Initiation and perpetuation of NLRP 3 inflammasome activation and assembly

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2. High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
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4. Allopurinol abates hepatocellular carcinoma in rats via modulation of NLRP3 inflammasome and NF-κB pathway
   Heba A. Bahriz, Rania Ramadan Abdelaziz, Dalia H. El‐Kashef · 2024 · Naunyn-Schmiedeberg s Archives of Pharmacology
5. Stealth in non-tuberculous mycobacteria: clever challengers to the immune system
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7. Interaction of 22 Risk SNPs with Helicobacter Pylori Infection and Risk of Gastric Cardia Adenocarcinoma
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8. Endogenous DAMPs, Category I: Constitutively Expressed, Native Molecules (Cat. I DAMPs)
   W. Land · 2018 · Damage-Associated Molecular Patterns in Human Diseases
9. Cellular Inflammatory Responses
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10. Pervasive loss of regulated necrotic cell death genes in elephants, hyraxes, and sea cows ( Paenungualta )
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12. Potential value of expression of receptor accessory protein 4 for evaluating the prognosis of lower-grade glioma patients
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15. Extinguishing the flames of inflammation: retardant effect of chlorquinaldol on NLRP3-driven diseases
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16. Inherited Blood Disorders: Advances in Diagnosis and Treatment of Sickle Cell Disease
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17. MAFF mitigates oxidative stress and pyroptosis in cardiopulmonary bypass-induced myocardium injury
    Lei Yuan, Duo Wang, Yale Su, Long Ping Yuan, Mixia Li, Dongdong Zheng, Cuilin Zhu, Hulin Piao, Yong Wang, Zhicheng Zhu et al. · 2025 · Frontiers in Physiology
18. Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins
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19. LncRNAs in inflammasome regulation: Orchestrating cancer signaling and chemoresistance
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20. Inhibiting the NLRP3 inflammasome pathway: An effective way to treat chronic inflammation in experimental autoimmune uveitis
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22. Clusterin protects against HFpEF by inhibiting UCHL1-mediated NLRP3 deubiquitylation and inflammasome activation
    Jiangling Yu, Xiaoxu Kang, Rui Chang, Cheng Zhang, Yang Sl, Lang Chen, Xinbo Wang, Bing Hu, Zixuan Wang, Lili Gong et al. · 2026 · Frontiers in Pharmacology
23. The NLRP3 inhibitor, MCC950, attenuates environmental pollutant PM2.5-induced acute lung injury by inhibiting alveolar macrophage pyroptosis
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24. Isoquercitrin inhibits Streptococcus pneumoniae-induced pyroptosis of BEAS-2B cells by SIRT1-mediated acetylation
    Li Liu, Xian Chen, Xia Li, Zhendong Zhao, Boan Xiao · 2026 · Microbial Pathogenesis
25. Mice humanized by syntenic replacement with full-length NLRP3 disease-associated variants model the clinical cryopyrinopathy continuum
    J. Snouwaert, Mytrang Nguyen, C. A. Gabel, Ivona Aksentijevich, Jenny P.-Y. Ting, Beverly H. Koller · 2026 · JCI Insight
26. Modern Research on Traditional Chinese Ethnomedicines for Rheumatoid Arthritis: Acting Through Signaling Pathways
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27. Quercetin mitigates CUMS-induced depression-like behaviors in rats by regulating argininosuccinic acid-induced astrocyte pyroptosis in the hippocampus
