Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 28Sports Performance and TrainingCardiovascular and exercise physiologySmoking Behavior and Cessation

The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

Nicotine effects on exercise performance and physiological responses in nicotine‐naïve individuals: a systematic review

Johnston, Robert, Doma, Kenji, Crowe, Melissa·2018·Clinical Physiology and Functional Imaging
DOI 10.1111/cpf.12443
Open this paper in CoChat — free account

Abstract

Summary: The purpose of this systematic review was to evaluate the effects of smokeless forms of nicotine on physiological responses and exercise performance. Methodology and reporting were based on the PRISMA statement. The intervention was defined as any product containing nicotine that did not require smoking. Searches were conducted across two electronic databases with supplementary approaches utilized. Studies were selected following set inclusion and exclusion criteria and checked by two independent authors. A modified PED ro scale was utilized to rate study quality with studies averaging 9·3/13. Six studies assessed exercise performance with endurance‐based parameters reported as significantly improved with nicotine in one study, while anaerobic parameters were unaffected or decreased compared to placebo except in one study which reported enhanced leg extensor torque but no effect on countermovement jump or Wingate anaerobic capacity. Sixteen of 28 studies investigating physiological responses reported that nicotine significantly increased heart rate compared to placebo or control. Blood pressure and blood flow were also reported as significantly increased in multiple studies. While there is strong evidence of nicotine‐induced changes in physiological function that would benefit physical performance, beneficial effects have only been reported on leg extensor torque and endurance performance by one study each. Subsequently, there is need for more research with strong methodological quality to definitively evaluate nicotine's potential as an ergogenic aid.

Overview

Integrity signals

Registry

Crossref · 10.1111/cpf.12443

Cites

70 of 70 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Citations

Cites

Show all 70 references

Cited by

Related

See all

Metadata

Authors
Johnston, R., Doma, K., & Crowe, M.
Affiliations
James Cook University (AU)
Corresponding author
Doma, Kenji
ORCID
Venue
Clinical Physiology and Functional Imaging
Publisher
Wiley
Published
2017-06-02
Volume
38
Issue
4
Pages
527-538
ISSN
  • 1475-0961 (ISSN-L)
  • 1475-097X
DOI
10.1111/cpf.12443
OpenAlex
W2620652337
Semantic Scholar
a488aaccc974733e982225837c36e0b1fecfac9f
Cited by
28
References
70
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 3 · 2017: 1
FWCI
0.72
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Clinical Physiology and Functional Imaging (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords
nicotine, exercise performance, endurance performance, anaerobic performance, heart rate, blood pressure, blood flow, countermovement jump, Wingate test, ergogenic aids
MeSH terms
Adult, Biomechanical Phenomena, Female, Hemodynamics, Humans, Male, Muscle Contraction, Nicotine, Physical Endurance, Exercise, Muscle, Skeletal, Nicotinic Agonists, Torque, Young Adult, Performance-Enhancing Substances

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.