The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.
Post‐stroke cognitive decline: an update and perspectives for clinical research
Abstract
The close relationship between stroke and dementia is an important health issue. Ischaemic stroke can facilitate the onset of vascular dementia as well as aggravate pre‐existing cognitive decline. The onset of cognitive decline may become manifest immediately following the onset of ischaemic stroke, but often there is a delay in the development of cognitive decline after a stroke. This delay can be seen as a therapeutic time window allowing interventions to be applied to preserve cognition following stroke. Both neurodegenerative and vascular mechanisms are activated and probably result in overlapping processes within the neurovascular unit. This review focuses on the incidence and prevalence of cognitive decline following stroke, predisposing stroke aetiologies, pre‐stroke decline, imaging factors and biomarkers. Outcomes are discussed in relation to timing of assessment and neuropsychological tests used for evaluation of cognitive decline in ischaemic stroke patients. Including such tests in routine evaluations of stroke patients after some weeks or months is recommended. Finally, an outlook on ongoing and planned intervention trials is added and some recommendations for future research are proposed.
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Cited by
El Husseini, N., Katzan, I. L., Rost, N. S., Blake, M. L., Byun, E., Pendlebury, S. T., Aparicio, H. J., Marquine, M. J., Gottesman, R. F., Smith, E. E., et al. (2023) · Stroke · doi:10.1161/str.0000000000000430 · Cited by 539
Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice
Cuartero, M. I., de la Parra, J., Pérez-Ruiz, A., Bravo-Ferrer, I., Durán-Laforet, V., García-Culebras, A., García-Segura, J. M., Dhaliwal, J., Frankland, P. W., Lizasoain, I., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci120412 · Cited by 128
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Metadata
- Authors
- Brainin, M., Tuomilehto, J., Heiss, W. ‐., Bornstein, N. M., Bath, P. M. W., Teuschl, Y., Richard, E., Guekht, A., Quinn, T., & the Post Stroke Cognition Study Group
- Venue
- European Journal of Neurology
- Publisher
- Wiley
- Published
- 2014-12-09
- Volume
- 22
- Issue
- 2
- Pages
- 229
- ISSN
- 1351-5101 (ISSN-L)
- 1468-1331
- OpenAlex
- W2016656479
- Cited by
- 253
- References
- 119
- FWCI
- 9.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Post‐stroke cognitive decline: an update and perspectives for clinical research. https://app.cochat.ai/papers/10.1111/ene.12626
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- Brainin, M., Tuomilehto, J., Heiss, W. ‐., Bornstein, N. M., Bath, P. M. W., Teuschl, Y., Richard, E., Guekht, A., Quinn, T., & the Post Stroke Cognition Study Group. (2015). Post‐stroke cognitive decline: an update and perspectives for clinical research. European Journal of Neurology. https://doi.org/10.1111/ene.12626
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
