Community guidelines for GPCR ligand bias: IUPHAR review 32

Cited by (234)

Items 101–200 of 234

1. Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies
   Aurélien Fouillen, Pierre Couvineau, Gérald Gaibelet, Stéphanie Riché, Hélène Orcel, Christiane Mendre, Ali Kanso, Romain Lanotte, Julie Nguyen, Juliette Dimon et al. · 2024 · Computational and Structural Biotechnology Journal
2. High-affinity ELR+ chemokine ligands show G protein bias over β-arrestin recruitment and receptor internalization in CXCR1 signaling
   Katrijn Boon, Nathan Vanalken, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy · 2024 · Journal of Biological Chemistry
3. Improved Split TEV GPCR β-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and β-arrestin Binding Motif Variants
   Yuxin Wu, Isabelle von Hauff, Niels Jensen, Moritz J. Rossner, Michael C. Wehr · 2022 · Biosensors
4. Functional selectivity of EM-2 analogs at the mu-opioid receptor
   Justyna Piekielna‐Ciesielska, Davide Malfacini, Francine Medjiofack Djeujo, Chantal Marconato, Karol Wtorek, Girolamo Calò, Anna Ewa Janecka · 2023 · Frontiers in Pharmacology
5. Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo
   Agnieszka Olejarz‐Maciej, Szczepan Mogilski, Tadeusz P. Karcz, Tobias Werner, Katarzyna Kamińska, Jarosław Kupczyk, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Holger Stark, Katarzyna Kieć‐Kononowicz et al. · 2023 · Molecules
6. Insights into the operational model of agonism of receptor dimers
   Ján Jakubík, Alena Randáková · 2022 · Expert Opinion on Drug Discovery
7. Novel Fluorescently Labeled PACAP and VIP Highlight Differences between Peptide Internalization and Receptor Pharmacology
   Tyla I. Alexander, Zoe Tasma, Andrew Siow, Tayla A. Rees, Margaret Anne Brimble, Paul W. R. Harris, Debbie L. Hay, Christopher S. Walker · 2022 · ACS Pharmacology & Translational Science
8. Probing phosphorylation events in biological membranes: The transducer function
   Daniel Wirth, Ece Özdemir, Kalina A. Hristova · 2024 · Biochimica et Biophysica Acta (BBA) - Biomembranes
9. Deletion of arrestin-3 does not reduce drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration
   Sarah Warren Gooding, Lindsey C. Felth, Randi L. Foxall, Zachary Rosa, Kyle E. Ireton, Izabella Sall, Joshua Gipoor, Anirudh Gaur, Madeline King, Noah Dirks et al. · 2024 · Frontiers in Pharmacology
10. Chemically Induced Dimerization via Nanobody Binding Facilitates in Situ Ligand Assembly and On-Demand GPCR Activation
    Shubhra Jyoti Saha, Ross W. Cheloha · 2024 · JACS Au
11. Differential association of EphA2 intracellular regions in biased signaling
    Elmer A. Zapata-Mercado, Randall R Rainwater, Ece Özdemir, Evgenia V Azarova, Mateusz Adam Krzyścik, Elena Bianca Pasquale, Kalina A. Hristova · 2025 · Journal of Biological Chemistry
12. Structure–Signal Relationships of the δ-Opioid-Receptor (DOR)-Selective Agonist KNT-127—Part I: Impact of the Morphinan Skeleton on the G-Protein-Biased DOR Agonism