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28. The NLRP3 inflammasome in tuberculosis and its regulatory mechanisms
    Luyan Xiong, Qiao Zhang, Abulimiti Abudukadier, Jianping Xie · 2026 · Cellular Signalling
29. The role of selective autophagy in pathogen infection
    Li Tang, Yinjuan Song, Jian Xu, Yuefeng Chu · 2022 · Chinese Science Bulletin (Chinese Version)
30. Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice
    Daniel H. O’Donovan, David Baker, Giovanni Ciotta, Sébastien L. Degorce, Sylvain Demanze, Millicent Dockerill, Leire Escudero‐Ibarz, Lucy Ireland, Yumeng Mao, Martin J. Packer et al. · 2023 · Bioorganic & Medicinal Chemistry Letters
31. Chromofungin mitigates free fatty acids‐induced endothelial inflammation via inhibition of NOD‐like receptor thermal protein domain‐associated protein 3 mediated by adenosine 5ʹ‐monophosphate‐activated protein kinase
    Qing Lan, Jian Chen, Yongqiang Yang · 2024 · Biotechnology and Applied Biochemistry
32. Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro
    Luis Edgardo Gonzales-Huerta, Thomas J Williams, Renad Aljohani, Brian D. Robertson, Carlton A. Evans, Darius P. H. Armstrong-James · 2026 · PLoS ONE
33. DHA Alleviates Excessive Copper-Induced Hepatocyte Injury by Inhibiting Pyroptosis via the ROS/NLRP3/NF-κB Pathway
    Yufei Cao, Boran Zhou, Weiyin Zhang, Nan Mu, Pingping Zheng, Changhe Geng, Yu Wang · 2025 · Biological Trace Element Research
34. Calcium signaling and inflammasome
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35. The Growing Clinical Relevance of Cellular Stress Responses and Regulated Cell Death
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36. Biologics in severe asthma – a molecular perspective
    Laura Haidar, Carmen Bunu Panaitescu · 2022 · Alergologia
37. NLRP3 inflammasome activation and its inhibitory drugs in connection with COVID-19 infection
    Khashayar Zafar-Mohammadi, Javad Poursamimi, Mahdi Atabaki · 2022 · European Journal of Inflammation
38. NLRP6 in Gram-positive Pneumonia and Sepsis
    Laxman Ghimire · 2019 · Louisiana State University
39. Alleviating Asthma-Induced Mitochondrial Dysfunction and Oxidative Stress: Lactobacillus rhamnosus Intervention via Notch1 Signaling Pathway
    Si Liu, Shaotian Chen, Xin-Yan Jiang, Shang Xiao-yun, Nan Yang · 2024 · Research Square
40. Effects of microbial mitochondriotoxins from food and indoor air on mammalian cells
    Stiina Rasimus · 2016 · Työväentutkimus Vuosikirja
41. Role of the inflammasome pathway in atherosclerosis
    Kristiina Rajamäki · 2015 · Työväentutkimus Vuosikirja
42. NAIP and CARD-only proteins in inflammasome signaling
    Magdalena Matusiak · 2015 · Ghent University Academic Bibliography (Ghent University)
43. NLRP3 and Its Role in Autoinflammatory Disorders
    Sema Ören, Oguz Ozafsar, Erkan Demirkaya · 2016 · Annals of Paediatric Rheumatology
44. Inhibitory Effects of Ethanol on the NLRP3 Inflammasome
    Laura R. Hoyt · 2015 · ScholarWorks -A service of University of Vermont Libraries (University of Vermont)
45. Flavonoids as Cytokine Immunomodulators to Reduce Airway Inflammation via Inhibition of the NF‐κB Signalling Pathway: A Systematic Overview
    Rajiv Gandhi Gopalsamy, Dhanabalan Karthik, Alan Bruno Silva Vasconcelos, Gabriel Campos de Sousa Leão, Maria LD Almeida, Gurunagarajan Sridharan, Gnanasekaran Jothi, Thiruchenduran Mohana, Narendra Narain, Ricardo Q Gurgel · 2020 · Wiley eBooks
46. Molecular Mechanisms Leading to Interleukin-1β Release by Macrophages in Response to Wear and Corrosion Products from Metal Implants
