The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
PAS and GMS utility in dermatopathology: Review of the current medical literature
Open accessAbstract
The American Society of Dermatopathology has established an Appropriate Use Criteria (AUC) Committee with the intention of establishing evidence-based recommendations regarding the appropriateness of various ancillary tests commonly utilized by dermatopathologists. Periodic acid Schiff (PAS) and Grocott (or Gomori) methenamine silver (GMS) stains represent some of the most commonly employed ancillary tests in dermatopathology. The utility of these tests was targeted for evaluation by the AUC. This literature review represents a comprehensive evaluation of available evidence for the utility of PAS and/or GMS staining of skin and nail biopsies. In concert with expert opinion, these data will be incorporated into future recommendations by the AUC for PAS and GMS staining in routine dermatopathology practice.
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“These cases usually require careful histological examination and the use of special stains, such as periodic acid–Schiff (PAS) and Gomori methenamine silver (GMS) [24,25,26].”
From Artificial Intelligence in the Histopathological Assessment of Non-Neoplastic Skin Disorders: A Narrative Review with Future Perspectives (2025) · cites this paper as [25]
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Cites
Comparison of diagnostic methods in the evaluation of onychomycosis
Weinberg, J. M., Koestenblatt, E. K., Tutrone, W. D., et al. (2003) · Journal of the American Academy of Dermatology · doi:10.1067/s0190-9622(03)01480-4 · Cited by 297
Methods for Diagnosing Onychomycosis
Lawry, M. A., Haneke, E., Strobeck, K., Martin, S., Zimmer, B. A., & Romano, P. S. (2000) · Archives of Dermatology · doi:10.1001/archderm.136.9.1112 · Cited by 175
Histologic Evaluation of Nail Clippings for Diagnosing Onychomycosis
Suarez, S. M. (1991) · Archives of Dermatology · doi:10.1001/archderm.1991.01680090081008 · Cited by 107
Shenoy, M., Teerthanath, S., Karnaker, V. K., et al. (2008) · Indian Journal of Dermatology Venereology and Leprology · doi:10.4103/0378-6323.39584 · Cited by 104
Lilly, K. K., Koshnick, R. L., Grill, J. P., Khalil, Z. M., Nelson, D. B., & Warshaw, E. M. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2006.03.033 · Cited by 92
Histopathological diagnosis of onychomycosis by periodic acid-Schiff-stained nail clippings
Reisberger, E.-M., Abels, C., Landthaler, M., et al. (2003) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2003.05029.x · Cited by 89
New reasons for histopathological nail‐clipping examination in the diagnosis of onychomycosis
Wilsmann‐Theis, D., Sareika, F., Bieber, T. R. M., et al. (2010) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2010.03704.x · Cited by 88
Usefulness of Histological Examination for the Diagnosis of Onychomycosis
Gianni, C., Morelli, V., Cerri, A., Greco, C., Rossini, P., Guiducci, A., Braidotti, P., Calcaterra, R., & Papini, M. (2001) · Dermatology · doi:10.1159/000051659 · Cited by 74
Comparison of diagnostic methods for onychomycosis, and proposal of a diagnostic algorithm
Jung, M. Y., Shim, J., Lee, J. H., et al. (2015) · Clinical and Experimental Dermatology · doi:10.1111/ced.12593 · Cited by 66
Comparison of direct smear, culture and histology for the diagnosis of onychomycosis
Karimzadegannia, M., Mohammadi, A. M., Bouzari, N., & Firooz, A. (2007) · Australasian Journal of Dermatology · doi:10.1111/j.1440-0960.2007.00320.x · Cited by 66
Research works printed but not linked: 2
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- Mehregan DA, 1997, Onychomycosis, Cutis, 59, 247
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Della Mura, M., Sorino, J., Colagrande, A., Daruish, M., Ingravallo, G., Massaro, A., Cazzato, G., Lupo, C., Casatta, N., Ribatti, D., et al. (2025) · Medical Sciences · doi:10.3390/medsci13020070 · Cited by 6
Metadata
- Authors
- Shalin, S. C., Ferringer, T., & Cassarino, D. S.
- Affiliations
- University of Arkansas for Medical Sciences (US)
- Geisinger Medical Center (US)
- Kaiser Permanente (US)
- Corresponding author
- Cassarino, David S.
- Venue
- Journal of Cutaneous Pathology
- Publisher
- Wiley
- Published
- 2020-08-22
- Volume
- 47
- Issue
- 11
- Pages
- 1096-1102
- ISSN
- 0303-6987 (ISSN-L)
- 1600-0560
- OpenAlex
- W3033941366
- Cited by
- 36
- References
- 53
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 9 · 2023: 7 · 2022: 6 · 2021: 3
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Cutaneous Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Nail Diseases and Treatments
- Health Sciences › Medicine › Dermatology › Medicine and Dermatology Studies History
- Health Sciences › Medicine › Dermatology › Cancer and Skin Lesions
- Keywords
- PAS staining, Gomori methenamine silver staining, appropriate use criteria, ancillary testing, dermatopathology, nail biopsy, skin biopsy, evidence-based recommendations
- MeSH terms
- Dermatology, Humans, Methenamine, Pathology, Periodic Acid-Schiff Reaction, Skin Diseases, Staining and Labeling
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- CoChat. (2026). Citation check: PAS and GMS utility in dermatopathology: Review of the current medical literature. https://app.cochat.ai/papers/10.1111/cup.13769
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- Shalin, S. C., Ferringer, T., & Cassarino, D. S. (2020). PAS and GMS utility in dermatopathology: Review of the current medical literature. Journal of Cutaneous Pathology. https://doi.org/10.1111/cup.13769