    Keita Kajino, Tomoya Sugai, Ryoji Kise, Riko Suzuki, Akihisa Tokuda, Yuki Sekiya, Tomoya Kakumoto, Risako Katamoto, Noriki Kutsumura, Yasuyuki Nagumo et al. · 2025 · Chemical and Pharmaceutical Bulletin
13. Impact of G protein-coupled receptor conformation on signaling bias: Integrating simulations and biophysical experiments
    Gian Marco Elisi, Giovanni Bottegoni · 2025 · Pharmacology & Therapeutics
14. The many facets of biased signaling: Mechanisms and possible therapeutic implications
    Karina Helivier Solís, María Teresa Romero‐Ávila, Rocío Alcántara-Hernández, Jesús Adolfo García-Sáinz · 2025 · Pharmacology & Therapeutics
15. Biophysical Dissection of Isolated GPCRs: The Adenosine A2A Receptor under the Bistouries
    Jean‐Louis Banères, Thomas Botzanowski, Jean Albert Boutin, Barbara Calamini, J.-G. Castel, Laurent J. Catoire, Sarah Cianférani, Claire Demesmay, Gavin Ferguson, Gilles Ferry et al. · 2023 · Receptors
16. In‐Cell Arrestin‐Receptor Interaction Assays
    Chen Zheng, Jonathan A. Javitch, Nevin A. Lambert, Prashant Donthamsetti, Vsevolod V. Gurevich · 2023 · Current Protocols
17. How Ligands Achieve Biased Signaling toward Arrestins
    Qianru Jiang, Tao Che · 2025 · Biochemistry
18. Therapeutic exploration of biased ligands at class A G protein-coupled receptors over the past 20 years
    Jixia Wang, Fangfang Xu, Yanfang Liu, Han Zhou, Wenjie Yuan, Fan Liu, Fang Ye, Xinmiao Liang · 2025 · Pharmacology & Therapeutics
19. Unraveling allosteric signaling of G protein-coupled receptors (GPCRs) by single-molecule fluorescence
    Michael Tope Agbadaola, Daniel Hilger, Sandro Keller, Georg Krainer · 2025 · Biophysical Reviews
20. Endogenous forms of ATP–ATP 4− and MgATP 2− —orchestrate distinct pathophysiological signaling via biased activation of P2X3 receptors
    Jin Qiang Wang, Li Guan, Tingting Wang, Tang-Xuan Xie, Yi-Yu Lin, Mengyang Sun, Dongping Wang, Xue Zhang, Yu-Jing Bian, Chen-Xi Yue et al. · 2025 · Proceedings of the National Academy of Sciences
21. Molecular mechanism of β-arrestin 2 interaction with phosphorylated intracellular loop 3 of dopamine receptor D2
    Kiae Kim, Jeong Seok Ji, Hee Ryung Kim, Yoonjung Choi, Hyung Ho Lee, Asuka Inoue, Ka Young Chung · 2025 · Communications Biology
22. In vitro pharmacological activity of twenty-eight synthetic cannabinoid receptor agonists at the type 1 and 2 cannabinoid receptors
    Géraldine Mercier, Kawthar A. Mohamed, Ayat Zagzoog, Laura Cropper, Brendan Ritchie, Zhiyun Jin, Mikin Patel, Robert B. Laprairie · 2025 · Neurochemistry International
23. The Ca2+/CaM, Src kinase and/or PI3K-dependent EGFR transactivation via 5-HT2A and 5-HT1B receptor subtypes mediates 5-HT-induced vasoconstriction
    Şahika Güner, Tamila Akhayeva, Charles David Nichols, Hakan Gürdal · 2022 · Biochemical Pharmacology
