All roads lead to PP 2A: exploiting the therapeutic potential of this phosphatase

Cited by (311)

Items 101–200 of 311

1. PP2A and cancer epigenetics: a therapeutic opportunity waiting to happen
   Samantha L. Tinsley, Brittany L. Allen-Petersen · 2022 · NAR Cancer
2. IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A
   Takumi Ueda, Yuri Kohama, Hiroshi Sakurai · 2018 · Cellular Signalling
3. Targeting protein phosphatase PP2A for cancer therapy: development of allosteric pharmaceutical agents
   David L. Brautigan, Caroline C. Farrington, Goutham Narla · 2021 · Clinical Science
4. Additive renal protective effects between arctigenin and puerarin in diabetic kidney disease
   Xueling Li, Jue Wang, Jiayi Yan, Cijiang He, Yi Li, Yifei Zhong · 2024 · Biomedicine & Pharmacotherapy
5. Microtubules in Polyomavirus Infection
   Lenka Horníková, Kateřina Bruštíková, Jitka Forstová · 2020 · Viruses
6. Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
   Sahar Mazhar, Daniel Léonard, Alejandro Sosa, Daniela Schlatzer, Dafydd Thomas, Goutham Narla · 2020 · Cell Reports
7. Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype
   Elham Kashani, Erik Vassella · 2022 · Cancers
8. Crystal structure of the human Tip41 orthologue, TIPRL, reveals a novel fold and a binding site for the PP2Ac C-terminus
   Valéria Scorsato, Tatiani B. Lima, Germanna Lima Righetto, Nilson Ivo Tonin Zanchin, J. Brandão-Neto, James Sandy, H.M. Pereira, A. Ferrari, Fabio Cesar Gozzo, Juliana Helena Costa Smetana et al. · 2016 · Scientific Reports
9. Spinocerebellar ataxia type 12: An update
   Achal Kumar Srivastava, Deepak Kumar, Mohammad Faruq, VarunR Gundluru · 2019 · Annals of Movement Disorders
10. TGF-β1 maintains Foxp3 expression and inhibits glycolysis in natural regulatory T cells via PP2A-mediated suppression of mTOR signaling
    Xuelu Chen, Feng Li, Shengfu Li, Dan Long, Juan Shan, Youping Li · 2020 · Immunology Letters
11. Oncogenic RAS promotes MYC protein stability by upregulating the expression of the inhibitor of apoptosis protein family member Survivin
    Wen-Hsuan Chang, Yinzhe Liu, Emma A. Hammes, Kirsten L. Bryant, Richard A. Cerione, Marc A. Antonyak · 2022 · Journal of Biological Chemistry
12. Spinocerebellar ataxia type 12: clues to pathogenesis
    Rachael L. Cohen, Russell L. Margolis · 2016 · Current Opinion in Neurology
13. Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies
    Simon McKenzie-Nickson, Jacky Chan, Keyla A. Perez, Lin Wai Hung, Lesley Cheng, Amelia Sedjahtera, Lydia Gunawan, Paul Anthony Adlard, David J. Hayne, Lachlan E. McInnes et al. · 2018 · ACS Chemical Neuroscience
14. Protein phosphatase 2 regulatory subunit B''Alpha silencing inhibits tumor cell proliferation in liver cancer
    Huijuan Chen, Jing Xu, Peixiao Wang, Qingming Shu, Lihong Huang, Jìng Guo, Xuyi Zhang, Hongying Zhang, Ying Wang, Zhongyang Shen et al. · 2019 · Cancer Medicine
15. Vitamin D Attenuates Alzheimer-like Pathology Induced by Okadaic Acid
    Yiming Pan, Yalin Zhang, Ning Liu, Wanyi Lu, Jingxin Yang, Ye Li, Zuwang Liu, Yinghong Wei, Yan Lou, Juan Kong · 2021 · ACS Chemical Neuroscience
16. RETRACTED: Neuroprotective Effect of Protein Phosphatase 2A/Tristetraprolin Following Subarachnoid Hemorrhage in Rats
