All roads lead to PP 2A: exploiting the therapeutic potential of this phosphatase

Cited by (311)

Items 201–300 of 311

1. PP2A plays a key role in inflammation and cancer through tristetraprolin activation
   Ion Cristóbal, Blanca Torrejón, Juan Madoz‐Gúrpide, Federico Rojo, Jesús García‐Foncillas · 2016 · Annals of the Rheumatic Diseases
2. Targeting phosphatases in cancer: suppression of many versus the ablation of one
   Brandon M. D’Arcy, Aishwarya Prakash, Richard E. Honkanen · 2019 · Oncotarget
3. Small-molecule modulators of B56-PP2A restore 4E-BP function to suppress eIF4E-dependent translation in cancer cells
   Michelle A. Lum, Kayla A. Jonas, Shreya Parmar, Adrian R. Black, Caitlin M. O’Connor, Stephanie Dobersch, Naomi Yamamoto, Tess M. Robertson, Aidan Schutter, Miranda Giambi et al. · 2025 · Journal of Clinical Investigation
4. PPP2R2A insufficiency enhances PD-L1 immune checkpoint blockade efficacy in lung cancer through cGAS-STING activation
   Zhaojun Qiu, No Joon Song, Anqi Li, Deepika Singh, Chandra Bhushan Prasad, Chunhong Yan, David Paul Carbone, Qi-En Wang, Xiaoli Zhang, Zihai Li et al. · 2025 · Journal of Clinical Investigation
5. Metformin Inhibits Inflammation by Targeting the NLRP3 Inflammasome: Linking NF-κB/NEK7/AMPK Signaling to Mitochondrial Function
   Dingyi Ning, Chenxin Jiang, Jiangyan Zeng, Fanyun Zeng, Xuehong Zheng, Panpan Xia, Yunkun Liu, Xin Huang (11077), Deju Zhang, Xiao Liu et al. · 2026 · Journal of Inflammation Research
6. High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation
   Jiajia He, Lei Shang, Qun-Wei Yu, Ning Jiao, Shuang Qiu, Wei-Xiong Zhu, Dong-Feng Wu, Yun-Er Tian, Qing Zhang · 2021 · World Journal of Gastrointestinal Oncology
7. Targeting T-type channels in cancer: What is on and what is off?
   Anna Visa, Lía Alza, Adrián Casas-Benito, Judit Herreros, Carles Cantı́ · 2021 · Drug Discovery Today
8. ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer
   Jesús González Bosquet, S. John Weroha, Jamie Nadine Bakkum-Gamez, Amy L. Weaver, Michaela E. McGree, Sean Christopher Dowdy, Abimbola O. Famuyide, Benjamin R. Kipp, Kevin C. Halling, Siddhartha Yadav et al. · 2022 · PLoS ONE
9. Biochemical characterization of the Eya and PP2A-B55α interaction
   Christopher Alderman, Ryan Anderson, Lingdi Zhang, Connor J. Hughes, Xueni Li, Chris Ebmeier, Marisa E. Wagley, Natalie G. Ahn, Heide L. Ford, Rui Zhao · 2024 · Journal of Biological Chemistry
10. Urolithin A attenuates hexavalent chromium-induced small intestinal injury by modulating PP2A/Hippo/YAP1 pathway
    Ping Guo, Rongfang Yang, Shiyuan Zhong, Yingying Ding, Jingnan Wu, Ziwei Wang, Huiqi Wang, Jiaxin Zhang, Nannan Tu, Hongwei Zhou et al. · 2024 · Journal of Biological Chemistry
11. Miklós Bodanszky Award Lecture: Advances in the selective targeting of protein phosphatase‐1 and phosphatase‐2A with peptides
