Cited by 316Psychosomatic Disorders and Their TreatmentsEpilepsy research and treatmentPain Management and Placebo Effect

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Management of psychogenic nonepileptic seizures

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LaFrance, W. Curt, Reuber, Markus, Goldstein, Laura H.·2013·Epilepsia

DOI 10.1111/epi.12106

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Abstract

The International League Against Epilepsy (ILAE) Neuropsychobiology Commission gave the charge to provide practical guidance for health professionals for the pharmacologic and nonpharmacologic treatment of patients with psychogenic nonepileptic seizures (PNES). Using a consensus review of the literature, an international group of clinician-researchers in epilepsy, neurology, neuropsychology, and neuropsychiatry evaluated key management approaches for PNES. These included the following: presentation of the diagnosis, early phase treatment, psychological and pharmacologic interventions, and maintenance management. The aim of this report is to provide greater clarity about the range and current evidence base for treatment for patients with PNES, with the intention of improving the care of patients with PNES and patients who develop PNES as a comorbidity of epilepsy.

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Authors: LaFrance, W. C., Reuber, M., & Goldstein, L. H.
Affiliations: Neuropsychiatry and Behavioral Neurology Division Rhode Island Hospital Brown University, Alpert Medical School Providence Rhode Island U.S.A
Royal Hallamshire Hospital (GB)
King's College London (GB)
ORCID: Reuber, Markus
Goldstein, Laura H.
Venue: Epilepsia
Publisher: Wiley
Published: 2013-03
Volume: 54
Issue: s1
Pages: 53-67
ISSN: 0013-9580 (ISSN-L)
1528-1167
DOI: 10.1111/epi.12106
OpenAlex: W2170302766
Cited by: 316
References: 140
Citations by year: 2026: 12 · 2025: 12 · 2024: 15 · 2023: 13 · 2022: 13 · 2021: 19 · 2020: 30 · 2019: 18 · 2018: 67 · 2017: 26 · 2016: 34 · 2015: 30 · 2014: 23 · 2013: 4
FWCI: 4.14
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 3 d)
Locations: Epilepsia (publishedVersion)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
Keywords: psychogenic non-epileptic seizures, pharmacotherapy, non-pharmacological treatment, psychological intervention, maintenance management, epilepsy comorbidity, treatment guidelines
MeSH terms: Antidepressive Agents, Communication, Electroencephalography, Humans, Physician-Patient Relations, Psychotherapy, Seizures, Somatoform Disorders, Cognitive Behavioral Therapy, Practice Guidelines as Topic

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