    Jian Yin, Ran Li, Wenchao Liu, Yunchang Chen, Xin Zhang, Xifeng Li, Xuying He, Chuanzhi Duan · 2018 · Frontiers in Neuroscience · Retracted
17. Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis
    Meghna Kataria, Hiroyuki Yamano · 2019 · Cells
18. Phosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
    Anne Slomp, Laura M Moesbergen, Eric Eldering, Marie José Kersten, Monique C. Minnema, Victor Peperzak · 2021 · Cell Death and Disease
19. Zinc in Regulating Protein Kinases and Phosphatases in Neurodegenerative Diseases
    Hui-Liang Zhang, Xiaochuan Wang, Rong Liu · 2022 · Biomolecules
20. Phosphatases and solid tumors: focus on glioblastoma initiation, progression and recurrences
    Matthias Dedobbeleer, Estelle Willems, Stephen D. Freeman, Arnaud Lombard, Nicolas Goffart, Bernard Rogister · 2017 · Biochemical Journal
21. MHC Phosphopeptides: Promising Targets for Immunotherapy of Cancer and Other Chronic Diseases
    Keira E. Mahoney, Jeffrey Shabanowitz, Donald F. Hunt · 2021 · Molecular & Cellular Proteomics
22. The mechanism of AKT activation in cancer
    Fei Meng, Huiyan Li, Yijie Wang, Zhiming Zheng, Yan Chen · 2025 · Cell investigation.
23. Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model
    Sean Miller, Jenna C. Glatzer, Yi-chun Hsieh, Jeffrey D. Rothstein · 2018 · Journal of Neurogenetics
24. PP2A-B56γ is required for an efficient spindle assembly checkpoint
    Prajakta A. Varadkar, Fatima Abbasi, Kazuyo Takeda, Jade J. Dyson, Brent McCright · 2017 · Cell Cycle
25. Identification of PP2A/Set Binding Sites and Design of Interacting Peptides with Potential Clinical Applications
    Lu Tian, XG Zhang, Dorien Haesen, Jerónimo Bravo, Jesús M. Fominaya, Sylvain Choquet, Jean Marc Zini, Séverine Loisel, Etienne Waelkens, Veerle Janssens et al. · 2017 · International Journal of Peptide Research and Therapeutics
26. Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus
    Katiuska González‐Arzola, Alejandra Guerra‐Castellano, Francisco Rivero‐Rodríguez, Miguel Á. Casado‐Combreras, Gonzalo Pérez‐Mejías, Antonio Dı́az-Quintana, Irene Díaz‐Moreno, Miguel Ángel De la Rosa · 2021 · FEBS Open Bio
27. Hypoxia modulates protein phosphatase 2A through HIF‐1α dependent and independent mechanisms in human aortic smooth muscle cells and ventricular cardiomyocytes
    Ismail Suliman Elgenaidi, Paul Spiers · 2019 · British Journal of Pharmacology
28. SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma
    Iris Sze Ue Luk, Caroline M. Bridgwater, Angela Y. C. Yu, Liberalis Debraj Boila, Mariana Yáñez-Bartolomé, Aaron Lampano, Taylor S. Hulahan, Myriam Boukhali, Meena Kathiresan, Teresa Mercade Macarulla et al. · 2024 · Science Translational Medicine
29. Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities
    Nicola M. Sergienko, Daniel G. Donner, Lea M.D. Delbridge, Julie R. McMullen, Kate L. Weeks · 2021 · Cellular Signalling
30. Drug-resistant exosome miR-99b-3p induces macrophage polarization and confers chemoresistance on sensitive cells by targeting PPP2CA
    Huilan Mao, Ruyin Ye, Guohui Tang, Shuang Tao, Ke Wei, Yulun Wu, Siyan Pang, Jing Wang, Jiwen Shi, Yuxin Ji et al. · 2024 · International Immunopharmacology
