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Cited by 44Contact Dermatitis and AllergiesOccupational exposure and asthmaDrug-Induced Adverse Reactions

The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.

Allergic contact dermatitis caused by 2‐hydroxyethyl methacrylate and ethyl cyanoacrylate contained in cosmetic glues among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications: A systematic review

Open access
Symanzik, Cara, Weinert, Patricia, Babić, Željka, Hallmann, Sarah, Havmose, Martin S., Johansen, Jeanne D., Kezic, Sanja, Macan, Marija, Macan, Jelena, Strahwald, Julia, Turk, Rajka, van der Molen, Henk F., John, Swen M., Uter, Wolfgang·2022·Contact Dermatitis
DOI 10.1111/cod.14056
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Abstract

Current cosmetic regulations primarily focus on protecting consumers, not the professional user who is subjected to a partly different, and certainly more intense exposure to hazardous substances. Against this background, this systematic review aims to compile and appraise evidence regarding skin toxicity of 2-hydroxyethyl methacrylate (HEMA; CAS no. 212-782-2) and ethyl cyanoacrylate (ECA; CAS no. 7085-85-0) contained in cosmetic glues used among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications. This systematic review followed the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) 2020 recommendations for reporting systematic reviews and meta-analysis. In total, six publications from six countries were eligible for this systematic review. A meta-analysis revealed that hairdressers and beauticians have a ninefold increased risk of developing contact allergy to HEMA compared with controls who are not hairdressers and beauticians. Results for ECA are lacking. The results of this systematic review clearly show that-regarding contact allergy to acrylates-it is not appropriate to apply risk assessment for consumers to hairdressers and beauticians who occupationally handle cosmetic glues. The regulations in existence do not adequately address occupational risks for hairdressers and beauticians connected with the use of acrylate-containing cosmetic substances and need reconsideration.

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Registry

Crossref · 10.1111/cod.14056

Cites

74 of 74 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

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  • In a study of 82 cosmetic product categories, 47 products contained 1,4-dioxane with an average amount of 1.54 μg/g in children's skincare products.

    “As a result, 47 of the 82 products contained 1,4-dioxane with an average amount of 1.54 micrograms/gram (μg/g) in children’s skincare products (42).”

    From The dark side of beauty: an in-depth analysis of the health hazards and toxicological impact of synthetic cosmetics and personal care products (2024) · cites this paper as [42]

    The Introduction (p. 2) discusses occupational exposure to cosmetic ingredients, and the Discussion (p. 10) addresses acrylates in cosmetic glues. Searches for 1,4-dioxane, 47 of 82 products, and 1.54 μg/g found no passage reporting the claimed result for children’s skincare products. (LLM, conf=0.76)

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Research works printed but not linked: 2

  1. Kieć‐Swierczyńska M, 2010, Wet work, Med Pr, 61, 65
  2. 10.1097/01634989-199703000-00018 · DOI

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Metadata

Authors
Symanzik, C., Weinert, P., Babić, Ž., Hallmann, S., Havmose, M. S., Johansen, J. D., Kezic, S., Macan, M., Macan, J., Strahwald, J., Turk, R., van der Molen, H. F., John, S. M., & Uter, W.
Affiliations
  • Osnabrück University (DE)
  • Institute for Medical Research and Occupational Health (HR)
  • Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
  • University of Copenhagen (DK)
  • Amsterdam UMC, University of Amsterdam, Department of Public and Occupational Health Amsterdam Public Health Research Institute Amsterdam The Netherlands
Corresponding author
Symanzik, Cara
ORCID
Venue
Contact Dermatitis
Publisher
Wiley
Published
2022-02-15
Volume
86
Issue
6
Pages
480-492
ISSN
  • 0105-1873 (ISSN-L)
  • 1600-0536
DOI
10.1111/cod.14056
OpenAlex
W4210783713
Cited by
44
References
74
Citations by year
2026: 4 · 2025: 7 · 2024: 15 · 2023: 13 · 2022: 5
FWCI
1.78
Type
journal article
Language
en
Open access
Licence
Locations
  • Contact Dermatitis (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
  • Pure Amsterdam UMC (submittedVersion, other-oa)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • OPUS FAU (Kooperativer Bibliotheksverbund Berlin-Brandenburg (KOBV), on behalf of the Universitätsbibliothek Erlangen-Nürnberg) (submittedVersion, cc-by)
Funders
European Commission
Topics
  • Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
  • Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
Keywords
allergic contact dermatitis, 2-hydroxyethyl methacrylate, ethyl cyanoacrylate, hairdressers, beauticians, nail treatment, eyelash extensions, occupational exposure, acrylates, cosmetic regulation, risk assessment
MeSH terms
Cosmetics, Cyanoacrylates, Hair, Humans, Methacrylates, Dermatitis, Occupational, Dermatitis, Allergic Contact

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