    Jennifer Archibald · 2020 · uO Research (University of Ottawa)
47. Innate immune signaling and sex differences contribute to neurocognitive impairment, neuroinflammation, and mitochondrial rewiring in a mouse model of Gulf War illness
    Joshua D. Bryant, Maheedhar Kodali, Bing Shuai, Saeed S. Menissy, Paige J. Graves, Ashok Kumar Shetty, Laura Ciaccia West, Andrew Phillip West · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
48. NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model
    Elísabet Alcocer‐Gómez, Beatriz Castejón‐Vega, Jéssica Núñez‐Vasco, Débora Lendines‐Cordero, José Manuel Navarro-Pando, Mario David Cordero · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
49. Role of NLRP3 Inflammasomes in Obesity-Induced Cardiovascular Diseases
    Krishna Murthy Boini, Pin‐Lan Li, Saisudha Koka · 2020 · Springer eBooks
50. Case Study: Health Risks from Asbestos Exposures
    Louis Anthony Cox · 2020 · International series in management science/operations research/International series in operations research & management science
51. Melatonin Attenuates Pyroptosis Upon Spinal Nerve Ligation in Rats via the NF-κB/NLRP3 Inflammasome Signaling Pathway
    Yihao Wang, Xiao Wei Gao, Yuru Tang, Nannan Zhang, Zhaojun Liang, Juan Liu, Yan Li · 2021 · Research Square
52. Avaliação das populações de macrófagos de fenótipo M1/M2 e marcadores de ativação do inflamassoma em pacientes com poliarterite nodosa cutânea
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53. Expression of NLRP3 inflammasome proteins in ExpiCHO‐S mammalian cells reveals oligomerization properties that are highly sensitive to solution conditions
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54. Mitochondria-targeted drugs and immune function
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55. Molecular aspects of neuroinflammation: Contribution of eicosanoids, cytokines, and chemokines
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56. TGF-β activates NLRP3 Inflammasome by an Autocrine Production of TGF-β in LX-2 Human Hepatic Stellate Cells
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57. Multifaceted Functions of NOD-Like Receptor Proteins in Myeloid Cells at the Intersection of Innate and Adaptive Immunity
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58. Research Perspectives of NLRP3 in the Pathogenesis of Cardiovascular Diseases
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59. Bilirubin Inhibits NLRP3 Inflammasome Activation by Maintaining the Stability of Mitochondria Membranes
    Yufei Li, Hongda Sheng, Jing Qian, Yì Wáng · 2021 · SSRN Electronic Journal
60. Potential Value of Expression of Receptor Accessory Protein 4 in Lower - Grade Glioma For Antitumor Immunotherapy
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61. Aspergillus lentulus Activates the NLRP3 Inflammasome
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62. [WP1130 relieves septic shock in mice by inhibiting NLRP3 inflammasome activation].
    Lili Lu, Didi Liu, Y Yang, F Wang · 2022 · PubMed Central
63. Timosaponin BⅡ alleviates DSS-induced ulcerative colitis in mice by inhibiting NLRP3
    Meng Feng, C Y Liu · 2023
64. Timosaponin BⅡ alleviates DSS-induced ulcerative colitis in mice by inhibiting NLRP3
    Changhui Liu · 2023
65. Causal relationships between new 412 gut microbiota, 731 inflammatory cells,91 inflammatory proteins and circulating leukocytes and subarachnoid hemorrhage: a Multi-omics, Bidirectional Mendelian randomization study and Meta-analysis
    Congzhi Yan, Yun Li · 2023 · Research Square