31. The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells
    Qian Zeng, Fangfang Jin, Husun Qian, Hongling Chen, Yange Wang, Dian Zhang, Yu Wei, Tingmei Chen, Bianqin Guo, Chengsen Chai · 2021 · Carcinogenesis
32. Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance
    Reyaz ur Rasool, Caitlin M. O’Connor, Chandan Kanta Das, Mohammed Alhusayan, Brijesh Kumar Verma, Sehbanul Islam, Ingrid E. Frohner, Qu Deng, Erick Mitchell-Velasquez, Jaya Sangodkar et al. · 2023 · Nature Communications
33. Identification and characterization of novel enhanced cell penetrating peptides for anti-cancer cargo delivery
    XG Zhang, Jean Yves Brossas, Christophe Parizot, Jean Marc Zini, Angelita Rebollo · 2017 · Oncotarget
34. Prognostic significance of CIP2A expression in solid tumors: A meta-analysis
    Min Tang, Jiaofeng Shen, Ping Li, Li-Na Zhou, Ping Zeng, Xixi Cui, Min‐Bin Chen, Ye Tian · 2018 · PLoS ONE
35. Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells
    Ganesh babu Manoharan, Sunday Okutachi, Daniel Abankwa · 2022 · PLoS ONE
36. Protein phosphatase 2A mediates JS‐K‐induced apoptosis by affecting Bcl‐2 family proteins in human hepatocellular carcinoma HepG2 cells
    Ling Liu, Zile Huang, Jingjing Chen, Jiangang Wang, Shuying Wang · 2018 · Journal of Cellular Biochemistry
37. MID1 and MID2 regulate cell migration and epithelial-mesenchymal transition via modulating Wnt/β-catenin signaling
    Yingying Qiao, Yuan Zhou, Chao Song, Xin Zhang, Yi Zou · 2020 · Annals of Translational Medicine
38. Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options
    Jesús González Bosquet, Qing Zhang, William A. Cliby, Jamie Nadine Bakkum-Gamez, Ling Cen, Sean Christopher Dowdy, Mark E. Sherman, S. John Weroha, Amy C. Clayton, Benjamin R. Kipp et al. · 2021 · PLoS ONE
39. PP2A‐B55 and its adapter proteins IER2 and IER5 regulate the activity of RB family proteins and the expression of cell cycle‐related genes
    Kuriko Doi, Hiroto Takeuchi, Hiroshi Sakurai · 2022 · FEBS Journal
40. Inhibition of PP2A ameliorates intervertebral disc degeneration by reducing annulus fibrosus cells apoptosis via p38/MAPK signal pathway
    Pengfei Zhu, Xiexing Wu, Li Ni, Kai Chen, Zhongchen Dong, Jiacheng Du, Fanchen Kong, Yubo Mao, Huaqiang Tao, Miao Chu et al. · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
41. Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways
    Stefania Livia Ciummo, Carlo Sorrentino, Cristiano Fieni, Emma Di Carlo · 2023 · Journal of Experimental & Clinical Cancer Research
42. 27-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells
    Liming Ma, Zirui Liang, Keren Zhou, Hui Zhou, Liang‐Hu Qu · 2016 · Biochemical and Biophysical Research Communications
43. Ketamine, a Clinically Used Anesthetic, Inhibits Vascular Smooth Muscle Cell Proliferation via PP2A-Activated PI3K/Akt/ERK Inhibition
    Yi Fang Chang, Jiun-Yi Li, Thanasekaran Jayakumar, Shou-Huang Hung, Wei-Cheng Lee, Manjunath Manubolu, Joen‐Rong Sheu, Ming‐Jen Hsu · 2017 · International Journal of Molecular Sciences
44. PP2A as the Main Node of Therapeutic Strategies and Resistance Reversal in Triple-Negative Breast Cancer
