Improving quality of care in people with Type 2 diabetes through the Associazione Medici Diabetologi‐annals initiative: a long‐term cost‐effectiveness analysis
Abstract
Aims The Associazione Medici Diabetologi-annals initiative is a physician-led quality-of-care improvement scheme that has been shown to improve HbA1c concentration, blood pressure, lipid profiles and BMI in enrolled people with Type 2 diabetes. The present analysis investigated the long-term cost-effectiveness of enrolling people with Type 2 diabetes in the Associazione Medici Diabetologi-annals initiative compared with conventional management. Methods Long-term projections of clinical outcomes and direct costs (in 2010 Euros) were made using a published and validated model of Type 2 diabetes in people with Type 2 diabetes who were either enrolled in the Associazione Medici Diabetologi-annals initiative or who were receiving conventional management. Treatment effects were based on mean changes from baseline seen at 5 years after enrolment in the scheme. Costs and clinical outcomes were discounted at 3% per annum. Results The Associazione Medici Diabetologi-annals initiative was associated with improvements in mean discounted life expectancy and quality-adjusted life expectancy of 0.55 years (95% CI 0.54-0.57) years and 0.48 quality-adjusted life years (95% CI 0.46-0.49), respectively, compared with conventional management. Whilst treatment costs were higher in the Associazione Medici Diabetologi-annals arm, this was offset by savings as a result of the reduced incidence and treatment of diabetes-related complications. The Associazione Medici Diabetologi-annals initiative was…
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In Italy, the Associazione Medici Diabetologi-annals initiative is a cost-saving method of improving clinical outcomes in type 2 diabetes mellitus patients because it improves HbA1c, blood pressure, lipid profiles, and BMI compared to conventional management methods.
“In Italy, the long-term projections of the Associazione Medici Diabetologi-annals initiative (a physician-led quality-of-care improvement program for T2DM patients) indicate that this initiative is a cost-saving method of improving clinical outcomes in T2DM patients because it improves HbA1c, blood pressure, lipid profiles, and BMI in enrolled patients compared to conventional management methods [”
From Clinical Inertia in the Management of Type 2 Diabetes Mellitus: A Systematic Review (2023) · cites this paper as [47]
Cites
Nathan, D. M., Buse, J. B., Davidson, M. B., Heine, R. J., Holman, R. R., Sherwin, R., & Zinman, B. (2006) · Diabetes Care · doi:10.2337/dc06-9912 · Cited by 1,195 · see citing works
Global healthcare expenditure on diabetes for 2010 and 2030
Zhang, P., Zhang, X., Brown, J., Vistisen, D., Sicree, R., Shaw, J., & Nichols, G. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2010.01.026 · Cited by 1,145 · see citing works
A Diabetes Report Card for the United States: Quality of Care in the 1990s
Saaddine, J., Engelgau, M., Beckles, G., Gregg, E., Thompson, T., & Narayan, K. M. V. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-8-200204160-00005 · Cited by 638 · see citing works
Palmer, A. J., Roze, S., Valentine, W. J., Minshall, M. E., FOOS, V., Lurati, F. M., Lammert, M., & Spinas, G. A. (2004) · Current Medical Research and Opinion · doi:10.1185/030079904x1980 · Cited by 523 · see citing works
Self-citationPrompers, L., Huijberts, M. S., Schaper, N. C., Apelqvist, J., Bakker, K., Edmonds, M. E., Holstein, P., Jude, E. B., Jirkovská, A., Mauricio, D., et al. (2008) · Diabetologia · doi:10.1007/s00125-008-1089-6 · Cited by 305 · see citing works
Validation of the CORE Diabetes Model Against Epidemiological and Clinical Studies
Palmer, A. J., Rozea, S., Valentinea, W. J., Minshallb, M. E., Foosa, V., Luratia, F. M., Lammerta, M., & Spinasc, G. A. (2004) · Current Medical Research and Opinion · doi:10.1185/030079904x2006 · Cited by 283 · see citing works