    Maja Köhn · 2017 · Journal of Peptide Science
12. A comprehensive in silico analysis of huntingtin and its interactome
    Valentina Brandi, Valentina Di Lella, Maria Marino, Paolo Ascenzi, Fabio Polticelli · 2017 · Journal of Biomolecular Structure and Dynamics
13. Protein phosphatase 2A regulated by USP7 is polyubiquitinated and polyneddylated
    Hyeon‐Ah Do, Kwang‐Hyun Baek · 2022 · Oncology Reports
14. Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets
    Qian Guo, Gang Wu, Fang Huang, Zhen Cheng Wei, Jian‐Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Honglian Li · 2022 · Aging
15. PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling
    Liesbeth Guffens, Rita Derua, Veerle Janssens · 2023 · Cell Death Discovery
16. Role of protein phosphatase 2A in PTTH-stimulated prothoracic glands of the silkworm, Bombyx mori
    Shi‐Hong Gu, Chien‐Hung Chen, Pei‐Ling Lin, Hsiao-Yen Hsieh · 2019 · General and Comparative Endocrinology
17. Protein Phosphatases: A Neglected Target Family for Drug Discovery
    Joe Lewis, Gerhard Müller · 2022 · CHIMIA International Journal for Chemistry
18. Protein Phosphatase Signaling in Cardiac Myocytes
    Danielle Abdallah, Nipun Malhotra, Mona El Refaey · 2022 · Springer eBooks
19. PPP2R1A mutation status as a predictive and prognostic factor in molecularly characterized endometrial carcinoma: a cohort study
    Masuma Khatun, Annukka M. Pasanen, Anna Kanerva, Riitta Koivisto-Korander, Taru Tuomi, Ralf C. Bützow, Mikko J. Loukovaara · 2025 · International Journal of Gynecological Cancer
20. Preterm birth alters the feeding-induced activation of Akt signaling in the muscle of neonatal piglets
    Agus Suryawan, Marko Rudar, Jane Naberhuis, Marta L. Fiorotto, Teresa A. Davis · 2022 · Pediatric Research
21. White spot syndrome virus hijacks host PP2A-FOXO axes to promote its propagation
    Cang Li, Peng Zhang, Pan-Pan Hong, Guo-Juan Niu, Xiaopei Wang, Xiao‐Fan Zhao, Jin‐Xing Wang · 2023 · International Journal of Biological Macromolecules
22. Deregulation of protein phosphatase 2A inhibitor SET is associated with malignant progression in breast cancer
    Katsunori Tozuka, Pattama Wongsirisin, Shigenori E. Nagai, Yasuhito Kobayashi, Miki Kanno, Kazuyuki Kubo, Ken Takai, Kenichi Inoue, Hiroshi Matsumoto, Yoshihito Shimizu et al. · 2021 · Scientific Reports
23. Preclinical Validation of Tumor-Penetrating and Interfering Peptides against Chronic Lymphocytic Leukemia
    Lorena Simón‐Gracia, Séverine Loisel, Valeria Sidorenko, Pablo Scodeller, Christophe Parizot, Éric Savier, Tanguy Haute, Tambet Teesalu, Angelita Rebollo · 2022 · Molecular Pharmaceutics
24. Cellular protrusions in 3D: Orchestrating early mouse embryogenesis
    Tatiana Omelchenko · 2022 · Seminars in Cell and Developmental Biology
25. 2. Adding perphenazine to increase effectiveness of standard glioblastoma chemoirradiation.