    Henan Zhao, Duojiao Li, Baojing Zhang, Yan Qi, Yun-Peng Diao, Yuhong Zhen, Xiaohong H. Shu · 2017 · Molecules
45. Protein phosphatase 2A controls ongoing DNA replication by binding to and regulating cell division cycle 45 (CDC45)
    Abbey L. Perl, Caitlin M. O’Connor, Pengyan Fa, Franklin Mayca Pozo, Junran Zhang, Youwei Zhang, Goutham Narla · 2019 · Journal of Biological Chemistry
46. PP2A and E3 ubiquitin ligase deficiencies: Seminal biological drivers in endometrial cancer
    Jesús González Bosquet, Jamie Nadine Bakkum-Gamez, Amy L. Weaver, Michaela E. McGree, Sean Christopher Dowdy, Abimbola O. Famuyide, Benjamin R. Kipp, Kevin C. Halling, Fergus J. Couch, Karl C. Podratz · 2021 · Gynecologic Oncology
47. Cooperative mechanics of PR65 scaffold underlies the allosteric regulation of the phosphatase PP2A
    Burak Kaynak, Zakaria Larbi Dahmani, Pemra Doruker, Anupam Banerjee, Shang-Hua Yang, Reuven Gordon, Laura S. Itzhaki, İvet Bahar · 2023 · Structure
48. Protein phosphatase 2A Aα regulates Aβ protein expression and stability
    Caitlin M. O’Connor, Matthew T. Hoffa, Sarah E. Taylor, Rita A. Avelar, Goutham Narla · 2019 · Journal of Biological Chemistry
49. PP2Ac upregulates PI3K-Akt signaling and induces hepatocyte apoptosis in liver donor after brain death
    Yan Xiong, Jianan Lan, Kaixin Huang, Yaruo Zhang, Lewei Zheng, Yanfeng Wang, Qifa Ye · 2019 · APOPTOSIS
50. Biology of the adenovirus E4orf4 protein: from virus infection to cancer cell death
    Tamar Kleinberger · 2019 · FEBS Letters
51. PP2A Phosphatase as an Emerging Viral Host Factor
    M.S. Barski, Jordan James Minnell, Goedele N. Maertens · 2021 · Frontiers in Cellular and Infection Microbiology
52. RHOB expression controls the activity of serine/threonine protein phosphatase PP2A to modulate mesenchymal phenotype and invasion in non-small cell lung cancers
    Olivier Calvayrac, Anne Pradines, Gilles Favre · 2016 · Small GTPases
53. CUL4B mutations impair human cortical neurogenesis through PP2A-dependent inhibition of AKT and ERK
    Yanyan Ma, Xiaolin Liu, Min Zhou, Wenjie Sun, Baichun Jiang, Qiao Liu, Μolin Wang, Yongxin Zou, Qiji Liu, Yaoqin Gong et al. · 2024 · Cell Death and Disease
54. Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis
    Guy Nadel, Zhong Yao, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Tamar Bar Ziv, Zvi Naor, Arie Admon, Rony Seger · 2024 · Cell Communication and Signaling
55. PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses
    Yetunde Makinwa, Brian M. Cartwright, Phillip R. Musich, Zhengke Li, Himadri Biswas, Yue Zou · 2020 · Frontiers in Cell and Developmental Biology
56. Cataloguing the phosphorylation sites of tristetraprolin (TTP): Functional implications for inflammatory diseases
    Maria C. Rezcallah, Juhura G. Almazi, Alaina Jean Ammit · 2020 · Cellular Signalling
57. Cinnamaldehyde and Curcumin Prime Akt2 for Insulin-Stimulated Activation
    Yasuyo Urasaki, Thuc T. Le · 2022 · Nutrients
58. The Neurospora crassa PP2A Regulatory Subunits RGB1 and B56 Are Required for Proper Growth and Development and Interact with the NDR Kinase COT1
    Hila Shomin-Levi, Oded Yarden · 2017 · Frontiers in Microbiology
59. Abortive Infection of Animal Cells: What Goes Wrong