66. Fluvoxamine maleate ameliorates Alzheimer disease pathology by mitigating amyloid-beta load and neuroinflammation in 5XFAD mice
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67. Prospects of Hydrogen Medicine Based on Its Protective Effects on Mitochondrial Function
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68. Inflammasomes, Inflammation and Neuropathic Pain
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69. Additional file 7 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Wang, Bo, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei‐Qiang Gao, Huiming Xu, Meijin Guo · 2022 · Figshare
70. Additional file 4 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Wang, Bo, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei‐Qiang Gao, Huiming Xu, Meijin Guo · 2022 · Figshare
71. Additional file 6 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Wang, Bo, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei‐Qiang Gao, Huiming Xu, Meijin Guo · 2022 · Figshare
72. Additional file 5 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Wang, Bo, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei‐Qiang Gao, Huiming Xu, Meijin Guo · 2022 · Figshare
73. Additional file 8 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Wang, Bo, Ali Mohsin, Zhimin Cheng, Weijie Hao, Wei‐Qiang Gao, Huiming Xu, Meijin Guo · 2022 · Figshare
74. Role of pattern recognition receptors in cardiac remodeling
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75. MAVS Safeguards Mitochondrial Integrity to Drive a Potent Intrinsic Antiviral Program
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76. CUEDC2 improves pyroptosis and kidney damage in diabetic kidney disease by inhibiting NLRP3 inflammasome activation
    Pei‐Yuan Yang, Liming Fan, Daijiao Yuan, Jiarun Xie, Yanyu Luo, Qin Zeng, Wenming Lin, Zhifang Li, Zijie Huang, Weiqiang Jiang et al. · 2025 · Cellular Signalling
77. Pyroptosis in Alopecia Areata: Synthesizing Emerging Hypotheses and Charting a Path to New Therapies
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78. Additional file 1 of Sodium tanshinone IIA sulfonate ameliorates neointima by protecting endothelial progenitor cells in diabetic mice
    Heng, Yan-Yan, Shang, Hui-Juan, Zhang, Xia-ze, Wei, Wei · 2023 · Figshare
79. Additional file 1 of Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
    Jia Zhao, Liu, Hongbin, Hong, Zhixian, Luo, Wei, Mu, Wenqing, Xiaorong Hou, Guang Xu, 方志娥, Lutong Ren, Liu, Tingting et al. · 2023 · Figshare
80. Additional file 1 of Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity
    Bo Wang, Zhang, Ge, Hu, Yuwen, Mohsin, Ali, Chen, Zhimin, Weijie Hao, Zhanxia Li, Weiqiang Gao, Guo, Meijin, Xu, Huiming · 2024 · Figshare
81. Additional file of Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity
    Gao, Yuan, Xu, Guang, Ma, Li, Shi, Wei, Wang, Zhilei, Zhan, Xiaoyan, Qin, Nan, He, Tingting, Guo, Yuming, Niu, Ming et al. · 2021 · Figshare
82. Additional file 1 of Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats
    Zhang, Zhiheng, Bai, Hui, Xiangying Ma, Shen, Meilun, Rouqian Li, Qiu, Di, Li, Siyao, Gao, Li · 2021 · Figshare
83. Additional file 1 of Britannilactone 1-O-acetate induced ubiquitination of NLRP3 inflammasome through TRIM31 as a protective mechanism against reflux esophagitis-induced esophageal injury
    Ju Liu, Yang Xiao, Qianfei Xu, Xu, Yunyan, Guo, Manman, Hu, Yun, Wang, Yan, Wang, Yi · 2024 · Figshare
84. Additional file 2 of Sodium tanshinone IIA sulfonate ameliorates neointima by protecting endothelial progenitor cells in diabetic mice
    Heng, Yan-Yan, Shang, Hui-Juan, Zhang, Xia-ze, Wei, Wei · 2023 · Figshare