    Richard Eric Kast · 2020
26. Defining the Protein Phosphatase 2A (PP2A) Subcomplexes That Regulate FoxO Transcription Factor Localization
    Adeline M. Luperchio, Daniel J. Salamango · 2025 · Cells
27. The Integrator–PP2A complex integrates promoter-proximal premature termination with chromatin context and genome maintenance
    Aixia Song, Danyi Lu, Fei Chen · 2025 · Trends in Biochemical Sciences
28. Serine/Threonine Protein Phosphatases 1 and 2A in Lung Endothelial Barrier Regulation
    Rahul S. Patil, Anita Kovács‐Kása, Boris A. Gorshkov, David J. Fulton, Yunchao Su, Robert Karoly Batori, Alexander D. Verin · 2023 · Biomedicines
29. PP2A and its adapter protein IER5 induce the DNA-binding ability and target gene expression of E2F1 via dephosphorylation at serine 375
    Hiroto Takeuchi, Mayuko Koga, Kuriko Doi, Hiroshi Sakurai · 2023 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
30. Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases
    Howard K.Y. Yu, Sahil Zaveri, Zeeshan Sattar, Michael Schaible, Brais Perez Gandara, Anwar Uddin, Lucas R. McGarvey, Michael H. J. Ohlmeyer, Patrick M. Geraghty · 2023 · Medicina
31. p53/FBXL20 axis negatively regulates the protein stability of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase
    Lepakshe S. V. Madduri, Nichole D. Brandquist, Chitra Palanivel, Geoffrey A. Talmon, Michael J. Baine, Sumin Zhou, Charles A. Enke, Keith R. Johnson, Michel M. Ouellette, Ying Yan · 2021 · Neoplasia
32. Identification of key pathways and genes in the progression of silicosis based on WGCNA
    Jiaqi Lv, Jingwei Xiao, Qiang Jia, Xiangjing Meng, Zhifeng Yang, Shuangshuang Pu, Ming Li, Tao Yu, Yi Zhang, Haihua Wang et al. · 2022 · Inhalation Toxicology
33. Germline mutations in PPP2R1B in patients with a personal and family history of cancer
    Sahar Mazhar, Caitlin M. O’Connor, Alexis Harold, Amanda C. Dowdican, Peter Ulintz, Erika N. Hanson, Yuping Zhang, Michelle F. Jacobs, Sofia Diana Merajver, Mark W. Jackson et al. · 2025 · JCI Insight
34. VPA mediates bidirectional regulation of cell cycle progression through the PPP2R2A-Chk1 signaling axis in response to HU
    Benyu Su, DAVID J. LIM, Chenyang Qi, Zhongwei Zhang, Junxiao Wang, Fengmei Zhang, Chao Dong, Zhihui Feng · 2023 · Cell Death and Disease
35. A translational study for biomarker identification of PEP-010, a pro-apoptotic peptide restoring apoptosis in cancer models
    Diego Germini, Rayan Farhat, Laura Dadon, A. Lacroix, Fariba Némati, Angelita Rebollo, Didier Decaudin, Joëlle Wiels, Catherine Brenner · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
36. cAMP-regulated phosphoproteins DARPP-32, ARPP16/19, and RCS modulate striatal signal transduction through protein kinases and phosphatases
    Kyle R. Christensen, Angus Clark Nairn · 2020 · Advances in pharmacology
37. The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte
    Eric Allan Hanse, Min Pan, Wenzhu Liu, Ying Yang, Mari B. Ishak Gabra, Thai Q. Tran, Xazmin H. Lowman, Bryan I. Ruiz, Qiong A Wang, Mei Kong · 2021 · EMBO Reports
38. Transcriptomic Dynamics of a non-coding trinucleotide repeat expansion disorder SCA12 in iPSC derived neuronal cells: signatures of interferon induced response
    Deepak Kumar, Parashar Dhapola, Ashaq Hussain, Rintu Kutum, Achal Kumar Srivastava, Mitali Mukerji, Odity Mukherjee, Mohammed Faruq · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
39. Protein Phosphatase 2A Promotes CD8 + T Cell Effector Function through the Augmentation of CD28 Costimulation
