Cited by 86Cannabis and Cannabinoid ResearchSubstance Abuse Treatment and OutcomesOpioid Use Disorder Treatment

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The association between recreational cannabis legalization, commercialization and cannabis‐attributable emergency department visits in Ontario, Canada: an interrupted time–series analysis

Abstract

Background and aims: Recreational cannabis was legalized in Canada in October 2018. Initially, the Government of Ontario (Canada’s largest province) placed strict limits on the number of cannabis retail stores before later removing these limits. This study measured changes in cannabis‐attributable emergency department (ED) visits over time, corresponding to different regulatory periods. Design: Interrupted time–series design using population‐level data. Two policy periods were considered; recreational cannabis legalization with strict store restrictions (RCL, 17 months) and legalization with no store restrictions [recreational cannabis commercialization (RCC), 15 months] which coincided with the COVID‐19 pandemic. Segmented Poisson regression models were used to examine immediate and gradual effects in each policy period. Setting: Ontario, Canada. Participants: All individuals aged 15–105 years (n = 13.8 million) between January 2016 and May 2021. Measurements: Monthly counts of cannabis‐attributable ED visits per capita and per all‐cause ED visits in individuals aged 15+ (adults) and 15–24 (young adults) years. Findings: We observed a significant trend of increasing cannabis‐attributable ED visits pre‐legalization. RCL was associated with a significant immediate increase of 12% [incident rate ratio (IRR) = 1.12, 95% confidence interval (CI) = 1.02–1.23] in rates of cannabis‐attributable ED visits followed by significant attenuation of the pre‐legalization slope (monthly slope change IRR = 0.98, 95% CI = 0.97–0.99). RCC and COVID‐19 were associated with immediate significant increases of 22% (IRR = 1.22, 95% CI = 1.09–1.37) and 17% (IRR = 1.17, 95% CI = 1.00–1.37) in rates of cannabis‐attributable visits and the proportion of all‐cause ED visits attributable to cannabis, respectively, with insignificant increases in monthly slopes. Similar patterns were observed in young adults. Conclusions: In Ontario, Canada, cannabis‐attributable emergency department visits stopped increasing over time following recreational cannabis legalization with strict retail controls but then increased during a period coinciding with cannabis commercialization and the COVID‐19 pandemic.

Overview

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Crossref · 10.1111/add.15834

Cites

3 of 3 references verified0 citation errors · 0 not checkable

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  • The monthly rate of cannabis-attributable ED visits was increasing before legalization, but there was a statistically significant 18% decline in the monthly rate 17 months after legalization with strict retail control (February 2020).

    “The monthly rate of cannabis‐attributable ED visits was increasing before legalization, but there was a statistically significant 18% decline in the monthly rate 17 months after legalization with strict retail control (February 2020)”
  • In all time-periods, people aged 15-24 years had a higher rate of cannabis-attributable ED visits than older age groups.

    “In all time‐periods, people aged 15–24 years had a higher rate of cannabis‐attributable visits than older age groups.”
  • When data for the first 2 months of COVID-19 were excluded, cannabis-attributable ED visits significantly increased by 22% after commercialized retail sales compared to the period when strict retail store controls were in place.

    “When data for these 2 months were excluded, cannabis‐attributable ED visits significantly increased by 22% after commercialized retail sales compared to the period when strict retail store controls were in place.”
  • Cannabis-attributable ED visits decreased during the first 2 months of the COVID-19 pandemic because of lower than usual ED use.

    “Cannabis‐attributable ED visits decreased during the first 2 months of the COVID‐19 pandemic because of lower than usual ED use.”

Citations

Cites

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Research works printed but not linked: 26

  1. Centre for Addiction and Mental Health (CAMH), 2014, Cannabis Policy Framework
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  4. Statistics Canada, 2018, Analysis in Brief. The Retail Cannabis Market in Canada: a Portrait of the First Year
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  20. Government of Canada, 2021, Canadian Cannabis Survey 2020: Summary
  21. Cannabis Use During the COVID‐19 Pandemic in Canada: A Repeated Cross‐sectional Study. PubMed [internet] [cited 2021 Jun 22]. Available at:https://pubmed.ncbi.nlm.nih.gov/33323693/
  22. Baraniecki R, 2021, Acute cannabis intoxication in the emergency department: the effect of legalization, BMC Emerg Med [internet], 21
  23. Auger N, 2020, Cannabis‐related hospitalizations among youth in Canada before and after cannabis legalization, J Addict Med [internet]
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  25. Alcohol and Gaming Commission of Ontario (AGCO), 2021, Status of Current Cannabis Retail Store Applications
  26. Shadish WR, 2002, Experimental and Quasi‐Experimental Designs for Generalized Causal Inference

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Metadata

Authors
Myran, D. T., Pugliese, M., Tanuseputro, P., Cantor, N., Rhodes, E., & Taljaard, M.
Affiliations
  • University of Ottawa (CA)
  • Institute for Clinical Evaluative Sciences (CA)
  • Ottawa Hospital Research Institute (CA)
Corresponding author
Myran, Daniel T.
Venue
Addiction
Publisher
Wiley
Published
2022-02-17
Volume
117
Issue
7
Pages
1952-1960
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W4212945528
Cited by
86
References
3
Citations by year
2026: 8 · 2025: 17 · 2024: 23 · 2023: 29 · 2022: 9
FWCI
11.67
Type
journal article
Language
en
Open access
closed
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
Funders
Institute of Population and Public Health (452360)
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
recreational cannabis legalization, cannabis commercialization, emergency department utilization, cannabis policy, COVID-19 pandemic, young adults, cannabis harm
MeSH terms
COVID-19, Canada, Cannabis, Carcinoma, Renal Cell, Emergency Service, Hospital, Humans, Kidney Neoplasms, Legislation, Drug, Ontario, Young Adult, Pandemics

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