85. Additional file 2 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Wang, Yuli, Jianhua Lin, Bo Wang, Mohsin, Ali, Cheng, Zhimin, Weijie Hao, Weiqiang Gao, Xu, Huiming, Meijin Guo · 2022 · Figshare
86. Additional file 1 of Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
    Banerjee, Sharmistha, Taeyeop Park, Kim, Yoo Sun, Kim, Hee-Yong · 2023 · Figshare
87. Additional file 4 of Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity
    Bo Wang, Zhang, Ge, Hu, Yuwen, Mohsin, Ali, Chen, Zhimin, Weijie Hao, Zhanxia Li, Weiqiang Gao, Guo, Meijin, Xu, Huiming · 2024 · Figshare
88. Additional file 3 of Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity
    Bo Wang, Zhang, Ge, Hu, Yuwen, Mohsin, Ali, Chen, Zhimin, Weijie Hao, Zhanxia Li, Weiqiang Gao, Guo, Meijin, Xu, Huiming · 2024 · Figshare
89. Additional file 3 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Yuli Wang, Jianhua Lin, Bo Wang, Mohsin, Ali, Cheng, Zhimin, Weijie Hao, Weiqiang Gao, Xu, Huiming, Meijin Guo · 2022 · Figshare
90. Additional file 2 of The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy
    Yu, Qiao, Shi, Huiying, Ding, Zhen, Wang, Zhe, Hailing Yao, Lin, Rong · 2023 · Figshare
91. Additional file 1 of Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro
    Zhang, Ge, Wang, Yuli, Jianhua Lin, Bo Wang, Mohsin, Ali, Cheng, Zhimin, Weijie Hao, Weiqiang Gao, Xu, Huiming, Meijin Guo · 2022 · Figshare
92. Additional file 2 of Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
    Jia Zhao, Liu, Hongbin, Hong, Zhixian, Luo, Wei, Mu, Wenqing, Xiaorong Hou, Guang Xu, 方志娥, Lutong Ren, Liu, Tingting et al. · 2023 · Figshare
93. Additional file 4 of Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
    Jia Zhao, Liu, Hongbin, Hong, Zhixian, Luo, Wei, Mu, Wenqing, Xiaorong Hou, Guang Xu, 方志娥, Lutong Ren, Liu, Tingting et al. · 2023 · Figshare
94. Additional file 2 of Uncovering impaired mitochondrial and lysosomal function in adipose-derived stem cells from obese individuals with altered biological activity
    Bo Wang, Zhang, Ge, Hu, Yuwen, Mohsin, Ali, Chen, Zhimin, Weijie Hao, Zhanxia Li, Weiqiang Gao, Guo, Meijin, Xu, Huiming · 2024 · Figshare
95. Additional file 1 of Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome
    Hefei Huang, He, Xuemei, 世玲 朱, Yu, Jingtao, Lu, Zibin, Huihui Cao, 欧金英, Chen, Xi, Yan, Lijun, Yang, Jiabin et al. · 2024 · Figshare
96. Additional file 1 of Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice
    Shuai Shao, Xu Chengbo, Chen, Cheng-Juan, Gaona Shi, Guo, Qing-Lan, Zhou, Yu, Yazi Wei, Wu, Lei, Jiangong Shi, Zhang, Tian-Tai · 2021 · Figshare
97. Additional file 3 of Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
    Jia Zhao, Liu, Hongbin, Hong, Zhixian, Wei Luo, Mu, Wenqing, Xiaorong Hou, Guang Xu, 方志娥, Lutong Ren, Liu, Tingting et al. · 2023 · Figshare
98. Additional file 2 of Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity
    Gao, Yuan, Xu, Guang, Ma, Li, Shi, Wei, Wang, Zhilei, Zhan, Xiaoyan, Qin, Nan, He, Tingting, Guo, Yuming, Niu, Ming et al. · 2021 · Figshare
99. Ginsenoside Rg1 ameliorates depression-like behaviors in mice by inhibiting astrocyte pyroptosis via Cx43-dependent restoration of mitophagy flux
    Zan Yang Xing, Xin-Mu Li, Yuan-Chun Wang, Peng-Yu Chen, Xueying Yang, Huiqin Wang, Meng Zhang, Ai-Ping Chen, Shi-Feng Chu, Zhen‐Zhen Wang et al. · 2026 · International Immunopharmacology
100. YTHDC2-mediated RAB20 degradation regulates NLRP3 inflammasome priming to improve chronic glomerulonephritis
     Yong Yan Tang, Ya Chen Gao, Tao Liu, Jian Wu, Liang Bing Wei, Jia Rong Gao · 2026 · Gene