    Kaixiang Zhu, Deepak Rohila, Yuanling Zhao, Dmytro W. Shytikov, Lize Wu, Fan Zhao, Shurong Hu, Qin Xu, Xuexiao Jin, Linrong Lu · 2024 · Research
40. Potential neurotoxins: Okadaic acid and analogs
    Antonello Novelli, Antonio Hernández Daranas, David Cabrera-García, Fernando Ascencio Salazar, M. Teresa Fernández‐Sánchez · 2021 · Advances in neurotoxicology
41. Identification of a Novel Protein Phosphatase 2A Activator, PPA24, as a Potential Therapeutic for FOLFOX-Resistant Colorectal Cancer
    Hannah Johnson, Amandeep Singh, Asif Raza, Congzhou Mike Sha, Jian Wang, Krishne Gowda, Zhihang Shen, Nair Hariprasad Haritha, Chenglong Li, Nikolay V. Dokholyan et al. · 2024 · Journal of Medicinal Chemistry
42. Paradoxical action of PP2A inhibition and its potential for therapeutic sensitization
    Yue Jiang, Ying Yuan, Guanglei Qiao, Zhoufeng Deng, Zimei Liu, Yan Zhang, Liping Yu, Hongjian Lin, Lijun Ma, Jianjun Zhang · 2024 · Journal of Cellular Physiology
43. p53abn high-risk endometrial cancer with PPP2R1A mutation might not benefit from adjuvant chemotherapy
    Qingxia Zhang, Yue Wang, Dan He, Jingyun Sun, Xin Li, Dong Li, Ying Dong, Yan Zhang, Suxia Wang · 2025 · American Journal of Clinical Pathology
44. Prognostic Impact of PPP2R5C Gene Expression in Adult Acute Myeloid Leukemia Patients with Normal Cytogenetics
    Maha A El Taweel, Rania M. Gawdat, Rafaat Abdelfattah · 2019 · Indian Journal of Hematology and Blood Transfusion
45. Vitamin E in Chronic Myeloid Leukemia (CML) Prevention
    L. P. Shvachko, Michael P. Zavelevich, Gluzman Df, Г. Д. Телегеев · 2021 · Biochemistry
46. Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain Injury
    Cristóbal de los Rı́os, Lucía Viejo, Victoria Jiménez, Natalia Hernández Juárez, Natália Alves Martins, Jesús Miguel Hernández-Guijo · 2023 · Antioxidants
47. Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor, razor 1-1
    Minghua Nie, Emily Nicole Arner, John Prudden, Lana Schaffer, Steven Robert Head, Michael Nicholas Boddy · 2016 · PLoS Genetics
48. A novel function of twins, B subunit of protein phosphatase 2A, in regulating actin polymerization
    Po-An Yeh, Ching‐Jin Chang · 2017 · PLoS ONE
49. Protein phosphatase 2A as a therapeutic target in pancreatic cancer: past insights, recent advances, and future directions
    Vidhi M. Shah, Rosalie C. Sears · 2025 · Current Opinion in Physiology
50. SERTAD1 is a novel substrate adapter for protein phosphatase 2A and induces site-specific dephosphorylation of heat shock factor 1
    Haruka Sugiyama, Taisei Nakada, Koyo Yano, Hiroshi Sakurai · 2025 · International Journal of Biological Macromolecules
51. Structure–Activity Relationships of Anabaenopeptins as Carboxypeptidase and Phosphatase Inhibitors
    Megan L. Quandt, Judy A. Westrick, Jeremy J. Kodanko · 2026 · ACS Chemical Biology
52. Balancing the Edge: Phosphatases as Homeostatic Buffers of Oncogenic Kinase Signaling in Cancer
    Patrick A. H. Ehm · 2026 · Kinases and Phosphatases
53. SETDB2 interacts with BUBR1 to induce accurate chromosome segregation independently of its histone methyltransferase activity
    Yanhong Tu, Haomiao Zhang, Jialin Xia, Yu Zhao, Ruifang Yang, Jing Chun Feng, Xueyun Ma, Jing Li · 2023 · FEBS Open Bio
54. Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor
    Shasha Shi, Xueni Li, Christopher Alderman, Lars Wick, Wei Huang, North Foulon, Lingdi Zhang, John J. Rossi, Wenxin Hu, Shouqing Cui et al. · 2025 · Journal of Biological Chemistry
55. Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor development
