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Cited by 630

The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.

EAACI guidelines: Anaphylaxis (2021 update)

Open access
Muraro, Antonella, Worm, Margitta, Alviani, Cherry, Cardona, Victoria, DunnGalvin, Audrey, Garvey, Lene Heise, Riggioni, Carmen, de Silva, Debra, Angier, Elizabeth, Arasi, Stefania, Bellou, Abdelouahab, Beyer, Kirsten, Bijlhout, Diola, Bilò, Maria Beatrice, Bindslev‐Jensen, Carsten, Brockow, Knut, Fernandez‐Rivas, Montserrat, Halken, Susanne, Jensen, Britt, Khaleva, Ekaterina, Michaelis, Louise J., Oude Elberink, Hanneke N. G., Regent, Lynne, Sanchez, Angel, Vlieg‐Boerstra, Berber J., Roberts, Graham, European Academy of Allergy and Clinical Immunology, Food Allergy, Anaphylaxis Guidelines Group·2022·Allergy

Abstract

Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognize and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer‐reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first‐line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritize clinical trials with the potential to improve the management of patients at risk of anaphylaxis.

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Metadata

Authors
Muraro, A., Worm, M., Alviani, C., Cardona, V., DunnGalvin, A., Garvey, L. H., Riggioni, C., de Silva, D., Angier, E., Arasi, S., Bellou, A., Beyer, K., Bijlhout, D., Bilò, M. B., Bindslev‐Jensen, C., Brockow, K., Fernandez‐Rivas, M., Halken, S., Jensen, B., Khaleva, E., Michaelis, L. J., Oude Elberink, H. N. G., Regent, L., Sanchez, A., Vlieg‐Boerstra, B. J., Roberts, G., & European Academy of Allergy and Clinical Immunology, F. A.
Venue
Allergy
Publisher
Wiley
Published
2021-09
Volume
77
Issue
2
Pages
357-377
ISSN
  • 0105-4538 (ISSN-L)
  • 1398-9995
OpenAlex
W3192902361
Cited by
630
References
85
FWCI
55.58
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: EAACI guidelines: Anaphylaxis (2021 update). https://app.cochat.ai/papers/10.1111/all.15032
The paper
Muraro, A., Worm, M., Alviani, C., Cardona, V., DunnGalvin, A., Garvey, L. H., Riggioni, C., de Silva, D., Angier, E., Arasi, S., Bellou, A., Beyer, K., Bijlhout, D., Bilò, M. B., Bindslev‐Jensen, C., Brockow, K., Fernandez‐Rivas, M., Halken, S., Jensen, B., . . . European Academy of Allergy and Clinical Immunology, F. A. (2022). EAACI guidelines: Anaphylaxis (2021 update). Allergy. https://doi.org/10.1111/all.15032

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.