Dietary administration of astaxanthin improves feed utilization, growth performance and survival of Asian seabass,Lates calcarifer(Bloch, 1790)
Open accessAbstract
This study was undertaken to assess the impacts of dietary astaxanthin supplementation on growth performance, feed utilization, survival, and serum growth hormone (GH) availability of Asian seabass, Lates calcarifer, with special reference to dose–response relationships and variations during different feeding phases (short-term, medium-term and long-term). Fish were fed the following diets in triplicate for 90 days: the control (CD), AX50 (50 mg astaxanthin/kg diet), AX100 (100 mg astaxanthin/kg diet) and AX150 (150 mg astaxanthin/kg diet). The findings revealed that fish exhibited significant linear increments (p < .05) in specific growth rate (SGR), weight gain, feed utilization efficiency and survival when fed various diets with escalating levels of astaxanthin. Supplementation with dietary astaxanthin significantly augmented (p < .05) GH levels in fish. Significant positive associations (p < .05) were observed between circulating serum GH levels and SGR of fish from all groups following three consecutive feeding phases, denoting a robust cause-and-effect relationship. Circulating GH concentrations were considered as a sensitive biomarker of growth performance in Asian seabass. This study illustrated that supplemental astaxanthin could be administered in culture protocols to improve the growth rate and commercial hatchery production of Asian seabass, and possibly other teleost species.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Astaxanthin has been approved as a colour additive in fish feeds and as a dietary supplement for human consumption, with an advised daily intake of 0.034 mg/kg body weight.
“ASX has also been approved as a colour additive in fish feeds and as a dietary supplement for human consumption, with an advised daily intake of 0.034 mg · kg -1 body weight [67].”
From Key Targets for Improving Algal Biofuel Production (2021) · cites this paper as [67]
The Introduction describes astaxanthin as a pigment used by aquatic animals, and Section 2.2 describes adding it to experimental fish feed. Searches for approval, human dietary supplements, and 0.034 mg/kg body weight found no passage addressing those claims; the paper’s recommended feed doses concern Asian seabass, not human intake. Page numbers were not available in our copy. (LLM, conf=0.76)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
(2023) · Oxford University Press eBooks · doi:10.1093/9780197610145.002.001 · Cited by 28,120 · see citing works
Glencross, B. D., Booth, M. A., & Allan, G. L. (2007) · Aquaculture Nutrition · doi:10.1111/j.1365-2095.2007.00450.x · Cited by 812 · see citing works
Microalgae as versatile cellular factories for valued products
Koller, M., Muhr, A., & Braunegg, G. (2014) · Algal Research · doi:10.1016/j.algal.2014.09.002 · Cited by 639 · see citing works
Fish immune system and its nutritional modulation for preventive health care
Kiron, V. (2012) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2011.12.015 · Cited by 600 · see citing works
Astaxanthin from Microbial Sources
Johnson, E. A., & An, G.-H. (1991) · Critical Reviews in Biotechnology · doi:10.3109/07388559109040622 · Cited by 509 · see citing works
Astaxanthin as feed supplement in aquatic animals
Lim, K. C., Yusoff, F. M., Shariff, M., & Kamarudin, M. S. (2017) · Reviews in Aquaculture · doi:10.1111/raq.12200 · Cited by 460 · see citing works