    Jiaen Sun, Minglei Yang, Weidi Zhao, Fajiu Wang, Liangwei Yang, Chuntao Tan, Tianjun Hu, Huangkai Zhu, Guofang Zhao · 2022 · Frontiers in Genetics
56. The role of protein phosphatase 2A tau axis in traumatic brain injury therapy
    Maibouge Tanko Mahamane Salissou, Yacoubou Abdoul Razak Mahaman, Xiaochuan Wang, Rabiu Abdussalam Magaji · 2022 · Beni-Suef University Journal of Basic and Applied Sciences
57. Characterisation of the long noncoding RNA GHSROS in prostate and breast cancer
    Patrick B. Thomas · 2018 · Queensland University of Technology
58. PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers
    Anna Aakula, Aleksi Isomursu, Christian Rupp, Andrew M. Erickson, Otto Kauko, Pragya Shah, Artur Padzik, Yuba Raj Pokharel, Amanpreet Kaur, Song-Ping Li et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
59. Pathogen effector forms a hexameric phosphatase holoenzyme with host core enzyme to promote disease
    Jinlong Wang, Hui Li, Wei Dong Sun, Jiuyu Wang, Xiaodong Fang, Xiaoqi Yang, Chao Liu, Gang Sheng, Wenbo Ma, Yanli Wang · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
60. Dual compartment utility of BRET-based biosensors for PPP2R5A/B56α, a cancer-associated B regulatory subunit of PP2A
    Hirofumi Yamauchi, Atsuro Oishi, Masahiko Ajiro, Atsuhito Nakayama, Kazuki Nishimura, Michiko Kurikawa, Mina Yoshida, Rei Kudo, Minori Koizumi, Takuya Izumi-Tamura et al. · 2025 · BioTechniques
61. Interplay Between Protein Phosphatase 2A (PP2A) and SE Translocation (SET) as Macromolecular Target of Anticancer Compounds: A Combined Computational and Experimental Study
    Giovanni Ribaudo, Mario Angelo Pagano, Margrate Anyanwu, Matteo Giannangeli, Marika Vezzoli, Andrea Visentin, Federica Frezzato, Livio Trentin, Anna Maria Brunati, Alessandra Gianoncelli · 2025 · Macromol—A Journal of Macromolecular Research
62. Phosphatase PP2A promotes RTA dephosphorylation to impair KSHV lytic replication
    Lei Bai, Lianghui Dong, Jiazhen Dong, Xiaowei Liang, Jiangwei Peng, Yuncai Chen, Xiaoyi Sun, Yuting Chen, Xintong Li, Hua Long Cai et al. · 2025 · PLoS Pathogens
63. Small Molecule Activator of Phosphatase PP2A Remodels Scaffold PR65 Structural Dynamics To Promote Holoenzyme Assembly
    Sema Zeynep Yilmaz, Anupam Banerjee, Satyaki Saha, Michael H. J. Ohlmeyer, Reuven Gordon, Laura S. Itzhaki, İvet Bahar, Mert Gür · 2026 · JACS Au
64. Small Molecule Activators of Protein Phosphatase 2A Exert Global Stabilizing Effects on the Scaffold PR65
    Mohsin M. Naqvi, Maria Zacharopoulou, Satyaki Saha, Anupam Banerjee, Sema Zeynep Yilmaz, Vanda Šunderlíková, Christopher M. Johnson, Janet R. Kumita, Shang-Hua Yang, Reuven Gordon et al. · 2026 · JACS Au
65. Protein phosphatase 2A regulates senescence and immunogenicity in medulloblastoma models
    Winson S. Ho, Isha Mondal, Jingjing Liu, Raymond Sun, Jiawei Huo, Chao Gao, Oishika Das, Daren Tieu, Jingqi Sun, Hanchen Lin et al. · 2026 · Journal of Clinical Investigation
66. Protein phosphatase 2A/Hedgehog pathway governs efferocytosis of pulmonary macrophages and participates in nanoplastics-induced mouse lung injury
    Jiaxin Zhang, Y M Zhang, Lixian Wen, Ziyan Li, Yulu Cai, Mengting Wan, Wenhua Li, Zhu Xiaonian, Yaqin Pang, Daochuan Li et al. · 2026 · Cell Biology and Toxicology
67. Beyond cartilage degeneration: osteoarthritis as a systems failure of inflammation regulation
    David Bar‐Or, Williams, Melissa A Hausburg, Gregory W. Thomas, Raphael Bar-Or · 2026 · Frontiers in Medicine
68. Abnormal cortical excitability in patients with spinocerebellar ataxia type 12