24. Why Search for Alternative GPCR Agonists?
    Jean Albert Boutin, Jérôme Leprince · 2023 · Receptors
25. How New Developments in Pharmacology Receptor Theory Are Changing (Our Understanding of) Hypertension Therapy
    Stephanie Wengert Watts, Raymond R. Townsend, Richard R. Neubig · 2023 · American Journal of Hypertension
26. Serotonin 5-HT1A receptor biased agonists: The challenge of translating an innovative neuropharmacological concept into therapeutics
    Luc Zimmer, Adrian Newman‐Tancredi · 2024 · Neuropharmacology
27. Identification of 1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Derivatives as a Novel δ Opioid Receptor-Selective Agonist Chemotype
    Yazan J. Meqbil, Jhoan Sebastian Aguilar, Arryn T. Blaine, Lan Chen, Robert J. Cassell, Amynah A. A. Pradhan, Richard M. van Rijn · 2024 · Journal of Pharmacology and Experimental Therapeutics
28. Design of allosteric modulators that change GPCR G protein subtype selectivity
    Madelyn N. Moore, Kelsey L. Person, Abigail R. Alwin, Campbell Krusemark, Noah Foster, Caroline Ray, Asuka Inoue, Michael R. Jackson, Michael J. Sheedlo, Larry S. Barak et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
29. Agonist-selective activation of individual G-proteins by muscarinic receptors
    Dominik Nelic, Nikolai Chetverikov, Martina Hochmalová, Christina Diaz, Vladimı́r Doležal, John Boulos, Ján Jakubík, Kirill A. Martemyanov, Alena Randáková · 2024 · Scientific Reports
30. N-terminally modified GLP1R agonists drive G protein bias via extracellular loop 3 displacement
    Lihua Zhao, Qian He, Qingning Yuan, Guan-Guan Zhao, Gaihong Wang, Hua-Ling Pan, H. Eric Xu · 2026 · Cell Reports
31. Post-translational modifications orchestrate the intrinsic signaling bias of GPR52
    Bingjie Zhang, Wei Ge, Mengna Ma, Shanshan Li, Jie Yu, Guang Yang, Huilan Wang, Jingwen Li, Qingrun Li, Rong Zeng et al. · 2025 · Nature Chemical Biology
32. Chemokine receptors – Exemplifying functional divergence in G protein-coupled receptors
    Omolade Otun, Sébastien Granier, Thierry Durroux, Chérine Bechara · 2025 · Molecular Pharmacology
33. Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach
    Péter Buchwald · 2023 · Frontiers in Pharmacology
34. Biased antagonism of a series of bicyclic CXCR2 intracellular allosteric modulators
    Brent Van Bosstraeten, Katrijn Boon, Max Van Hoof, Wim Dehaen, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Steven De Jonghe, Tom Van Loy · 2025 · Frontiers in Pharmacology
35. Identification of a regulatory sequence within the third intracellular loop that governs β-arrestin binding to the muscarinic M5 receptor
    Sophie A. M. Steinmüller, Keith Thompson, Judith Alenfelder, Julia Drube, Carsten Hoffmann, Evi Kostenis, Dawn Thompson, James N. Hislop · 2025 · Cellular Signalling
36. Discovery of Novel β-Arrestin Biased Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis
    Chang Yong Lee, Lizaveta Gotina, Jushin Kim, Jaehwan Kim, Jeeyun Ahn, Woo Seung Son, Seon Hee Seo, Jiwoo Park, Min-Sik Kang, Jaeick Lee et al. · 2025 · Journal of Medicinal Chemistry
37. Biased Agonists of the Type 1 Angiotensin II Receptor Promote Distinct Subcellular β-Arrestin Conformations
    Anand Chundi, Uyen Pham, Srikrishna Darbha, Sudarshan Rajagopal · 2025 · Biochemistry
38. OpioidBias: A Machine Learning Tool for Predicting the Biased Agonism of Opioid Ligands
    R Rajkumar., Anju Sharma, Anuradha Badade, Tanmaykumar Varma, Prabha Garg · 2025 · ACS Medicinal Chemistry Letters
39. Mit sichtbarem Licht schaltbare Benzimidazol‐Azo‐Arene wirken als β‐Arrestin2 funktionell selektive Cannabinoid‐Rezeptor 2 Agonisten
    Sophie A. M. Steinmüller, Julia Fender, Marie H. Deventer, Anna Tutov, Kristina Lorenz, Christophe Pol Stove, James N. Hislop, Michael W. Decker · 2023 · Angewandte Chemie
40. Molecular Glues: A New Approach to Modulating GPCR Signaling Bias
    Jamie Kushnir, Ryan H. Gumpper · 2025 · Biochemistry
41. A bio. tools collection of online resources for GPCR research