Self-citationOntogeny of osmoregulation in postembryonic fish: A review
Varsamos, S., Lorin‐Nebel, C., & Charmantier, G. (2005) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpb.2005.01.013 · Cited by 423 · see citing works
Availability and Utilization of Pigments from Microalgae
Begum, H., Yusoff, F. M., Banerjee, S., Khatoon, H., & Shariff, M. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.764841 · Cited by 380 · see citing works
Self-citationProlactin and growth hormone in fish osmoregulation
Sakamoto, T., & McCormick, S. D. (2006) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2005.10.008 · Cited by 376 · see citing works
Matsuno, T. (2001) · Fisheries Science · doi:10.1046/j.1444-2906.2001.00323.x · Cited by 375 · see citing works
Lugert, V., Thaller, G. E., Tetens, J., Schulz, C., & Krieter, J. (2014) · Reviews in Aquaculture · doi:10.1111/raq.12071 · Cited by 349 · see citing works
The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge
Volkoff, H. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00540 · Cited by 345 · see citing works
Reindl, K. M., & Sheridan, M. A. (2012) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2012.08.003 · Cited by 288 · see citing works
Growth Hormone Endocrinology of Salmonids: Regulatory Mechanisms and Mode of Action
Björnsson, B. T., Johansson, V., Benedet, S., et al. (2002) · Fish Physiology and Biochemistry · doi:10.1023/b:fish.0000032728.91152.10 · Cited by 224 · see citing works
Pérez‐López, P., González‐García, S., Jeffryes, C. S., Agathos, S. N., McHugh, E., Walsh, D., Murray, P., Moane, S., Feijóo, G., & Moreira, M. T. (2013) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2013.07.011 · Cited by 219 · see citing works
Young, G., Björnsson, B. T., Prunet, P., et al. (1989) · General and Comparative Endocrinology · doi:10.1016/s0016-6480(89)80029-2 · Cited by 203 · see citing works
Misuse of multiple comparison tests and underuse of contrast procedures in aquaculture publications
Yossa, R., & Verdegem, M. C. J. (2014) · Aquaculture · doi:10.1016/j.aquaculture.2014.12.023 · Cited by 194 · see citing works
Kalinowski, C. T., Robaina, L., Fernández-Palacios, H., Schuchardt, D., & Izquierdo, M. S. (2004) · Aquaculture · doi:10.1016/j.aquaculture.2004.11.001 · Cited by 186 · see citing works
Wang, Y.-J., Chien, Y., & Pan, C. (2006) · Aquaculture · doi:10.1016/j.aquaculture.2006.08.040 · Cited by 180 · see citing works
Davis, M. J. (2021) · Journal of Data Science · doi:10.6339/jds.2010.08(1).563 · Cited by 173 · see citing works
Datta, S. N., Kaur, V. I., Dhawan, A., et al. (2013) · SpringerPlus · doi:10.1186/2193-1801-2-436 · Cited by 152 · see citing works
Liu, Y., Wu, J., & Ho, K.-P. (2005) · Biochemical Engineering Journal · doi:10.1016/j.bej.2005.08.031 · Cited by 151 · see citing works
Li, M., Wu, W., PiaoPing, Z., Xie, F., Zhou, Q., & Mai, K. (2014) · Aquaculture · doi:10.1016/j.aquaculture.2014.08.022 · Cited by 150 · see citing works
Inbaraj, B. S., Chien, J. T., & Chen, B. (2005) · Journal of Chromatography A · doi:10.1016/j.chroma.2005.10.055 · Cited by 141 · see citing works
Stefansson, S. O., Bjömsson, B. T., Hansen, T., et al. (1991) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/f91-249 · Cited by 137 · see citing works
Biology and Culture of Asian Seabass Lates Calcarifer
Jerry, D. R. (2013) · CRC Press eBooks · doi:10.1201/b15974 · Cited by 131 · see citing works