    Amitabh Bhattacharya, Albert Stezin, Nitish L. Kamble, Sujas Bhardwaj, Ravi Yadav, Pramod Kumar Pal · 2024 · Parkinsonism & Related Disorders
69. A small molecule inhibitor of leucine carboxyl methyltransferase-1 inhibits cancer cell survival
    Oneida A. Arosarena, A. Sami Sarıbaş, E. P. Papadopoulos · 2024 · Frontiers in Drug Discovery
70. PP2A forestalls mitophagy by dephosphorylating Parkin and ubiquitin
    Shang-Xiang Ye, Xingyu Liu, Ze-Feng Nie, Ling-Shen Meng, Xu Dong, Fangfang Li, Zhou Gong, Wei Yang, Weiping Zhang, Chun Tang · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
71. Influence of Point Mutations on PR65 Conformational Adaptability: Insights from Nanoaperture Optical Tweezer Experiments and Molecular Simulations
    İvet Bahar, Anupam Banerjee, Samuel Mathew, Mohsin M. Naqvi, Sema Zeynep Yilmaz, Maria Zachoropoulou, Pemra Doruker, Janet R. Kumita, Shang-Hua Yang, Mert Gür et al. · 2023 · Research Square
72. Serine/Threonine-Protein Phosphatase 2A
    Veerle Janssens · 2016 · Springer eBooks
73. The FEBS Journal in 2018 – putting a bit of color in your life, and your figures
    Séamus J. Martin · 2018 · FEBS Journal
74. A Guide to ‘A Guide to….’ articles, some thoughts on impact, and why you really should publish with The FEBS Journal
    Séamus J. Martin · 2018 · FEBS Journal
75. Calcium-binding proteins that are type B″ regulatory subunits of phosphatase 2A in Giardia intestinalis
    Magda E. Alvarado, Claudia Consuelo Rubiano, William Sánchez, Andrea Díaz, Moisés M. Wasserman · 2018 · Parasitology Research
76. Response by El Refaey et al to Letter Regarding Article, “Protein Phosphatase 2A Regulates Cardiac Na + Channels”
    Mona El Refaey, Hassan Musa, Sakima Ahmad Smith, Philip F. Binkley, Elisa A. Bradley, Thomas J. Hund, Peter J. Mohler · 2019 · Circulation Research
77. Role of Protein Phosphatase-2A in Regulating Monocyte Activation by Soluble and Crystalline Uric Acid in Gout
    Sandy Elsayed · 2020
78. Refining the Class IIa HDAC/MEF2 Paradigm in Muscle Biology: More than Meets the Eye
    F. Dequiedt, Thomas Cherrier · 2020 · Journal of Cellular Signaling
79. KiRNet: Integrated, Kinase-Centered Network Modeling Predicts Mechanisms Behind Phenotypic Associations
    Thomas Bello, Marina Chan, Martin G. Golkowski, Nithisha Khasnavis, Michele Ceribelli, Shao‐En Ong, Craig J. Thomas, Taranjit S. Gujral · 2020 · SSRN Electronic Journal
80. HBV Infection Promotes the Occurrence and Development of Hepatocellular Carcinoma through Impairing the Inhibitory Effect of PPP2R5A on MAPK/AKT/WNT Signaling Pathway
    Xuejing Lin, Ziming Mao, Qin Zhang, Lei Chen, Haihua Qian, Chunying Liu, Changqing Su · 2021 · Engineering
81. The Key Role of the Phosphatase PP2A in the Development of Acute Myeloid Leukemia
    Javier Marco, Irene Peris, Carmen Vicente, Elena Arriazu · 2021 · IntechOpen eBooks
82. Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells
    Sunday Okutachi, Ganesh babu Manoharan, Daniel Abankwa · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
83. PP2Acα regulates epidermal cell proliferation via the EGFR/AKT/mTOR pathway in psoriasis‐like skin lesions caused by PPP2CA deficiency
    Ting Tao, Yiwen Chen, Jianquan Chen, Chao Lian, Shengjing Xu, Min Zhang, Chao Fang · 2022 · Experimental Dermatology
84. High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation
    Jiajia He, Lei Shang, Qun-Wei Yu, Ning Jiao, Shuang Qiu, Wei-Xiong Zhu, Dongfeng Wu, Yun-Er Tian, Qing Zhang · 2021 · World Journal of Gastrointestinal Oncology