    Tõnis Laasfeld, Friederike Wunsch, Avgi E. Apostolakou, Adrián García‐Recio, Gáspár Pándy‐Szekeres, Sławomir Filipek, Masha Y. Niv, Jana Selent, David E.I. Gloriam, Marcel Bermúdez · 2025 · British Journal of Pharmacology
42. Where are we now? Biased signalling of Class B G protein-coupled receptor-targeted therapeutics
    Zoe Tasma, Michael L. Garelja, Aqfan Jamaluddin, Tyla I. Alexander, Tayla A. Rees · 2025 · Pharmacology & Therapeutics
43. Making the switch: The role of Gq in driving GRK selectivity at GPCRs
    Parishmita Sarma, Shirsha Saha, Arun K. Shukla · 2022 · Science Signaling
44. Current strategic trends in drug discovery: the present as prologue
    David R. Janero · 2023 · Expert Opinion on Drug Discovery
45. Biased activation of the vasopressin V2 receptor probed by NMR, paramagnetic ligands, and molecular dynamics simulations
    Gérald Gaibelet, Aurélien Fouillen, Stéphanie Riché, Hélène Orcel, Christiane Mendre, Ali Kanso, Romain Lanotte, Julie Nguyen, Juliette Dimon, Serge Urbach et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
46. An Online Biased Signaling Atlas
    Jimmy Caroli, Alibek Mamyrbekov, Kasper Harpsøe, Sahar Gardizi, Linda Dörries, Eshan Ghosh, Alexander S. Hauser, Albert J. Kooistra, David E.I. Gloriam · 2022 · Research Square
47. Deletion of arrestin-3 does not improve compulsive drug-seeking behavior in a longitudinal paradigm of oral morphine self-administration
    Sarah Warren Gooding, Lindsey C. Felth, Randi L. Foxall, Zachary Rosa, Kyle E. Ireton, Izabella Sall, Joshua Gipoor, Anirudh Gaur, Madeline King, Noah Dirks et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
48. Physiological bias governs neutrophil inflammatory threat perception
    Denise Pajonczyk, Lina Pauli, Charlotte Pünt, Merle F. Sternschulte, Olesja Fehler, Thomas Vogl, Oliver Soehnlein, Marcel Bermúdez, Carsten Alexander Raabe, Ursula Rescher · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
49. Resonating with the signaling bias of CXCR7
    Parishmita Sarma, Arun K. Shukla · 2022 · Molecular Cell
50. Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context
    Nathan Vanalken, Katrijn Boon, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy · 2024 · Biosensors
51. Rational Design of Drugs Targeting G-Protein-Coupled Receptors: Ligand Search and Screening
    Aleksandra P. Luginina, Andrey N Khnykin, Polina A. Khorn, Olga V. Moiseeva, Nadezhda A. Safronova, Vladimir A. Pospelov, Dmitrii E. Dashevskii, Anatoliy Belousov, Valentin I. Borschevskiy, Alexey Mishin · 2024 · Biochemistry (Moscow)
52. Biased Signaling in G Protein-Coupled Receptors: Understanding the Biological Relevance and Tools for Probing Functionally Selective Ligands
    Braden S. Fallon, Kathleen E. Rondem, Elizabeth J. Mumby, Justin G. English · 2025 · Biochemistry
53. Critical Residues in the Gβ Subunit Mediate Selective Recruitment of the Gαq Heterotrimer to Activated G Protein-Coupled Receptors
    Yunjin Yao, Dongxue Wang, Shiqi Wang, Xiaoyan Ouyang, Lan‐Xue Zhao, Hongzhuan Chen, Jianrong Xu · 2025 · ACS Pharmacology & Translational Science
54. G-protein coupled estrogen receptor 1 activation by daidzein and G-1 in triple negative breast cancer
    Yasmine Mostaphaoui, R. Menad, Claire Brun, Elara Moudilou · 2025 · Biochemical and Biophysical Research Communications
55. Molecular simulation-based 3D structural construction of olfactory receptor with agonist binding
    Takumi Hirao, Yusuke Ihara, Chiori Ijichi, Genki Kudo, Ryunosuke Yoshino, Takatsugu Hirokawa · 2025 · Journal of Computer-Aided Molecular Design
56. Live cell luminescence-based Gαq-PLC-β interaction assay: Development and application at the serotonin 5-HT2A receptor
    Eline Pottie, Christophe Pol Stove · 2026 · Pharmacological Research
57. β-Arrestins and disease-linked variants: opportunities for targeted modulation
    Simon Hasinger, Andreas Fraunhofer, Julius Hermes, Peter James McCormick, Christian W. Gruber · 2026 · Trends in Pharmacological Sciences
58. N -Benzyl-tryptamine Derivatives as Serotonin 5-HT 2A Receptor (5-HT 2A R) Agonists: Focus on Different In Vitro 5-HT 2A R Activity Profiles