    Aaron Embry, Don B. Gammon · 2024 · Annual Review of Virology
60. The prognostic value of Cyclin-Dependent Kinase 5 and Protein Phosphatase 2A in Gastric Cancer
    Jian-Xian Lin, Xinsheng Xie, Xiong‐Feng Weng, Chao‐Hui Zheng, Jian‐Wei Xie, Jia-Bin Wang, Jun Lu, Qi‐Yue Chen, Long‐Long Cao, Mi Lin et al. · 2018 · Journal of Cancer
61. Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma
    Caitlin M. O'Connor, Sarah E. Taylor, Kathryn Miller, Lauren Hurst, Terrance James Haanen, Tahra K. Suhan, Kaitlin P. Zawacki, Fallon K. Noto, Jonida Trako, Arathi Mohan et al. · 2021 · Cancer Research
62. Thirty years of SET/TAF1β/I2PP2A: from the identification of the biological functions to its implications in cancer and Alzheimer’s disease
    Antonella Di Mambro, Maria Teresa Esposito · 2022 · Bioscience Reports
63. Aralkyl selenoglycosides and related selenosugars in acetylated form activate protein phosphatase-1 and -2A
    Zoltán Kónya, Bálint Bécsi, Andrea Kiss, István Tamás, Beáta Lontay, László Sz. Szilágyi, Katalin E. Kövér, Ferenc Erdődi · 2018 · Bioorganic & Medicinal Chemistry
64. Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases—Just the Beginning
    Yavar Shiravand, Ulrich Walter, Kerstin Jurk · 2021 · Hämostaseologie
65. High fructose induces dysfunctional vasodilatation via PP2A-mediated eNOS Ser1177 dephosphorylation
    Jiaqi Jin, Jingya Liu, Yong Ming Luo, Hong He, Xinyue Zheng, Chaoyang Zheng, Yi Huang, Yang Chen · 2022 · Nutrition & Metabolism
66. Ethanolic Extract of Polygonum minus Protects Differentiated Human Neuroblastoma Cells (SH-SY5Y) against H2O2-Induced Oxidative Stress
    Nor Hafiza Sayuti, Nabilah Zulkefli, Jen Kit Tan, Norazalina Saad, Syarul Nataqain Baharum, Hamizah Shahirah Hamezah, Hamidun Bunawan, Qamar Uddin Ahmed, Humaira Parveen, Sayeed Mukhtar et al. · 2023 · Molecules
67. A protein phosphatase 1 specific phos phatase ta rgeting p eptide (PhosTAP) to identify the PP1 phosphatome
    Meng Shyan Choy, Hieu Thi Nguyen, Ganesan Senthil Kumar, Wolfgang Peti, Arminja Nadine Kettenbach, Rebecca Page · 2024 · Proceedings of the National Academy of Sciences
68. Roles of I2PP2A in the downregulation of eNOS Ser1177 phosphorylation by angiotensin II-activated PP2A
    Yanbei Luo, Qian Zhang, Jing Ding, Min Yu, Juncai Jiang, Fei Yang, Shengnan Wang, Alei Wang, Lingxiao Wang, Shan Wu et al. · 2019 · Biochemical and Biophysical Research Communications
69. Inhibiting PP2Acα Promotes the Malignant Phenotype of Gastric Cancer Cells through the ATM/METTL3 Axis
    Zhaoxiang Cheng, Shan Gao, Xiaojie Liang, Chao Lian, Jianquan Chen, Chao Fang · 2021 · BioMed Research International
70. TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer
    Célie Cokelaere, Rüveyda Dok, Emanuela Elsa Cortesi, Peihua Zhao, Anna A. Sablina, Sandra Nuyts, Rita Derua, Veerle Janssens · 2023 · Cellular Oncology
71. New Insights into Platelet Signalling Pathways by Functional and Proteomic Approaches
    Kerstin Jurk, Ulrich Walter · 2018 · Hämostaseologie
72. The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
    Wesal Habbab, Imad Aoudé, Freshteh Palangi, Sara Abdulla, Tariq Ahmed · 2019 · International Journal of Molecular Sciences