Devlin, R. H., Sakhrani, D., Tymchuk, W. E., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809798106 · Cited by 127 · see citing works
Advances by Selective Breeding for Aquatic Species: A Review
Gjedrem, T., & Robinson, N. (2014) · Agricultural Sciences · doi:10.4236/as.2014.512125 · Cited by 124 · see citing works
Pigmentation of rainbow trout from start feeding to sexual maturation
Bjerkeng, B., Storebakken, T., & Liaaen‐Jensen, S. (1992) · Aquaculture · doi:10.1016/0044-8486(92)90117-4 · Cited by 114 · see citing works
Baker, R. T. M., Pfeiffer, A. M., Schöner, F. J., et al. (2002) · Animal Feed Science and Technology · doi:10.1016/s0377-8401(02)00116-5 · Cited by 111 · see citing works
Tejera, N., Cejas, J. R., Rodríguez, C., Bjerkeng, B., Jerez, S., Bolaños, A., & Lorenzo, A. (2007) · Aquaculture · doi:10.1016/j.aquaculture.2007.01.019 · Cited by 110 · see citing works
Rahman, M. M., Khosravi, S., Chang, K. H., & Lee, S. (2016) · Preventive Nutrition and Food Science · doi:10.3746/pnf.2016.21.3.281 · Cited by 109 · see citing works
Growth hormone and fish immune system
Yada, T. (2007) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2007.01.045 · Cited by 108 · see citing works
The Nutrition of the Young Ayrshire Calf
Blaxter, K. L., & Wood, W. A. (1952) · British Journal Of Nutrition · doi:10.1079/bjn19520001 · Cited by 108 · see citing works
Cheng, C.-H., Guo, Z., Ye, C., & Wang, A. (2017) · Fish Physiology and Biochemistry · doi:10.1007/s10695-017-0425-5 · Cited by 106 · see citing works
Thangarathinam, R., Sampath, K., Vasudevan, I., & James, R. (2006) · Israeli Journal of Aquaculture - Bamidgeh · doi:10.46989/001c.20433 · Cited by 102 · see citing works
Gomes, E., Dias, J. P., Silva, P., Valente, L. M. P., Empis, J., Gouveia, L., Bowen, J., & Young, A. J. (2002) · European Food Research and Technology · doi:10.1007/s00217-001-0475-9 · Cited by 100 · see citing works
Christiansen, R., Lie, Ø. H., & Torrissen, O. J. (1995) · Aquaculture Nutrition · doi:10.1111/j.1365-2095.1995.tb00043.x · Cited by 98 · see citing works
Pham, M. A., Byun, H., Kim, K., & Lee, S. (2014) · Aquaculture · doi:10.1016/j.aquaculture.2014.04.019 · Cited by 97 · see citing works
Heide, A., Foss, A., Stefansson, S. O., et al. (2006) · Aquaculture · doi:10.1016/j.aquaculture.2006.06.050 · Cited by 84 · see citing works
Growth Hormone Increases Aggressive Behavior in Juvenile Rainbow Trout
Jönsson, E., Johnsson, J. I., & Björnsson, B. T. (1998) · Hormones and Behavior · doi:10.1006/hbeh.1997.1426 · Cited by 83 · see citing works
Enhanced production of astaxanthin by flashing light using Haematococcus pluvialis
Kim, Z., Kim, S.-H., Lee, H.-S., & Lee, C. (2006) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2005.11.041 · Cited by 82 · see citing works
Neuroendocrine regulation of somatic growth in fishes
Dai, X., Zhang, W., Zhuo, Z., et al. (2015) · Science China Life Sciences · doi:10.1007/s11427-015-4805-8 · Cited by 80 · see citing works
Sawanboonchun, J., Roy, W. J., Robertson, D. A., et al. (2008) · Aquaculture · doi:10.1016/j.aquaculture.2008.06.024 · Cited by 72 · see citing works
Pérez‐Sánchez, J., Martí-Palanca, H., & Bail, P. Y. L. (1994) · Fish Physiology and Biochemistry · doi:10.1007/bf00004358 · Cited by 72 · see citing works
Björnsson, B. T., Stefansson, S. O., & Hansen, T. (1995) · General and Comparative Endocrinology · doi:10.1006/gcen.1995.1135 · Cited by 71 · see citing works
