A randomized controlled trial of web-based training to increase activity in children with cerebral palsy
Open accessAbstract
AIM: To determine the efficacy of web-based training on activity capacity and performance in children with unilateral cerebral palsy (CP). METHOD: In a matched-pairs randomized waitlist controlled trial, independently ambulant children and adolescents with unilateral CP were allocated to receive 30 minutes of training (intervention) 6 days per week, or usual care (waitlist control) for 20 weeks. Activity capacity was assessed using maximal repetitions of functional strength tasks and 6-minute walk test (6MWT); performance using 4-day ActiGraph GT3X+ accelerometer records at baseline and 20 weeks. Data were analysed by intention to treat comparing between groups using hierarchical linear modelling. RESULTS: Participants were n=101, 52 males, mean age 11 years 3 months (SD 2y 4mo). Intervention participants completed a mean 32.4 hours (SD 17.2) of training, associated with significant improvements in functional strength (mean difference 19.3 repetitions; 95% confidence interval [CI] 10.8-27.7; p<0.001) and 6MWT distance (mean difference 38.9m; 95% CI 12.3-51.9; p<0.001) compared with the control group at 20 weeks, although not activity performance (p>0.05). INTERPRETATION: Training was effective at increasing functional strength and walking endurance in independently ambulant children with unilateral CP. This did not translate into improvements in activity performance.
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Nineteen studies reported in twenty randomized controlled trials, published between 2002 and 2016, were included in the review.
“Therefore, a total of 19 studies (in 20 RCTs) that were published between 2002 and 2016 were included in this review.41-44,46-61”
From Effectiveness of Virtual Reality in Children With Cerebral Palsy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (2018) · cites this paper as [44]
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- Web-Based Training for Children with Cerebral Palsy Louise E Mitchell et al. 773 14698749, 2016, 7, Downloaded from https://onlinelibrary.wiley.com/doi/10.1111/dmcn.13065, Wiley Online Library on [17/08/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
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- Authors
- Mitchell, L. E., Ziviani, J., & Boyd, R. N.
- Affiliations
- The University of Queensland (AU)
- Corresponding author
- Mitchell, Louise E
- Venue
- Developmental Medicine & Child Neurology
- Publisher
- Wiley
- Published
- 2016-02-15
- Volume
- 58
- Issue
- 7
- Pages
- 767-773
- ISSN
- 0012-1622 (ISSN-L)
- 1469-8749
- OpenAlex
- W2285687255
- Cited by
- 65
- References
- 24
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 5 · 2023: 6 · 2022: 10 · 2021: 6 · 2020: 10 · 2019: 6 · 2017: 6 · 2016: 2
- FWCI
- 4.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Developmental Medicine & Child Neurology (publishedVersion)
- PubMed (publishedVersion)
- eSpace (Curtin University) (submittedVersion)
- Funders
- Financial Markets Foundation for Children
- National Health and Medical Research Council (1037220)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Cerebral Palsy and Movement Disorders
- Social Sciences › Psychology › Developmental and Educational Psychology › Children's Physical and Motor Development
- Health Sciences › Medicine › Neurology › Botulinum Toxin and Related Neurological Disorders
- Keywords
- cerebral palsy, spastic hemiplegia, online training, online exercise intervention, children, adolescents, activity capacity, functional strength, walking endurance, 6-minute walk test, physical activity, ambulation
- MeSH terms
- Adolescent, Cerebral Palsy, Child, Exercise Therapy, Female, Humans, Functional Laterality, Longitudinal Studies, Male, Motor Activity, Netherlands, Online Systems, Surveys and Questionnaires, Case-Control Studies, Treatment Outcome, Statistics, Nonparametric, Accelerometry
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