The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Changing patterns in the epidemiology of β‐thalassemia
Open accessAbstract
β‐thalassemia major is an inherited hemoglobinopathy that requires lifelong red blood cell transfusions and iron chelation therapy to prevent complications due to iron overload. Traditionally, β‐thalassemia has been more common in certain regions of the world such as the Mediterranean, Middle East, and Southeast Asia. However, the prevalence of β‐thalassemia is increasing in other regions, including Northern Europe and North America, primarily due to migration. This review summarizes the available data on the changing incidence and prevalence of β‐thalassemia as well as factors influencing disease frequency. The data suggest that the epidemiology of β‐thalassemia is changing: Migration has increased the prevalence of the disease in regions traditionally believed to have a low prevalence, while, at the same time, prevention and screening programs in endemic regions have reduced the number of affected individuals. Various approaches to prevention and screening have been used. Region‐specific prevention and treatment programs, customized to align with local healthcare resources and cultural values, have been effective in identifying patients and carriers and providing information and care. Significant challenges remain in universally implementing these programs.
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Citations
Cites
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Self-citationPhenotype-genotype relationships in monogenic disease: lessons from the thalassaemias
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Cited by
Taher, A. T., Musallam, K. M., & Cappellini, M. D. (2021) · New England Journal of Medicine · doi:10.1056/nejmra2021838 · Cited by 477
Kattamis, A., Kwiatkowski, J. L., & Aydinok, Y. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00536-0 · Cited by 313
Self-citationTuo, Y., Li, Y., Li, Y., Ma, J., Yang, X., Wu, S., Jin, J., & He, Z. (2024) · eClinicalMedicine · doi:10.1016/j.eclinm.2024.102619 · Cited by 283
Fu, Y.-K., Liu, H.-M., Lee, L.-H., Chen, Y.-J., Chien, S.-H., Lin, J.-S., Chen, W.-C., Cheng, M.-H., Lin, P.-H., Lai, J.-Y., et al. (2021) · Diagnostics · doi:10.3390/diagnostics11091725 · Cited by 38
Metadata
- Authors
- Kattamis, A., Forni, G. L., Aydinok, Y., & Viprakasit, V.
- Venue
- European Journal of Haematology
- Publisher
- Wiley
- Published
- 2020-09-21
- Volume
- 105
- Issue
- 6
- Pages
- 692-703
- ISSN
- 0902-4441 (ISSN-L)
- 1600-0609
- OpenAlex
- W3083542131
- Cited by
- 331
- References
- 50
- FWCI
- 13.33
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Kattamis, A., Forni, G. L., Aydinok, Y., & Viprakasit, V. (2020). Changing patterns in the epidemiology of β‐thalassemia. European Journal of Haematology. https://doi.org/10.1111/ejh.13512
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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