Hallerman, E. M., McLean, E., & Fleming, I. (2006) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2006.09.008 · Cited by 68 · see citing works
Kalinowski, C. T., Robaina, L., & Izquierdo, M. S. (2010) · Aquaculture International · doi:10.1007/s10499-010-9401-0 · Cited by 65 · see citing works
Hansen, Ø. J., Puvanendran, V., & Bangera, R. (2014) · Aquaculture Research · doi:10.1111/are.12540 · Cited by 63 · see citing works
Heritability of growth traits in the Asian seabass ( Lates calcarifer )
Ye, B., Wan, Z., Wang, L., Pang, H., Wen, Y., Liu, H., Liang, B., Lim, H. S., Jiang, J., & Yue, G. H. (2017) · Aquaculture and Fisheries · doi:10.1016/j.aaf.2017.06.001 · Cited by 63 · see citing works
Ytrestøyl, T., Struksnæs, G., Koppe, W., et al. (2005) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2005.09.004 · Cited by 60 · see citing works
Christiansen, R., Lie, Ø. H., & Torrissen, O. J. (1994) · Aquaculture Research · doi:10.1111/j.1365-2109.1994.tb01352.x · Cited by 57 · see citing works
Endocrine and Local IGF-I in the Bony Fish Immune System
Franz, A.-C., Faass, O., Köllner, B., et al. (2016) · Biology · doi:10.3390/biology5010009 · Cited by 53 · see citing works
Ayoade, A. A. (2011) · Journal of Fisheries and Aquatic Science · doi:10.3923/jfas.2011.472.478 · Cited by 48 · see citing works
Chapter 4 Growth Hormone Regulation in Fish
Chang, J. P., & Wong, A. (2009) · Fish physiology · doi:10.1016/s1546-5098(09)28004-6 · Cited by 42 · see citing works
Bazyar Lakeh, A. A., Ahmadi, M. R., Safi, S., Ytrestøyl, T., & Bjerkeng, B. (2010) · Journal of Applied Ichthyology · doi:10.1111/j.1439-0426.2009.01349.x · Cited by 41 · see citing works
Xie, J.-J., Chen, X., Niu, J., et al. (2017) · Fisheries and aquatic sciences · doi:10.1186/s41240-017-0052-1 · Cited by 37 · see citing works
Effects of various dietary factors on astaxanthin absorption in Atlantic salmon ( Salmo salar )
Chimsung, N., Tantikitti, C., Milley, J. E., et al. (2012) · Aquaculture Research · doi:10.1111/are.12108 · Cited by 31 · see citing works
Channel Catfish, Ictalurus punctatus, Size and Feed Conversion Ratio
Robinson, E. H., & Li, M. H. (2010) · Journal of the World Aquaculture Society · doi:10.1111/j.1749-7345.2010.00426.x · Cited by 30 · see citing works
Abolfathi, M., Hajimoradloo, A., Ghorbani, R., et al. (2012) · Journal of Fish Biology · doi:10.1111/j.1095-8649.2012.03407.x · Cited by 30 · see citing works
Palma, J., Andrade, J. P., & Bureau, D. (2016) · Aquaculture Nutrition · doi:10.1111/anu.12394 · Cited by 30 · see citing works
Glencross, B. D., Blyth, D., Irvin, S. J., et al. (2014) · Aquaculture Nutrition · doi:10.1111/anu.12111 · Cited by 26 · see citing works
Senanan, W., Pechsiri, J., Sonkaew, S., et al. (2014) · Aquaculture Research · doi:10.1111/are.12442 · Cited by 21 · see citing works
Joerakate, W., Yenmak, S., Senanan, W., et al. (2018) · Agriculture and Natural Resources · doi:10.1016/j.anres.2018.05.015 · Cited by 21 · see citing works
Pituitary and plasma growth hormone dynamics during sexual maturation of female Atlantic salmon
Benedet, S., Andersson, E., Mittelholzer, C., et al. (2010) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2010.02.011 · Cited by 19 · see citing works
Castillo-Vargasmachuca, S. G., Ponce‐Palafox, J. T., Arámbul‐Muñoz, E., et al. (2016) · Reviews in Aquaculture · doi:10.1111/raq.12166 · Cited by 19 · see citing works
Effects of Acute Handling Stress on Expression of Growth‐Related Genes in Pampus argenteus