Solini, A., Penno, G., Bonora, E., Fondelli, C., Orsi, E., Arosio, M., Trevisan, R., Vedovato, M., Cignarelli, M., Andreozzi, F., et al. (2011) · Diabetes Care · doi:10.2337/dc11-1380 · Cited by 144 · see citing works
Self-citationThe Members of the Italian Group for Pharmacoeconomic Studies, Capri, S., Ceci, A., Terranova, L., Merlo, D. F., & Mantovani, L. G. (2001) · Drug Information Journal · doi:10.1177/009286150103500122 · Cited by 125 · see citing works
Acute coronary syndromes in Europe: 1-year costs and outcomes
Taylor, M. J., Scuffham, P., McCollam, P. L., & Newby, D. E. (2007) · Current Medical Research and Opinion · doi:10.1185/030079906x167462 · Cited by 87 · see citing works
The Comparative Medical Costs of Atherothrombotic Disease in European Countries
Lévy, É., Gabriel, S., & Dinet, J. (2003) · PharmacoEconomics · doi:10.2165/00019053-200321090-00003 · Cited by 84 · see citing works
Rossi, M. C., Nicolucci, A., Arcangeli, A., Cimino, A., Bigontina, G. D., Giorda, C. B., Meloncelli, I., Pellegrini, F., Valentini, U., Vespasiani, G., et al. (2008) · Diabetes Care · doi:10.2337/dc08-0469 · Cited by 81 · see citing works
Self-citationRossi, M. C., Lucisano, G., Comaschi, M., Coscelli, C., Cucinotta, D., Blasi, P. D., Bader, G., Pellegrini, F., Valentini, U., Vespasiani, G., et al. (2011) · Diabetes Care · doi:10.2337/dc10-1709 · Cited by 69 · see citing works
Self-citationNicolucci, A., Rossi, M. C., Arcangeli, A., Cimino, A., Bigontina, G. D., Fava, D., Gentile, S., Giorda, C. B., Meloncelli, I., Pellegrini, F., et al. (2010) · Diabetic Medicine · doi:10.1111/j.1464-5491.2010.03055.x · Cited by 65 · see citing works
Self-citationOptimization of insulin therapy in patients with Type 2 diabetes mellitus: beyond basal insulin
Blak, B. T., Smith, H. T., Hards, M., Curtis, B., & Iványi, T. (2012) · Diabetic Medicine · doi:10.1111/j.1464-5491.2012.03586.x · Cited by 50 · see citing works
The Direct Economic Cost of Pharmacologically-Treated Diabetes in Italy-2006. The ARNO Observatory
Marchesini, G., Forlani, G., Rossi, E., Berti, A., & Rosa, M. D. (2010) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2009.10.009 · Cited by 45 · see citing works
Sicili@, C. D. (2007) · Diabetes Care · doi:10.2337/dc07-1515 · Cited by 34 · see citing works
Pugliese, G., Solini, A., Zoppini, G., Fondelli, C., Zerbini, G., Vedovato, M., Cavalot, F. L., Lamacchia, O., Buzzetti, R., Morano, S., et al. (2012) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.09.006 · Cited by 29 · see citing works
Self-citationAmbrosetti, M., Salerno, M., Boni, S. N. D., Daniele, G., Tramarin, R., & Pedretti, R. F. E. (2004) · PubMed · Cited by 13 · see citing works
[AMD Annals: a model of continuous monitoring and improvement of the quality of diabetes care].
Saracci, R., Terracini, B., & Merletti, F. (2011) · PubMed · Cited by 11 · see citing works
PRM58 Long-Term Validation of the IMS CORE Diabetes Model in Type 1 and Type 2 Diabetes
FOOS, V., Palmer, J. L., Grant, D., Lloyd, A., Lamotte, M., & McEwan, P. (2012) · Value in Health · doi:10.1016/j.jval.2012.08.1521 · Cited by 10 · see citing works
Capri, S., & Perlini, S. (2005) · Current Medical Research and Opinion · doi:10.1185/030079905x46331 · Cited by 9 · see citing works
Palmer, A. J., Annemans, L., Roze, S., Lamotte, M., Berto, P., Ravera, M., & Rodby, R. A. (2005) · PharmacoEconomics Italian Research Articles · doi:10.1007/bf03320534 · Cited by 3 · see citing works
Analisi dei costi sanitari per lo scompenso cardiaco nella regione Marche
Politi, C., Deales, A., Cicchitelli, F., Marcobelli, A., Barbadoro, P., Zorzan, R., & Stanislao, F. D. (2005) · PharmacoEconomics Italian Research Articles · doi:10.1007/bf03320547 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Central nervous pathways of insulin action in the control of metabolism and food intake
Kullmann, S., Kleinridders, A., Small, D. M., Fritsche, A., Häring, H.-U., Preissl, H., & Heni, M. (2020) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(20)30113-3 · Cited by 233 · see citing works
Cost-effectiveness of Interventions to Manage Diabetes: Has the Evidence Changed Since 2008?