    Eline Pottie, Emma Vertriest, Darío Martínez-Afani, Breno A. Soares, Bruce K. Cassels, Christophe Pol Stove · 2026 · ACS Chemical Neuroscience
59. Dynamic Pathway Selectivity of TAS2R5 toward or Away from β-Arrestin or G Protein from Biased Agonists
    Donghwa Kim, Hannah R. Strzelinski, Camille M. Longabardi, Stephen B. Liggett · 2026 · Biochemistry
60. Biosensors for translatable GPCR bias
    Renlei Ji, Ya‐Xiong Tao · 2026 · Trends in Pharmacological Sciences
61. Molecular mechanisms of naturally encoded signaling bias at the complement anaphylatoxin receptors
    Divyanshu Tiwari, Kazuhiro Sawada, Annu Dalal, Sudha Mishra, Xaria X. Li, Joshua C Dent, Kiae Kim, Manish Kumar Yadav, Nabarun Roy, Manisankar Ganguly et al. · 2026 · Molecular Cell
62. Quantitation of Phosphorylation Preferences of EGFR Tyrosines in Response to HB‐EGF and EGF
    Ece Özdemir, Mahmoud Abouelkheir, Kalina A. Hristova · 2026 · Chemistry - Methods
63. Why classical receptor theory, which ignores allostery, can effectively measure the strength of an allosteric effect as agonist's efficacy
    H. Ongun Onaran, Tommaso Costa · 2024 · British Journal of Pharmacology
64. GABAB Receptor Positive Allosteric Modulators: Novel Approaches for Drug Design and Discovery
    Linn Samira Mari Evenseth · 2024 · The Receptors
65. Research approaches for exploring the hidden conversations of G protein-coupled receptor transactivation
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66. Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System
    Yamina A. Berchiche, Terence E. Hébert · 2022 · Frontiers in Cellular Neuroscience
67. How can we improve the measurement of receptor signaling bias?
    Karim Nagi · 2023 · Expert Opinion on Drug Discovery
68. Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profiles
    Denise Pajonczyk, Merle F. Sternschulte, Oliver Soehnlein, Marcel Bermúdez, Carsten Alexander Raabe, Ursula Rescher · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
69. Visualizing the M2 muscarinic acetylcholine receptor activation regulated by aromatic ring dynamics
    Zhou Gong, Xu Zhang, Maili Liu, Changwen Jin, Yunfei Hu · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
70. Computational Analysis of Fully Activated Orexin Receptor 2 Across Various Thermodynamic Ensembles with Surface Tension Monitoring
    Rafael Doležal · 2024 · ChemRxiv
71. Molecular mechanism of naturally-encoded signaling-bias at the complement anaphylatoxin receptors
    Divyanshu Tiwari, Kazuhiro Sawada, Annu Dalal, Sudha Mishra, Xaria X. Li, Joshua C. Dent, Kiae Kim, Manish Kumar Yadav, Nabarun Roy, Manisankar Ganguly et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
72. Designing Rigid Protein Fiducials to Visualize GPCR Conformational States
    Alina Vo Vo, Yuan-En Sun, Justin G. English, Michael J. Robertson · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
73. Potency, dissociation kinetics and reversibility of fentanyls and nitazenes by naloxone at the μ opioid receptor
    Alhosan, Norah, Cavallo, Damiana, Santiago, Marina, Kelly, Eamonn, Henderson, Graeme · 2024
74. Computational and experimental approaches to probe GPCR activation and signaling
    Paulina Dragan, Alessandro Atzei, Swapnil Ganesh Sanmukh, Dorota Latek · 2022 · Progress in molecular biology and translational science
75. Why classical receptor theory, which ignores allostery, can effectively measure the strength of an allosteric effect underlying the ligand efficacy
    H. Ongun Onaran, Tommaso Costa · 2023
76. Author Response: Ligand bias underlies differential signaling of multiple FGFs via FGFR1
    Kelly Karl, Nuala Del Piccolo, Taylor P. Light, Tanaya Roy, Pooja Dudeja, Vlad-Constantin Ursachi, Bohumil Fafílek, Pavel Krejčı́, Kalina A. Hristova · 2023 · eLife
77. Joint Public Review: Ligand bias underlies differential signaling of multiple FGFs via FGFR1
    2023 · eLife
78. eLife Assessment: Ligand bias underlies differential signaling of multiple FGFs via FGFR1
    Volker Dötsch · 2023 · eLife
79. No Evidence for Endocannabinoid-Induced G Protein Subtype Selectivity at Human and Rodent Cannabinoid CB 1 Receptors
