LIU · 2026 · Journal of Zhejiang University (Medical Sciences)