Siegel, K. R., Ali, M. K., Zhou, X., Ng, B. P., Jawanda, S., Proia, K. K., Zhang, X., Gregg, E. W., Albright, A. L., & Zhang, P. (2020) · Diabetes Care · doi:10.2337/dci20-0017 · Cited by 168 · see citing works
Clinical Inertia in the Management of Type 2 Diabetes Mellitus: A Systematic Review
Almigbal, T. H., Alzarah, S. A., Aljanoubi, F. A., Alhafez, N. A., Aldawsari, M. R., Alghadeer, Z. Y., & Alrasheed, A. A. (2023) · Medicina · doi:10.3390/medicina59010182 · Cited by 58 · see citing works
“In Italy, the long-term projections of the Associazione Medici Diabetologi-annals initiative (a physician-led qualityof-care improvement program for T2DM patients) indicate that this initiative is a cost-saving method of improving clinical outcomes in T2DM patients because it improves HbA1c, blood pressure, lipid prof…”
BackgroundRossi, M. C., Candido, R., Ceriello, A., Cimino, A., Bartolo, P. D., Giorda, C. B., Esposito, K., Lucisano, G., Maggini, M., Mannucci, E., et al. (2014) · Acta Diabetologica · doi:10.1007/s00592-014-0688-6 · Cited by 53 · see citing works
Self-citationRossi, M. C., Lucisano, G., Funnell, M. M., Pintaudi, B., Bulotta, A., Gentile, S., Scardapane, M., Skovlund, S. E., Vespasiani, G., & Nicolucci, A. (2015) · Patient Education and Counseling · doi:10.1016/j.pec.2015.05.012 · Cited by 50 · see citing works
Self-citationManicardi, V., Russo, G. T., Napoli, A., Torlone, E., Volsi, P. L., Giorda, C. B., Musacchio, N., Nicolucci, A., SURACI, C., Lucisano, G., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162960 · Cited by 49 · see citing works
Self-citationMusacchio, N., Giancaterini, A., Guaita, G., Ozzello, A., Pellegrini, M. A., Ponzani, P., Russo, G. T., Zilich, R., & Micheli, A. D. (2020) · Journal of Medical Internet Research · doi:10.2196/16922 · Cited by 44 · see citing works
The AMD ANNALS: A continuous initiative for the improvement of type 2 diabetes care
Russo, G., Di Bartolo, P., Candido, R., Lucisano, G., Manicardi, V., Giandalia, A., Nicolucci, A., Rocca, A., Rossi, M. C., & Di Cianni, G. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110672 · Cited by 39 · see citing works
Self-citationNuckols, T. K., Keeler, E. B., Anderson, L., Green, J., Morton, S. C., Doyle, B. J., Shetty, K. D., Arifkhanova, A., Booth, M. S., Shanman, R., et al. (2018) · Diabetes Care · doi:10.2337/dc17-1495 · Cited by 39 · see citing works
The complex interplay between clinical and person-centered diabetes outcomes in the two genders
on behalf of the BENCH-D Study Group, Rossi, M. C., Lucisano, G., Pintaudi, B., Bulotta, A., Gentile, S., Scardapane, M., Skovlund, S. E., Vespasiani, G., & Nicolucci, A. (2017) · Health and Quality of Life Outcomes · doi:10.1186/s12955-017-0613-0 · Cited by 28 · see citing works
Self-citationHua, X., Lung, T. W.-C., Palmer, A. J., Si, L., Herman, W. H., & Clarke, P. (2016) · PharmacoEconomics · doi:10.1007/s40273-016-0466-0 · Cited by 19 · see citing works
Barker, L. C., Kurdyak, P. A., Jacob, B. J., & Vigod, S. N. (2017) · Journal of Women s Health · doi:10.1089/jwh.2017.6490 · Cited by 7 · see citing works
Giorda, C. B., Rossi, A., Baccetti, F., Zilich, R., Romeo, F., Nreu, B., Cianni, G. D., Guaita, G., Morviducci, L., Muselli, M., et al. (2023) · Clinical Therapeutics · doi:10.1016/j.clinthera.2023.06.006 · Cited by 6 · see citing works
Self-citationRavasio, R., & Grassi, G. (2018) · Global & Regional Health Technology Assessment · doi:10.1177/2284240318773201 · Cited by 4 · see citing works
Guarino, G., Strollo, F., Corte, T. D., Satta, E., Romano, C., Alfarone, C., Corigliano, G., Corigliano, M., Cozzolino, G., Brancario, C., et al. (2022) · Diabetology · doi:10.3390/diabetology3020022 · Cited by 3 · see citing works
Fusco, A., Colarusso, S., Piscopo, M., Improta, M. R., Corigliano, M., Martedì, E., Oliva, D., Santorelli, A., Simonetti, R. G., Giammarco, A., et al. (2017) · Heart Research - Open Journal · doi:10.17140/hroj-4-141
El desafío de la diabetes en Chile
de Salud, C. M. (2016)
- Authors
- Giorda, C. B., Nicolucci, A., Pellegrini, F., Kristiansen, C. K., Hunt, B., Valentine, W. J., & Vespasiani, G.
- Affiliations
- ASL TO5 Chieri Turin Italy
- Mario Negri Sud Foundation (IT)
- Novo Nordisk (Denmark) (DK)
- Ossian Health Economics and Communications Basel Switzerland
- Madonna del Soccorso Hospital San Benedetto del Tronto Italy
- Corresponding author
- Kristiansen, C. K.
- Venue
- Diabetic Medicine
- Publisher
- Wiley
- Published
- 2013-12-24
- Volume
- 31
- Issue
- 5
- Pages
- 615-623
- ISSN
- 0742-3071 (ISSN-L)
- 1464-5491
- OpenAlex
- W2015147331
- Cited by
- 17
- References
- 23
- Citations by year
- 2023: 3 · 2022: 1 · 2020: 3 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 1
- FWCI
- 3.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Novo Nordisk
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 2 diabetes, healthcare quality improvement, cost-effectiveness, quality-adjusted life years, life expectancy, diabetes complications, HbA1c, Italy
- MeSH terms
- Aged, Cost-Benefit Analysis, Diabetes Mellitus, Type 2, Female, Humans, Italy, Male, Middle Aged, Quality of Health Care, Time Factors, Incidence, Health Care Costs, Outcome Assessment, Health Care, Quality-Adjusted Life Years, Disease Management, Diabetes Complications
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