    Xiaoxi Zheng, Beth Ehrlich, David Finlay, Michelle Glass · 2024 · Cannabis and Cannabinoid Research
80. Weekly inhaled salmeterol xinafoate, a selective β2 adrenergic receptor agonist drug, therapeutically inhibits cancer growth and prolongs survival in vivo
    Xiaofei She, Junxian Ma, Hua Gao · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
81. Post-translational modifications orchestrate the intrinsic signaling bias of orphan receptor GPR52
    Bingjie Zhang, Mengna Ma, Wei Ge, Shanshan Li, Guang Yang, Huilan Wang, Boxun Lu, Wenqing Shui · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
82. Rational drug design targeting G-protein-coupled receptors: ligand search and screening (review)
    Aleksandra P. Luginina, Andrey N Khnykin, Polina A. Khorn, Olga V. Moiseeva, Nadezhda A. Safronova, В. А. Поспелов, Dmitrii E. Dashevskii, A. S. Belousov, I. V. Borshchevskiy, Alexey Mishin · 2024 · Biochemistry (Moscow)
83. Downstream Signaling of Muscarinic M4 Receptors Is Regulated by Receptor Density and Cellular Environment
    Madeleine Merz, Charlotte Playle, Monika R. Palchaudhuri, Oliver Hucke, Ulrike Gross, Daniel Ursu · 2025 · Pharmacology Research & Perspectives
84. THE ACTIN CYTOSKELETON CONTROLS NADPH OXIDASE ACTIVATION AND G PROTEIN RECRUITMENT MEDIATED BY NEUTROPHIL Gαq-COUPLED RECEPTORS
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85. Disruption of the actin cytoskeleton with latrunculin A controls ATP-induced NADPH oxidase activity and the recruitment of G proteins by neutrophil Gαq-coupled receptors
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86. Dopamine receptor drugs and their applications
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87. New modalities: Drugging the undruggable GPCR targets
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88. Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo
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89. Biased Agonism at β-Adrenoceptor Subtypes: A Drug Development Perspective
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90. To Be Biased or Not to Be: A Play for G-Protein Coupled Receptors
    Nikitas G. Liolitsas, Evangelia Pantazaka, Εvangelia Papadimitriou · 2025 · International Journal of Translational Medicine
91. Investigation into ligand selectivity and bias at the formyl peptide receptor family
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92. Additional file 1 of Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over β-arrestin recruitment and receptor internalization
    Katrijn Boon, Nathan Vanalken, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy · 2024 · Figshare
93. Hyaline: Geometric Deep Learning for Accurate Prediction of G Protein-Coupled Receptor Activation States from Structure
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94. Information Transmission and Processing Ing-Protein-Coupled-Receptor Complexes
    Roger D. Jones, Achille Giacometti, Alan M. Jones · 2025 · SSRN Electronic Journal
95. Editorial commentary on Special issue: Ligand bias
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96. Research Progress on Biased Signaling of G Protein-Coupled Receptors and Their Downstream Pathway Network Interactions in the Skin and Immune System
    裕添 马 · 2026 · Pharmacy Information
97. G protein-coupled receptor pharmacology: Tools, techniques and assays for drug discovery
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98. Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits
    Davide Malfacini, Riccardo Camilotto, M. Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calò · 2026 · British Journal of Pharmacology
99. Design and Synthesis of Dualsteric Muscarinic M5 Receptor Ligands Reveal G Protein Bias
    Sophie A. M. Steinmüller, Alix Flake, Marcel Bermúdez, Peter T. Ashdown, James N. Hislop, Michael W. Decker · 2026 · ACS Chemical Neuroscience
100. Apelin-13 enhances the neural differentiation of dental pulp stem cells through the Wnt/β-catenin signaling pathway
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