73. Fingolimod Phosphate (FTY720-P) Activates Protein Phosphatase 2A in Human Monocytes and Inhibits Monosodium Urate Crystal–Induced Interleukin-1β Production
    Marwa M. Qadri, Sandy Elsayed, Khaled A. Elsaid · 2020 · Journal of Pharmacology and Experimental Therapeutics
74. Synaptotagmin 1-mediated cell membrane penetration and dopamine release enhancement by latroeggtoxin-VI
    Xiaochao Tang, Dianmei Yu, Haiyan Wang, Zhixiang Lei, Yiwen Zhai, Minglu Sun, Si Chen, Ying Wang, Zhen Liu, Weijun Hu et al. · 2022 · International Journal of Biological Macromolecules
75. From Basic Science to Clinical Practice: The Role of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A)/p90 in Cancer
    Beibei Chen, Huihui Hu, Xiaobing Chen · 2023 · Frontiers in Genetics
76. The next decade of SET: from an oncoprotein to beyond
    Han Yao, Meng Zhang, Donglai Wang · 2023 · Journal of Molecular Cell Biology
77. All eyes on Eya: A unique transcriptional co-activator and phosphatase in cancer
    Connor J. Hughes, Christopher Alderman, Arthur Wolin, Kaiah M. Fields, Rui Zhao, H. Ford · 2024 · Biochimica et biophysica acta. Reviews on cancer
78. Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens
    Victor Clausse, Dingyin Tao, Subrata Debnath, Yuhong Fang, Harichandra D. Tagad, Yuhong Wang, Hongmao Sun, Christopher A. LeClair, Sharlyn J. Mazur, Kelly C. Lane et al. · 2019 · Journal of Biological Chemistry
79. Emerging Roles of B56 Phosphorylation and Binding Motif in PP2A-B56 Holoenzyme Biological Function
    Yanqiao Zhang, Haonan Jiang, Haimeng Yin, Xinyuan Zhao, Yali Zhang · 2024 · International Journal of Molecular Sciences
80. Role of Protein Phosphatases in Tumor Angiogenesis: Assessing PP1, PP2A, PP2B and PTPs Activity
    Márton Fonódi, Lilla Nagy, Anita Boratkó · 2024 · International Journal of Molecular Sciences
81. Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm
    Xianming Zhou, Chao Zhang, Fei Xie, Wei Wei, Rui Li, Qian Xu, Yu Wang, Philip A. Klenotic, Goutham Narla, Nianguo Dong et al. · 2021 · Clinical Science
82. Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1
    Liping Chen, Ping Guo, Wenxue Li, Xinhang Jiang, Qun Zhao, Daochuan Li, Qing Wang, Yongmei Xiao, Xiumei Xing, Yaqin Pang et al. · 2022 · Journal of Biological Chemistry
83. A SMAP in the face for cancer
    Shirish Shenolikar · 2017 · Journal of Clinical Investigation
84. The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets
    Stephanie Makhoul, Elena J. Kumm, Pengyu Zhang, Ulrich Walter, Kerstin Jurk · 2020 · International Journal of Molecular Sciences
85. Competition between two phosphatases fine-tunes Hedgehog signaling
    Min Liu, Aiguo Liu, Jie Wang, Yansong Zhang, Yajuan Li, Ying Su, Alan Jian Zhu · 2020 · The Journal of Cell Biology
86. Protein Phosphatase 2A Regulates Phenotypic and Metabolic Alteration of Microglia Cells in HFD-Associated Vascular Dementia Mice via TNF-α/Arg-1 Axis
    Md Nematullah, Faraz Rashid, Shwetanjali Nimker, Farah Khan · 2023 · Molecular Neurobiology
87. Influence of point mutations on PR65 conformational adaptability: Insights from molecular simulations and nanoaperture optical tweezers