85. Serine/Threonine-Protein Phosphatase 2A
    Veerle Janssens · 2017 · Springer eBooks
86. Caracterização da interação da proteína TIPRL com fosfatases tipo 2A em cultura de células
    Ana Amélia Sanchez Iacia · 2021
87. Functional regulation of the protein phosphatase PPM1M by phosphorylation at multiple sites with Ser/Thr-Pro motifs
    Jin Osawa, Masataka Karakawa, Aoi Taniguchi, Yuiko Inui, Chika Usuki, Atsuhiko Ishida, Isamu Kameshita, Noriyuki Sueyoshi · 2024 · Archives of Biochemistry and Biophysics
88. Computational investigations into structure and function impact of novel mutations identified in targeted exons from ovarian cancer cell lines
    Rucha M. Wadapurkar, Aruna Sivaram, Renu Vyas · 2024 · Journal of Biomolecular Structure and Dynamics
89. Pharmacogenomics: Personalized medicine and its impact on breast cancer
    Omar Obaid Alharbi · 2019 · International Journal of Health Sciences
90. Protein phosphatase 2A activators under investigation for smoking-related chronic obstructive pulmonary disease and related disorders
    Sabina A Antoniu, Setfan Rascu · 2024 · Expert Opinion on Investigational Drugs
91. Antitumoral Effect on Liver Cancer of a Tumor-Penetrating and Interfering Peptide
    Éric Savier, Pierre Tufféry, Heriberto Bruzoni-Giovannelli, Rachid Boudjelloul, Angelita Rebollo · 2025 · Methods in pharmacology and toxicology
92. Aging-dependent dysregulation of EXOSC2 is maintained in cancer as a dependency
    Maria Skamagki, Cheng Zhang, Ezgi Hacisuleyman, Giuseppe Galleti, Chao Wu, Vinagolu K. Rajasekhar, HyoKyeong Cha, Deniz Ata, Jongjin Kim, Taylor Weisskittel et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
93. A study conducted in breast cancer cells found that (valproic acid) inhibits CIP2A/c-MYC/PI3K/Akt/mTOR signaling molecules and PD-L1
    Elahe Zeinali, Vahid Bagheri, Esmaeil Rostami, Atena Mansouri, Gholamreza Anani Sarab · 2025 · Human Gene
94. PP2A activation drives aberrant macropinocytosis and cell death in pancreatic ductal adenocarcinoma
    Garima Baral, Claire M. Pfeffer, Sara N. Filippelli, Indiraa Doraivel, Brittany N. Heil, Lauren E. Gartenhaus, Kasi Hansen, Joy Wu, Goutham Narla, Emma H. Doud et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
95. Additional file 1 of Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways
    Stefania Livia Ciummo, Carlo Sorrentino, Cristiano Fieni, Emma Di Carlo · 2023 · Figshare
96. Additional file 1 of Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis
    Guy Nadel, Yao, Zhong, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Ziv, Tamar, Zvi Naor, Arie Admon, Rony Seger · 2024 · Figshare
97. Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality Control
    Regina Baur, Laura A. Hehl, Gajanan J. Sathe, Thomas Lunardi, Jonathan Schneider, Anna-Sophia Krebs, Juan Carlos Silva, Diane L. Haakonsen, Sebastian M. Waszak, Joachim Lingner et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
98. New Approaches to the Treatment of Chronic Myeloid Leukemia
    L. P. Shvachko, Svitlana Antonenko, Michael Zavelevich, Irene Gartovska, М. В. Дыбков, Dmytro Gur`yanov, Г. Д. Телегеев · 2026 · IntechOpen eBooks
99. Effects of Mutations on Tandem-Repeat Proteins Conformation Mechanisms. Application to the Phosphatase PP2A
    Matias Chiappinelli, Tadeo Enrique Saldaño, Silvio C. E. Tosatto, Sergei Grudinin, Gustavo D. Parisi, Sebastian Fernández-Alberti · 2026 · Journal of Chemical Information and Modeling
100. Identification and characterization of new Greatwall kinase substrates
     Lena Sundermann · 2018