Sun, P., Yin, F., & Tang, B. (2016) · Journal of the World Aquaculture Society · doi:10.1111/jwas.12323 · Cited by 19 · see citing works
Cao, H., Zhou, R., Wei, Q., et al. (2011) · Journal of Applied Ichthyology · doi:10.1111/j.1439-0426.2010.01665.x · Cited by 18 · see citing works
Cho, S. H. (2012) · Fisheries and aquatic sciences · doi:10.5657/fas.2012.0069 · Cited by 13 · see citing works
Asker, D., Awad, T. S., Beppu, T., & Uéda, K. (2012) · Methods in molecular biology · doi:10.1007/978-1-61779-879-5_4 · Cited by 10 · see citing works
Wang, X. M., Gao, J., Xu, M., et al. (2017) · AquaDocs (United Nations Educational, Scientific and Cultural Organization) · doi:10.22092/ijfs.2018.114690 · Cited by 7 · see citing works
Khalil, N. A., & Mousa, M. A. (2013) · The Egyptian Journal of Aquatic Research · doi:10.1016/j.ejar.2013.03.002 · Cited by 5 · see citing works
Gjedrem, T., & Baranski, M. (2009) · Reviews: methods and technologies in fish biology and fisheries · doi:10.1007/978-90-481-2773-3_5 · Cited by 3 · see citing works
Weber, G. M., Davidson, J., Kenney, P. B., et al. (2015) · North American Journal of Aquaculture · doi:10.1080/15222055.2014.987933 · Cited by 3 · see citing works
Qiang, J., Yang, H., Wang, H., et al. (2012) · Dongwu yingyang xuebao · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Chang, J. P., & Wong, A. O. L. (2009). Growth hormone regulation in fish: A multifactorial model with hypothalamic, peripheral and local auto- crine/paracrine signals. In N. J. Bernier, G. Van DerKraak, A. P. Farrell, & C. J. Brauner (Eds.), Fish neuroendocrinology (vol. 28, pp. 151-195). Cambridge, MA: Academic Press.
- Niu, J., Li, C. H., Liu, Y. J., Tian, L. X., Chen, X., Huang, Z., & Lin, H. Z. (2011). Dietary values of astaxanthin and canthaxanthin in Penaeus monodon in the presence and absence of cholesterol supplementa- tion: Effect on growth, nutrient digestibility and tissue carotenoid composition. British Journal of Nutrition, 6, 1-12.
Cited by
Sorted by citations
Oslan, S. N. H., Shoparwe, N. F., Yusoff, A. H., Rahim, A. A., Chang, C. S., Tan, J. S., Oslan, S. N., Arumugam, K., Ariff, A. B., Sulaiman, A. Z., et al. (2021) · Biomolecules · doi:10.3390/biom11020256 · Cited by 215 · see citing works
Key Targets for Improving Algal Biofuel Production
Griffiths, G., Hossain, A. K., Sharma, V., & Duraisamy, G. (2021) · Clean Technologies · doi:10.3390/cleantechnol3040043 · Cited by 49 · see citing works
- Authors
- Lim, K. C., Yusoff, F. M., Shariff, M., & Kamarudin, M. S.
- Affiliations
- Universiti Putra Malaysia (MY)
- Corresponding author
- Yusoff, Fatimah Md.
- Venue
- Aquaculture Nutrition
- Publisher
- Wiley
- Published
- 2019-08-18
- Volume
- 25
- Issue
- 6
- Pages
- 1410-1421
- ISSN
- 1353-5773 (ISSN-L)
- 1365-2095
- OpenAlex
- W2969389287
- Cited by
- 33
- References
- 75
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 5 · 2023: 2 · 2022: 7 · 2021: 5 · 2020: 1 · 2019: 1
- FWCI
- 3.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Aquaculture Nutrition (publishedVersion)
- Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) (acceptedVersion)
- Funders
- Universiti Putra Malaysia (GP-IPS/2014/9433901)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Keywords
- astaxanthin, Lates calcarifer, dietary supplementation, growth performance, feed efficiency, survival, growth hormone, serum growth hormone, specific growth rate, dose-response relationship, fish feed additives, hatchery production
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