    Anupam Banerjee, Samuel Mathew, Mohsin M. Naqvi, Sema Zeynep Yilmaz, Maria Zacharopoulou, Pemra Doruker, Janet R. Kumita, Shang-Hua Yang, Mert Gür, Laura S. Itzhaki et al. · 2024 · Science Advances
88. KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development
    Samantha L. Tinsley, Ella Rose D. Chianis, Rebecca A. Shelley, Gaganpreet K. Mall, Alisha Dhiman, Garima Baral, Harish Kothandaraman, Mary C. Thoma, Isabel A. English, Colin J. Daniel et al. · 2024 · Oncogene
89. Direct observation of small molecule activator binding to single PR65 protein
    Annie Yang-Schulz, Maria Zacharopoulou, Sema Zeynep Yilmaz, Anupam Banerjee, Satyaki Saha, Daniel Nietlispach, Michael H. J. Ohlmeyer, Mert Gür, Laura S. Itzhaki, İvet Bahar et al. · 2025 · npj Biosensing
90. An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells
    Raquel L. Arribas, Anna Bordas, Judit Domènech Omella, José Luis Cedillo, Veerle Janssens, Carmen Montiel, Cristóbal de los Rı́os · 2020 · Bioorganic Chemistry
91. eIF3a‐PPP2R5A‐mediated ATM/ATR dephosphorylation is essential for irinotecan‐induced DNA damage response
    Chao Mei, Zeen Sun, Li‐Ming Tan, Jianping Gong, Xi Li, Zhaoqian Liu · 2022 · Cell Proliferation
92. Protein Phosphatase 2a Inhibits Gastric Cancer Cell Glycolysis by Reducing MYC Signaling
    Zhenhua Cai, Wei Zhang, Ruiqing Zhou, Yuhong Wang, Yunzhang Feng, Yunzhang Feng · 2022 · Cell Biochemistry and Biophysics
93. Cancerous Inhibitor of Protein Phosphatase 2A as a Molecular Marker for Aggressiveness and Survival in Oral Squamous Cell Carcinoma
    Rajab A. Alzahrani, Amani Ahmed Alrehaili, Amal Fathi Gharib, Farah Anjum, Khadiga Ahmed Ismail, Wael H. Elsawy · 2020 · Journal of Cancer Prevention
94. Sensitive Detection of Oral Leukoplakia: Analyzing P90 Biomarkers in Saliva and Tissue
    Hsiao-Hsuan Wan, Haochen Zhu, Chao-Ching Chiang, Jian-Sian Li, Fan Ren, Cheng-Tse Tsai, Yu‐Te Liao, Dan W. Neal, Joseph Katz, Josephine F. Esquivel‐Upshaw · 2024 · Biosensors
95. Efficacy of an anti-cancer strategy targeting SET in canine osteosarcoma
    Shunya Tsuji, Takashi Ohama, Takayuki Nakagawa, Koichi Sato · 2019 · Journal of Veterinary Medical Science
96. PP2A-C may be a promising candidate for postmortem interval estimation
    Jing Wang, Gang Chen, Hongyan Qian, Qing Shang, Jing Xiao, Min Liang, Baoyao Gao, Tao Li, Xinshe Liu · 2021 · International Journal of Legal Medicine
97. The Interaction Mechanism of Intrinsically Disordered PP2A Inhibitor Proteins ARPP-16 and ARPP-19 With PP2A
    Chandan J. Thapa, Pekka Roivas, Tatu Haataja, Perttu Permi, Ulla Pentikäinen · 2021 · Frontiers in Molecular Biosciences
98. Combination of dasatinib and okadaic acid induces apoptosis and cell cycle arrest by targeting protein phosphatase PP2A in chronic myeloid leukemia cells
    Buket Özel, Sezgi Kıpçak, Çığır Biray Avcı, Cumhur Gündüz, Güray Saydam, Çağdaş Aktan, Nur Selvi Günel · 2022 · Medical Oncology
99. Identification of a novel polyomavirus from a marsupial host
    M. Dunowska, M. Perrott, P. Biggs · 2022 · Virus Evolution
100. Metformin alleviates lung-endothelial hyperpermeability by regulating cofilin-1/PP2AC pathway
     Mohammad R. Siddiqui, Narsa M. Reddy, Hafeez M. Faridi, Mohd Shahid, Thomas P. Shanley · 2023 · Frontiers in Pharmacology